ABSTRACT
Neurofibromatosis 1 is the commonest neurocutaneous autosomal dominant disorder with full penetrance, although expression may not be complete by the age of five years. Lisch nodules, however, are predominantly visible in children usually after the age of six years. Therefore, it is important to appreciate that their absence before this age does not pre-empt the diagnosis. A child being treated for hypertension of unknown aetiology with cafe au lait lesions presented to the ophthalmologist with blurred vision. Clinical examination revealed Lisch nodules which confirmed the suspicion of neurofibromatosis 1 as per National Institutes of Health criteria. The aim of this report is to highlight the importance of regular ophthalmic screening, both in suspected and confirmed cases, as these patients have long-term sequelae.
ABSTRACT
A new benzylisoquinoline alkaloid, argemexirine, together with two known protoberberine alkaloids, dl-tetrahydrocoptisine and dihydrocoptisine, have been isolated from the methanolic extract of the whole plant of Argemone mexicana L. The compounds were identified by spectral and chemical evidence. This is the first report of these alkaloids in this plant species.
Subject(s)
Alkaloids/chemistry , Argemone/chemistry , Isoquinolines/chemistry , Alkaloids/isolation & purification , Berberine/analogs & derivatives , Berberine/chemistry , Isoquinolines/isolation & purification , Magnetic Resonance Spectroscopy , Methanol , Methylation , Plant Extracts/analysis , Solvents , Spectrophotometry, Infrared , Spectrophotometry, UltravioletABSTRACT
The case of a two-year-old boy with hypertensive encephalopathy secondary to Hepatitis B-associated polyarteritis nodosa is presented. Polyarteritis nodosa is a rare condition in children and its association with Hepatitis B viral infection is also rare.
Subject(s)
Hepatitis B/complications , Hypertensive Encephalopathy/etiology , Polyarteritis Nodosa/complications , Polyarteritis Nodosa/diagnosis , Antibodies, Antineutrophil Cytoplasmic/blood , Child, Preschool , Hepatitis B/diagnosis , Humans , Hypertensive Encephalopathy/diagnosis , Kidney/pathology , MaleABSTRACT
The case of a two-year old boy with hypertensive encephalopathy to Hepatitis B-associated polyarteritis nodosa is presented. Polyarteritis nodosa is a rare condition in children and its association with Hepatitis B viral infection is also rare (AU)
Subject(s)
Child, Preschool , Case Reports , Humans , Male , Hepatitis B/complications , Polyarteritis Nodosa/complications , Polyarteritis Nodosa/diagnosis , Antibodies, Antineutrophil Cytoplasmic/blood , Hepatitis B/diagnosis , Kidney/pathologyABSTRACT
The case of a two-year old boy with hypertensive encephalopathy to Hepatitis B-associated polyarteritis nodosa is presented. Polyarteritis nodosa is a rare condition in children and its association with Hepatitis B viral infection is also rare
Subject(s)
Child, Preschool , Humans , Male , Polyarteritis Nodosa/complications , Polyarteritis Nodosa/diagnosis , Hepatitis B/complications , Antibodies, Antineutrophil Cytoplasmic/blood , Hepatitis B/diagnosis , Kidney/pathologyABSTRACT
This study was aimed to evaluate the immuno-modulator role of homeopathic remedies in Human Immunodeficiency Virus (HIV) infection. A randomised double blind clinical trial was conducted to compare the effect of homeopathic remedies with placebo, on CD4+ve T-lymphocytes in HIV infected individuals, conforming to Centres for Disease Control (CDC) stage II & III. 100 HIV+ve individual beteen 18-50y (71 percent males) were included in the study. 50 cases conformed... (AU)
Subject(s)
Comparative Study , Humans , Male , Female , Adolescent , Adult , Middle Aged , Acquired Immunodeficiency Syndrome/therapy , CD4-Positive T-Lymphocytes , IndiaABSTRACT
A 6 month study comprising of a Double-blind Placebo-controlled trial of homoeopathic medicines in HIV/AIDS under 3 separate schemes (I) Asymptomatic HIV infection and (II) Persistent generalised lymphadenopathy (50 subjects each) was undertaken from June 1995 to February 1997. As soon as a subject had undergone 6 months of study, they were put on an indicated medicine. Unblinding... (AU)
Subject(s)
Acquired Immunodeficiency Syndrome , Homeopathic Therapeutics , IndiaABSTRACT
To assess the role of homoeopathic medicines in the treatment of the asymptomatic phase of HIV infection, a pilot research study was undertaken by the Central Council for Research in Homoeopathy (India) starting in May 1989. 129 symptomatic HIV carriers (120 male and 9 female) were treated with homoeopathic medicines on the basis of the individuals' constitutional (both mental/emotional and physical) characteristics. The medicines were prescribed in potencies varying from 30CH to 10M and in varying dosage, depending on the age and constitution of the individual patients. 12 of the patients studied have reverted back to negative serology for HIV antibodies after treatment varying from 3 to 16 months (mean duration of treatment between entry and reversal of seroconversion for HIV antibodies 7.25 months). All patients who continue to remain symptom free are receiving follow-up treatment. Efforts are being made to evaluate their haematological and immunological status in detail