ABSTRACT
One case of giant cell tumor located in the mandibular condyle is reported. This case was revealed by a progressive mandibular deviation. Frequency, localization, etiopathogenesis and histological feature are discussed.
Subject(s)
Giant Cell Tumor of Bone/pathology , Mandibular Condyle/pathology , Mandibular Neoplasms/pathology , Adult , Antigens, CD/analysis , Antigens, Differentiation, Myelomonocytic/analysis , Facial Asymmetry/pathology , Giant Cells/pathology , Hemosiderin/analysis , Humans , Male , Osteolysis/pathology , Vimentin/analysisABSTRACT
Dentigerous cysts, also called follicularor corono-dental cysts, are malformative odontogenic cysts in the WHO classification of odontogenic tumors. We review the general characteristics of these frequent odontogenic tumors which always occur in associated with an included tooth. Diagnosis is based on clinical features, X-ray findings and pathology results. We report the evolutive aspect in three patients of different ages.
Subject(s)
Dentigerous Cyst/pathology , Adolescent , Dentigerous Cyst/diagnostic imaging , Dentigerous Cyst/physiopathology , Dentigerous Cyst/surgery , Epithelial Cells/pathology , Humans , Male , Middle Aged , Molar/diagnostic imaging , Molar/pathology , Odontogenic Cysts/classification , Radiography, Panoramic , Tomography, X-Ray Computed , Tooth, Impacted/diagnostic imaging , Tooth, Impacted/pathology , World Health OrganizationABSTRACT
The use of lidocaine HCL solution at concentrations of 0.5 and 1.0% to reconstitute sodium cefoxitin relieves the pain associated with intramuscular injections of the antibiotic. Cefoxitin absorption by the intramuscular route is initially rapid and is virtually complete. Peak serum concentrations, corresponding to about one-half those of a comparable intravenous infusion, are achieved in 30 min. Continuing absorption tends to maintain higher serum concentrations for longer times. Renal clearance and serum half-life of cefoxitin do not appear to be affected by lidocaine at its effective anaesthetic concentrations.
Subject(s)
Cefoxitin/metabolism , Cephalosporins/metabolism , Lidocaine/pharmacology , Absorption , Adult , Cefoxitin/administration & dosage , Cefoxitin/adverse effects , Drug Interactions , Half-Life , Humans , Injections, Intramuscular , Kinetics , Male , Time FactorsABSTRACT
Intravenous doses of 0.5, 1, and 2 g cephalothin and cefoxitin, a semi-synthetic cephamycin antibiotic highly resistant to bacterial cephalosporinase, were infused over a period of 3 minutes into 18 normal adult males by a randomized, crossover design. Serum and urine data on cefoxitin best fit a two-compartment open model. Serum concentrations following cefoxitin were higher and more prolonged and urine recoveries higher than those following equal doses of cephalothin. The terminal serum half-life of cefoxitin was longer at all dose levels. Renal clearance of cephalothin-like activity exceeded that of cefoxitin, which may possess dose-dependent kinetics. Whereas cephalothin has been reported to metabolize by greater than 35% to the less active desacetyl form, cefoxitin was metabolized by 0.1 to 6% to the descarbamyl form in individual subjects.