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1.
J Surg Res ; 263: 151-154, 2021 07.
Article in English | MEDLINE | ID: mdl-33652177

ABSTRACT

BACKGROUND: Postoperative oral antibiotic management at discharge for perforated appendicitis varies by institution. A prior study at our institution led to a decrease in antibiotic therapy in patients without leukocytosis. A subsequent protocol change eliminated the white blood cell count check and oral antibiotics if discharge criteria were met by postoperative day seven. We hypothesized this change could be made without an increase in abscess or readmission rates. METHODS: We conducted a retrospective review of patients with perforated appendicitis over two 1-year periods after institutional review board approval (262061). In the pre-protocol group, a white blood cell count was checked at discharge and patients with leukocytosis were prescribed oral antibiotics to complete a total of 7 d. In the post-protocol group, no white blood cell count was checked and patients were discharged home without antibiotics. RESULTS: There were a total of 174 patients with complicated appendicitis in the two 1-year periods with 129 (74%) patients with perforated appendicitis discharged before postoperative day seven. The pre-protocol group included 71 children, and post-protocol included 58 children. There were no differences between mean postoperative days to discharge (2.57 versus 3, P = 0.0896), postoperative abscess rate (12.7% versus 12.1%, P = 1.0000), or readmission rate (12.7% versus 17.2%, P = 0.6184). None of the patients in the post-protocol group were discharged home with oral antibiotics compared with 22.5% in the pre-protocol group (P < 0.001). CONCLUSIONS: For pediatric patients with perforated appendicitis discharged before postoperative day seven, stopping antibiotics at the time of discharge significantly decreased our home antibiotic use without an increase in postoperative morbidity.


Subject(s)
Abdominal Abscess/epidemiology , Antibiotic Prophylaxis/standards , Appendicitis/surgery , Intestinal Perforation/surgery , Postoperative Care/standards , Postoperative Complications/epidemiology , Abdominal Abscess/etiology , Abdominal Abscess/prevention & control , Administration, Oral , Anti-Bacterial Agents/administration & dosage , Antibiotic Prophylaxis/statistics & numerical data , Appendectomy/adverse effects , Appendicitis/complications , Child , Humans , Intestinal Perforation/etiology , Male , Patient Discharge/standards , Patient Discharge/statistics & numerical data , Patient Readmission/statistics & numerical data , Postoperative Care/methods , Postoperative Care/statistics & numerical data , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Practice Guidelines as Topic , Retrospective Studies , Self Administration/standards , Self Administration/statistics & numerical data
2.
J Pediatr Surg ; 55(8): 1535-1541, 2020 Aug.
Article in English | MEDLINE | ID: mdl-31954555

ABSTRACT

PURPOSE: No consensus guidelines exist for timing of enterostomy closure in neonatal isolated intestinal perforation (IIP). This study evaluated neonates with IIP closed during the initial admission (A1) versus a separate admission (A2) comparing total length of stay and total hospital cost. METHODS: Using 2012 to 2017 Pediatric Health information System (PHIS) data, 359 neonates with IIP were identified who underwent enterostomy creation and enterostomy closure. Two hundred sixty-five neonates (A1) underwent enterostomy creation and enterostomy closure during the same admission. Ninety-four neonates (A2) underwent enterostomy creation at initial admission and enterostomy closure during subsequent admission. For the A2 neonates, total hospital length of stay was calculated as the sum of hospital days for both admissions. A1 neonates were matched to A2 neonates in a 1:1 ratio using propensity score matching. Multivariate models were used to compare the two matched pair groups for length of stay and cost comparisons. RESULTS: Prior to matching, the basic demographics of our study population included a median birthweight of 960 g, mean gestational age of 29.5 weeks, and average age at admission of 4 days. Eighty-seven pairs of neonates with IIP were identified during the matching process. Neonates in A2 had 91% shorter total hospital length of stay compared to A1 neonates (HR: 1.91; 95% CI for HR: 1.44-2.53; p < .0001). The median length of stay for A1 was 95 days (95% CI: 78-102 days) versus A2 length of stay of 67 days (95% CI: 56-76 days). Adjusting for the same covariates, A2 neonates had a 22% reduction in the average total cost compared A1 neonates (RR: 0.78; 95% CI for RR: 0.64-0.95; p-value = 0.014). The average total costs were $245,742.28 for A2 neonates vs. $315,052.21 for A1 neonates (p < 0.001). CONCLUSION: Neonates with IIP have a 28 day shorter hospital length of stay, $75,000 or 24% lower total hospital costs, and a 22 day shorter post-operative course following enterostomy closure when enterostomy creation and closure is performed on separate admissions. TYPE OF STUDY: Prognosis Study. LEVEL OF EVIDENCE: Level II.


Subject(s)
Enterostomy , Intestinal Perforation/epidemiology , Intestinal Perforation/surgery , Enterostomy/methods , Enterostomy/statistics & numerical data , Gestational Age , Humans , Infant, Newborn , Length of Stay/statistics & numerical data , Time Factors
3.
J Pharm Sci ; 109(3): 1270-1280, 2020 03.
Article in English | MEDLINE | ID: mdl-31758950

ABSTRACT

Mechanical shock may cause cavitation in vials containing liquid formulations of therapeutic proteins and generate protein aggregates and other particulates. To test whether common formulation components such as protein molecules, air bubbles, or polysorbate 20 (PS20) micelles might nucleate cavitation, a high-speed video camera was used to detect cavitation in vials containing antibody formulations after application of controlled mechanical shock using a shock test. Higher concentrations of subvisible particles were found in formulations where cavitation had occurred. Bubbles trapped on vial surfaces were a primary site for cavitation nucleation; other potential cavitation nuclei were ineffective. The incidence of cavitation events observed after application of mechanical shock was lower in type I glass vials than in cyclic olefin polymer vials or in SiOPlas™ cyclic olefin polymer vials and correlated with the surface roughness of the different vials. To reduce the incidence of cavitation and the adsorption of mAb on glass-water and silicone oil-water interfaces and thus minimize protein damage due to cavitation, PS20, a common nonionic surfactant, was added to formulations. Addition of PS20 to formulations in glass and silicone oil-coated glass vials significantly reduced both incidence of mechanical shock-induced cavitation and the particle formation that resulted from cavitation events.


Subject(s)
Polysorbates , Proteins , Adsorption , Glass
4.
Am J Surg ; 218(4): 716-721, 2019 10.
Article in English | MEDLINE | ID: mdl-31350004

ABSTRACT

BACKGROUND: We implemented a protocol to evaluate pediatric patients with suspected appendicitis using ultrasound as the initial imaging modality. CT utilization rates and diagnostic accuracy were evaluated two years after pathway implementation. METHODS: This was a retrospective observational study of patients <18 years evaluated for suspected appendicitis. CT rates were compared before and after implementation of the protocol, and monthly CT rates were calculated to assess trends in CT utilization. RESULTS: CT use decreased significantly following pathway implementation from 94.2% (130/138) to 27.5% (78/284; p < 0.001). Linear regression of monthly CT utilization demonstrated that CT rates continued to trend down two years after pathway implementation. Adherence to the pathway was 89.8% (255/284). Negative appendectomy rate was 2.4% (2/85) in the post-pathway period. CONCLUSIONS: Adherence to a pathway designed to evaluate pediatric patients with suspected appendicitis using ultrasound as the primary imaging modality has led to a sustained decrease in CT use without compromising diagnostic accuracy.


Subject(s)
Appendicitis/diagnostic imaging , Tomography, X-Ray Computed/statistics & numerical data , Adolescent , Appendectomy , Appendicitis/surgery , Child , Child, Preschool , Clinical Protocols , Critical Pathways , Female , Guideline Adherence , Humans , Male , Procedures and Techniques Utilization , Retrospective Studies , Sensitivity and Specificity , Ultrasonography
5.
Am J Surg ; 217(6): 1099-1101, 2019 06.
Article in English | MEDLINE | ID: mdl-30639131

ABSTRACT

BACKGROUND: Variation exists for postoperative antibiotics in children with complicated appendicitis. We investigated the impact of white blood count (WBC) at discharge on oral antibiotic therapy, abscess rate, and readmission rate. MATERIAL/METHODS: We conducted a two year review of children with complicated appendicitis. In the pre-protocol group, total antibiotic therapy was ten days (IV and oral) and home oral antibiotics at discharge. In the post-protocol group, children with leukocytosis were prescribed oral antibiotics to complete seven days of total antibiotic therapy and children without leukocytosis were not prescribed oral home antibiotics. RESULTS: There was no difference between mean hospital days after operation (3.52 vs. 3.24, p = 0.5111), means days of inpatient intravenous antibiotics (3.13 vs. 2.58, p = 0.5438), post-operative abscess rates (20.7% vs. 19.6%, p = 0.9975), or readmission rate (13.4% vs. 12.4%, p = 1.000). The post-protocol group had a shorter average total antibiotic duration (4.24 vs. 9.52 days, p < 0.001) and were more likely to be discharged without oral antibiotics (71.1% vs 8.5%, p < 0.001). DISCUSSION: Limiting home antibiotics at discharge to children with leukocytosis significantly decreases home antibiotic use.


Subject(s)
Abdominal Abscess/prevention & control , Anti-Bacterial Agents/administration & dosage , Appendectomy , Appendicitis/drug therapy , Leukocytosis/diagnosis , Postoperative Care/methods , Postoperative Complications/prevention & control , Abdominal Abscess/blood , Abdominal Abscess/epidemiology , Abdominal Abscess/etiology , Administration, Oral , Adolescent , Anti-Bacterial Agents/therapeutic use , Appendicitis/blood , Appendicitis/complications , Appendicitis/surgery , Child , Child, Preschool , Combined Modality Therapy , Drug Administration Schedule , Female , Humans , Leukocyte Count , Leukocytosis/blood , Leukocytosis/etiology , Male , Patient Discharge , Patient Readmission/statistics & numerical data , Postoperative Complications/blood , Postoperative Complications/epidemiology , Retrospective Studies , Treatment Outcome
6.
J Pediatr Surg ; 54(4): 628-630, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30017066

ABSTRACT

PURPOSE: The low perioperative mortality rate in pediatric surgery precludes effective analysis of mortality at individual institutions. Therefore, analysis of multi-institutional data is essential to determine any patterns of perioperative death in children. The aim of this study was to determine diagnoses associated with 24-hour and 30-day perioperative mortality. METHODS: A retrospective review of the 2012-2015 Pediatric Participant Use Data File (PUF) was performed. Statistical comparisons were made between survivors and nonsurvivors and between those with 24-hour and 30-day mortality using Fischer's exact tests. P-values ≤ 0.05 were considered significant. RESULTS: 103,444 patients who underwent a pediatric surgical operation were evaluated. There were 732 deaths with a 30-day perioperative mortality of 0.7% (732/103,444). Necrotizing enterocolitis (NEC) was the diagnosis associated with the highest 30-day perioperative mortality (175/901, 19%). A significantly higher proportion NEC deaths occurred in the first 24 hours (67% (118/175) vs 33% (57/175) 30 day mortality, p<0.001). Compared to patients who survived following operation for NEC, those who died were statistically more likely to require inotropic support (56% vs. 15%, p<0.001), be diagnosed with sepsis (52% vs. 22%, p < 0.001), and undergo blood transfusion within 48 hours of operation (49% vs. 34%, p<0.001). CONCLUSION: Although the overall pediatric surgical operative mortality rate is low, the largest proportion of perioperative deaths occur secondary to NEC. Based on the high immediate mortality, optimization of operative care for septic patients with NEC should be targeted. TYPE OF STUDY: Prognosis Study LEVEL OF EVIDENCE: Level II.


Subject(s)
Perioperative Period/mortality , Surgical Procedures, Operative/mortality , Adolescent , Child , Child, Preschool , Humans , Infant , Infant, Newborn , Prognosis , Retrospective Studies , Risk Factors , Survival Rate , Survivors , Time Factors
7.
J Pediatr Surg ; 53(11): 2279-2289, 2018 Nov.
Article in English | MEDLINE | ID: mdl-29807830

ABSTRACT

PURPOSE: Pediatric surgeon performed bedside ultrasound (PSPBUS) is a targeted examination that is diagnostic or therapeutic. The aim of this paper is to review literature involving PSPBUS. METHODS: PSPBUS practices reviewed in this paper include central venous catheter placement, physiologic assessment (volume status and echocardiography), hypertrophic pyloric stenosis diagnosis, appendicitis diagnosis, the Focused Assessment with Sonography for Trauma (FAST), thoracic evaluation, and soft tissue infection evaluation. RESULTS: There are no standards for the practice of PSPBUS. CONCLUSIONS: As the role of the pediatric surgeon continues to evolve, PSPBUS will influence practice patterns, disease diagnosis, and patient management. TYPE OF STUDY: Review Article. LEVEL OF EVIDENCE: Level III.


Subject(s)
Point-of-Care Systems , Surgeons , Ultrasonography , Appendicitis/diagnostic imaging , Catheterization, Central Venous/methods , Child , Humans , Pyloric Stenosis, Hypertrophic/diagnostic imaging
8.
J Clin Monit Comput ; 32(6): 1149-1153, 2018 12.
Article in English | MEDLINE | ID: mdl-29511972

ABSTRACT

The purpose of this technological notes paper is to describe our institution's experience collecting peripheral venous pressure (PVP) waveforms using a standard peripheral intravenous catheter in an awake pediatric patient. PVP waveforms were collected from patients with hypertrophic pyloric stenosis. PVP measurements were obtained prospectively at two time points during the hospitalization: admission to emergency department and after bolus in emergency department. Data was collected from thirty-two patients. Interference in the PVP waveforms data collection was associated with the following: patient or device motion, system set-up error, type of IV catheter, and peripheral intravenous catheter location. PVP waveforms can be collected in an awake pediatric patient and adjuncts to decrease signal interference can be used to optimize data collection.


Subject(s)
Blood Pressure Determination/statistics & numerical data , Venous Pressure/physiology , Wavelet Analysis , Catheterization, Peripheral , Dehydration/diagnosis , Dehydration/etiology , Dehydration/therapy , Female , Fluid Therapy , Hemodynamic Monitoring/statistics & numerical data , Humans , Infant , Male , Pilot Projects , Prospective Studies , Pyloric Stenosis, Hypertrophic/complications , Pyloric Stenosis, Hypertrophic/physiopathology , Wakefulness/physiology
9.
J Trauma Acute Care Surg ; 84(5): 758-761, 2018 05.
Article in English | MEDLINE | ID: mdl-29334567

ABSTRACT

BACKGROUND: Variation exists in pediatric vascular trauma management. We aim to determine practice patterns for vascular trauma management at American College of Surgeons verified pediatric trauma centers and evaluate the resources available for management of vascular trauma at both freestanding children's hospitals (FSCH) and pediatric hospitals within general adult hospitals. METHODS: Pediatric surgeons and trauma medical directors at American College of Surgeons designated pediatric surgery trauma centers completed a survey designed to evaluate anticipated management of traumatic arterial injuries and resource availability. Hospital setting comparisons were made using Fisher exact tests and t tests. Binomial tests were used to compare pediatric and vascular surgeons' responses to clinical vignettes. p Values of 0.05 or less were significant. RESULTS: One hundred seventy-six (42%) of 414 pediatric surgeons participated. Vascular surgeons are more likely to operatively manage vascular trauma at all anatomic sites except subclavian artery when compared to pediatric surgeons, regardless of hospital setting (p <0.001). Forty-eight percent of the pediatric trauma medical directors completed their portion of the survey. At FSCHs, 36% did not have a fellowship-trained vascular surgeon on-call schedule, 27% did not have endovascular capabilities, and 18% did not have a radiology technologist always available. CONCLUSION: Vascular surgeons are more likely to manage pediatric vascular trauma regardless of hospital setting. However, FSCH have fewer resources available to provide optimal care. LEVEL OF EVIDENCE: Care management, level IV.


Subject(s)
Clinical Competence , Education, Medical, Graduate/methods , Hospitals, Pediatric/organization & administration , Trauma Centers/organization & administration , Traumatology/education , Vascular Surgical Procedures/education , Vascular System Injuries/surgery , Child , Humans , United States
10.
Pediatr Surg Int ; 34(3): 331-333, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29214341

ABSTRACT

PURPOSE: Classical slipping rib syndrome (SRS) can be subclassified based on anatomical location. We describe our experience with three patients suffering from symptomatic sternocostal slipping rib syndrome (SCSRS), a much less common variant of SRS. METHODS: This was a retrospective review of patients with SRS from 1988 to 2016. Described is our experience. RESULTS: Of 44 patients identified with SRS, three patients underwent operations for SCSRS variant. All three had significant pain and point tenderness at the sternocostal junction, and all experienced a popping sensation localized to this area. The mean age at onset was 14.3 years and mean time to diagnosis was 1.3 years. All patients experienced total resolution of symptoms following localized excision of the offending cartilage. CONCLUSIONS: A high index of suspicion based on history and physical examination are key to the early diagnosis of SCSRS. Excision of the symptomatic cartilage is effective for treatment.


Subject(s)
Chest Pain/etiology , Costal Cartilage/physiopathology , Ligaments/physiopathology , Ribs/physiopathology , Adolescent , Costal Cartilage/surgery , Female , Humans , Ligaments/surgery , Male , Retrospective Studies , Ribs/surgery , Syndrome
11.
J Pediatr Surg ; 52(11): 1751-1754, 2017 Nov.
Article in English | MEDLINE | ID: mdl-28408077

ABSTRACT

BACKGROUND: There is no consensus on optimal timing of gastroschisis repair. The 2012-2014 ACS NSQIP Pediatric Participant Use Data File was used to compare outcomes of primary versus staged gastroschisis repair. METHODS: Cases were divided into primary repair (0-1day) and staged repair (4-14days). Baseline characteristics and outcomes were compared for primary versus staged closure using Fisher's exact tests for categorical variables and Wilcoxon rank-sum tests for continuous variables. Length of stay was compared after controlling for prematurity. RESULTS: There were 627 subjects included, with 364 neonates in the primary group and 263 in the staged group. The primary group demonstrated shorter hospital length of stay (LOS) (5.1days; p<0.001) and had less surgical site infections (OR=0.27; p=0.003), but had longer ventilator days (1.9days; p<0.001). Neonates in the primary repair group were less likely to be discharged home versus transferred to another hospital (OR=0.24; p=0.006) and more likely to require nutritional support at discharge (OR=1.74; p=0.034). No significant differences were identified for mortality, readmissions, postoperative LOS, sepsis or other outcomes. CONCLUSION: Staged repair of gastroschisis has longer LOS attributed to preoperative timing, but less ventilator days. Outcomes for these closure techniques are equivocal and support surgeons performing the closure technique they are most experienced with. LEVEL OF EVIDENCE: III (Treatment: retrospective comparative study).


Subject(s)
Digestive System Surgical Procedures/methods , Gastroschisis/surgery , Analysis of Variance , Datasets as Topic , Digestive System Surgical Procedures/adverse effects , Female , Humans , Infant, Low Birth Weight , Infant, Newborn , Infant, Premature, Diseases , Length of Stay , Male , Respiration, Artificial , Retrospective Studies , Statistics, Nonparametric , Surgical Wound Infection , Time-to-Treatment , Treatment Outcome
12.
Am J Surg ; 214(2): 336-340, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28277233

ABSTRACT

BACKGROUND: There is no required competency for pediatric vascular injury in surgical training. We sought to describe changes over time for surgical specialists operating on pediatric vascular trauma injuries at a pediatric trauma center. METHODS: Charts were retrospectively reviewed for vascular trauma injuries at a freestanding children's hospital between 1993 and 2015. Data were collected on mechanism, injured vessel(s), operation(s) performed, and specialists performing operation. Surgical specialists were compared over time. RESULTS: Ninety-four patients (median age = 12) underwent 101 pediatric vascular trauma operations. There were significant differences in frequency of types of operations (primary repairs, graft repairs, and ligations) performed by pediatric, vascular, and orthopedic surgeons (P < .001). The proportion of operations performed by vascular surgeons increased and those performed by pediatric surgeons decreased significantly over time. CONCLUSIONS: Various surgical specialists manage pediatric vascular trauma. With expansion of integrated residency programs, surgical specialists managing these patients in the future should be trained in both pediatric and vascular surgery.


Subject(s)
Internship and Residency , Pediatrics/education , Specialties, Surgical/education , Vascular System Injuries/surgery , Adolescent , Child , Child, Preschool , Female , Health Services Needs and Demand/statistics & numerical data , Humans , Infant , Male , Retrospective Studies , United States , Young Adult
13.
J Pediatr Surg ; 52(5): 715-717, 2017 May.
Article in English | MEDLINE | ID: mdl-28185628

ABSTRACT

BACKGROUND: Optimal timing to begin feeds in neonates with gastroschisis remains unclear. We examined if bedside abdominal ultrasound for intestinal motility is a feasible tool to detect return of bowel function in neonates with gastroschisis. METHODS: Neonates born with uncomplicated gastroschisis who underwent closure received daily ultrasound exams. Full motility was defined as peristalsis seen in all quadrants. Average length of time between abdominal wall closure and start of enteral feeds, full ultrasound motility, and clinical characteristics was compared using Student's t-tests. RESULTS: Seventeen patients were enrolled. No differences were found between motility on ultrasound and bowel movements, gastric residuals, or nonbilious residuals. Mean time to enteral feeds (11.82days) was significantly delayed compared to documentation of full motility on ultrasound (8.94days; p=0.012), consistent bowel movements (8.41days; p=0.006), low gastric residuals (9.47days; p<0.001), and nonbilious residuals (9.18days; p<0.001). In the single subject in which feeds were started before full motility was seen on ultrasound, feeds were subsequently discontinued because of emesis. CONCLUSION: Bedside abdominal ultrasound provides real-time evidence regarding intestinal motility and is a feasible tool to detect return of bowel function in neonates with gastroschisis. Future studies are needed to determine if abdominal ultrasound can shorten time to start of enteral feeds. LEVEL OF EVIDENCE: III (diagnosis: nonconsecutive study).


Subject(s)
Gastrointestinal Motility , Gastroschisis/diagnostic imaging , Point-of-Care Testing , Postoperative Care/methods , Enteral Nutrition , Feasibility Studies , Female , Gastroschisis/physiopathology , Gastroschisis/surgery , Gastroschisis/therapy , Humans , Infant, Newborn , Male , Postoperative Care/instrumentation , Prospective Studies , Treatment Outcome , Ultrasonography/instrumentation
14.
J Surg Res ; 202(1): 126-31, 2016 May 01.
Article in English | MEDLINE | ID: mdl-27083958

ABSTRACT

BACKGROUND: No consensus has been reached on optimal timing for performing appendectomies. We compared immediate and delayed appendectomies in pediatric patients presenting with suspected acute appendicitis to determine differences in postsurgical complications and perforation rates. METHODS: A retrospective cohort study was performed of all children who underwent appendectomy during a 4-y period. Cutoffs used were 6, 8, and 12 h from admission to operating room (OR). The Student t-tests and chi-square tests were performed to compare continuous and categorical variables, respectively. A logistic regression model was fitted to determine predictors of appendiceal perforation. P values <0.05 were considered significant. RESULTS: Analysis included 484 patients with mean elapsed time from admission to OR of 394 min, with 262 subjects in the immediate and 222 subjects in the delayed >6 h groups. Surgical site infections (SSIs), perforations, and small bowel obstructions were similar between groups, and no statistically significant differences were found for SSIs in the nonperforated delayed versus immediate groups (P = 0.964). Time from admission to the OR did not predict perforation (P = 0.921), although white blood cell count at the time of admission was a significant predictor of perforation (odds ratio, 1.08; P < 0.001). CONCLUSIONS: For suspected acute appendicitis, delaying appendectomy after admission for >6 h demonstrated no differences in SSI or perforation rates compared with immediate appendectomy. Waiting to perform an appendectomy until the following day has equal outcomes to immediate surgical procedure and may improve overall quality of patient care by limiting surgeon fatigue.


Subject(s)
Appendectomy/methods , Appendicitis/surgery , Postoperative Complications/etiology , Acute Disease , Adolescent , Appendicitis/pathology , Child , Child, Preschool , Female , Humans , Logistic Models , Male , Postoperative Complications/epidemiology , Retrospective Studies , Time Factors , Treatment Outcome
15.
J Pediatr Surg ; 51(5): 819-21, 2016 May.
Article in English | MEDLINE | ID: mdl-26949143

ABSTRACT

BACKGROUND: Although this issue remains unexamined, pediatric surgeons commonly use simple interrupted suture for bowel anastomosis, as it is thought to improve intestinal growth postoperatively compared to continuous running suture. However, effects on intestinal growth are unclear. We compared intestinal growth using different anastomotic techniques during the postoperative period in young rats. METHODS: Young, growing rats underwent small bowel transection and anastomosis using either simple interrupted or continuous running technique. At 7-weeks postoperatively after a four-fold growth, the anastomotic site was resected. Diameters and burst pressures were measured. RESULTS: Thirteen rats underwent anastomosis with simple interrupted technique and sixteen with continuous running method. No differences were found in body weight at first (102.46 vs 109.75g) or second operations (413.85 vs 430.63g). Neither the diameters (0.69 vs 0.79cm) nor burst pressures were statistically different, although the calculated circumference was smaller in the simple interrupted group (2.18 vs 2.59cm; p=0.03). No ruptures occurred at the anastomotic line. CONCLUSIONS: This pilot study is the first to compare continuous running to simple interrupted intestinal anastomosis in a pediatric model and showed no difference in growth. Adopting continuous running techniques for bowel anastomosis in young children may lead to faster operative time without affecting intestinal growth.


Subject(s)
Intestine, Small/growth & development , Intestine, Small/surgery , Suture Techniques , Anastomosis, Surgical/methods , Animals , Child , Humans , Models, Animal , Operative Time , Pilot Projects , Rats
16.
J Am Coll Surg ; 222(4): 387-94, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26916127

ABSTRACT

BACKGROUND: Both the Medicare (MCR) and Medicaid (MCD) programs turn 50 this year. Medicare has developed a national resource-based payment methodology for physicians' services, with broad input by specialty societies, and MCD payments are set by individual states by various means. STUDY DESIGN: We have conducted the first national comparison of payment methodology of MCD vs MCR for procedures commonly delivered by general surgeons. Using the most recent Centers for Medicare and Medicaid Services' Medicare data for frequency of allowed charges for general surgeons, we selected the most frequently billed procedures and gathered data from the 50 states for MCD and MCR payments. We determined the "Medicaid discount" (MCD payment minus MCR payment) expressed as dollars and percent, as well as dollars paid per relative value of work. RESULTS: We have discovered wide variations in MCD payments among states for the same procedures, demonstrating unexplained "discounts" of MCD payments in relationship to MCR. We found that MCD payments show wide variations across the states, with many states paying far less than MCR for common, essential procedures. CONCLUSIONS: These findings call into question the fairness of MCD reimbursement for general surgery services in the United States. This discount to MCR could act as a disincentive for surgeons to care for some patients, based on the state of residence. These unexplained discounts could have considerable long-term effects for patients dependent on the MCD program. Our study should act as a stimulus for states to examine their payment methodologies to provide more uniform and fairer payments for surgical procedures.


Subject(s)
General Surgery , Medicaid , Medicare , Reimbursement Mechanisms/economics , Surgical Procedures, Operative/economics , Current Procedural Terminology , Humans , United States
17.
Am J Surg ; 210(6): 1051-4; discussion 1054-5, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26460055

ABSTRACT

BACKGROUND: Surgical wound classification (SWC) is a component of surgical site infection risk stratification. Studies have demonstrated that SWC is often incorrectly documented. This study examines the accuracy of SWC after implementation of a multifaceted plan targeted at accurate documentation. METHODS: A reviewer examined operative notes of 8 pediatric operations and determined SWC for each case. This SWC was compared with nurse-documented SWC. Percent agreement pre- and postintervention was compared. Analysis was performed using chi-square and a P value less than .05 was significant. RESULTS: Preintervention concordance was 58% (112/191) and postintervention was 83% (163/199, P = .001). Appendectomy accuracy was 28% and increased to 80% (P = .0005). Fundoplication accuracy increased from 44% to 84% (P = .016) and gastrostomy tube from 56% to 100% (P = .0002). The most accurate operation preintervention was pyloromyotomy and postintervention was gastrostomy tube and inguinal hernia. The least accurate pre- and postintervention was cholecystectomy. CONCLUSION: Implementation of a multifaceted approach improved accuracy of documented SWC.


Subject(s)
Checklist , Documentation/standards , Surgical Procedures, Operative/standards , Surgical Wound Infection/classification , World Health Organization , Child , Humans , Quality Improvement
18.
Pediatr Surg Int ; 31(12): 1165-9, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26433810

ABSTRACT

PURPOSE: Rapid assessment of volume status in children is often difficult. The purpose of this study was to evaluate the feasibility of surgeon-performed ultrasound to assess volume status in patients with hypertrophic pyloric stenosis. METHODS: Ultrasounds were performed on admission and before operation. The diameters of the inferior vena cava (IVC) and aorta (Ao) were measured and IVC/Ao ratios were calculated. Electrolytes were measured on admission and repeated if warranted. Logistic regression was used to associate the clinical outcome, defined as CO2 ≤30 mEq/L, with IVC/Ao ratios. Predictive capacity was estimated from the logistic regression for IVC/Ao ratios. Linear regression was used to estimate associations between CO2 values and IVC/Ao ratios. RESULTS: Thirty-one patients were enrolled. The IVC/Ao ratio is highly associated with actual CO2 values (P < 0.001) and the clinical outcome (P = 0.004). For every 0.05 unit increase in IVC/Ao ratio, predicted CO2 decreased 1.1 units. For every 0.05 unit increase in the IVC/Ao ratio, the odds of having a CO2 ≤30 mEq/L increased 48% [OR = 1.48, 95% CI (1.13,1.94)]. Predictive capacity is maximized at an IVC/Ao ratio of 0.75 as 83.9 % of subjects were correctly classified and specificity and PPV = 100%. CONCLUSIONS: Surgeon-performed ultrasound to determine IVC/Ao ratio is feasible. An IVC/Ao ratio of 0.75 predicted adequate resuscitation.


Subject(s)
Point-of-Care Systems , Pyloric Stenosis, Hypertrophic/diagnostic imaging , Surgeons , Feasibility Studies , Female , Humans , Infant , Infant, Newborn , Male , Sensitivity and Specificity , Ultrasonography
19.
Pediatr Surg Int ; 31(12): 1161-4, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26263874

ABSTRACT

PURPOSE: A study previously performed at our institution demonstrated that surgeon-performed ultrasound (SPUS) was accurate compared to radiology department ultrasound (RDUS) when evaluating children with suspected appendicitis. The purpose of this study was to determine if these results were reproducible and if SPUS decreased time to definitive diagnosis. METHODS: A surgery resident performed examinations and ultrasounds on children with suspected appendicitis. Final diagnosis was confirmed by pathology. Results were compared to RDUS and combined with the previous study for a final comparison with RDUS. Mean time to diagnosis was recorded. Data were analyzed using Fisher exact and Student's t test. RESULTS: Fifty-eight patients underwent SPUS, of these 35 had RDUS. The accuracy of SPUS alone was 93% (54/58) and RDUS accuracy was 94% (33/35) (p = 1). When SPUS was combined with clinical examination accuracy increased to 95% (55/58). When results were combined with the previous study, overall accuracy of SPUS was 90% (101/112) compared to overall RDUS accuracy of 89 % (50/56). Mean time to diagnosis for RDUS was 135 min (n = 35), whereas mean time to diagnosis for SPUS was 30 min (n = 58; p = 0.0001). CONCLUSION: SPUS is accurate and reproducible in evaluating children with suspected appendicitis. SPUS potentially decreases time to definitive therapy and emergency department wait times.


Subject(s)
Appendicitis/diagnostic imaging , Surgeons , Adolescent , Adult , Appendix/diagnostic imaging , Child , Child, Preschool , Diagnosis, Differential , Female , Humans , Infant , Male , Reproducibility of Results , Sensitivity and Specificity , Ultrasonography , Young Adult
20.
J Surg Educ ; 71(6): 896-8, 2014.
Article in English | MEDLINE | ID: mdl-24931414

ABSTRACT

OBJECTIVE: Our institution has demonstrated the diagnostic accuracy of surgeon-performed ultrasound (US) in the diagnosis of hypertrophic pyloric stenosis (HPS). Moreover, we have also shown this modality to be accurate and reproducible through surgeon-to-surgeon instruction. The purpose of this study was to determine whether a surgical resident with experience in diagnosing HPS can teach pediatric emergency medicine (PEM) fellows, with little experience in sonography, to accurately measure the pyloric channel with bedside US. METHODS: A surgical resident with experience in diagnosing HPS with US-proctored 4 emergency medicine fellows for 5 bedside US examinations each. A PEM fellow, who was blinded to the results from the radiology department US, then performed bedside US and measured the pyloric channel in patients presenting to the emergency department with HPS. Results between the radiology department and the fellows were compared using the Student t test. RESULTS: In total, 18 USs were performed on 17 patients. There were no false-negative or false-positive results. There was no statistical difference between the radiology department and fellow measurement when evaluating muscle width (p = 0.21, mean deviation = 0.2 mm) or channel length (p = 0.47, mean deviation = 0.6 mm). CONCLUSION: Bedside-performed US technique for measuring the pylorus length and width in patients with HPS is reproducible and accurate when taught to PEM providers. The learning curve for this technique is short.


Subject(s)
Education, Medical, Graduate , Pediatrics/education , Point-of-Care Systems , Pyloric Stenosis, Hypertrophic/diagnostic imaging , Clinical Competence , Female , Humans , Internship and Residency , Male , Prospective Studies , Ultrasonography
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