ABSTRACT
Primary cerebellar glioblastoma multiforme (GBM) is a rare tumor in adults that accounts for just 1% of all cases of GBM. Cerebellar GBMs are not yet completely understood also as far as the prognosis. We report a case of cerebellar GBM in a 27-year-old woman. Magnetic resonance imaging (MRI) showed a 3x3.6 cm-sized, ill-defined, heterogeneously enhancing mass in the left cerebellum. GBM was histologically confirmed following radical surgery. Postoperative radiotherapy with concomitant and adjuvant temozolomide chemotherapy was subsequently administrated. She has no evidence of recurrence and is in good clinical conditions up-to date, three years after surgery.
Subject(s)
Cerebellar Neoplasms/surgery , Glioblastoma/surgery , Adult , Antineoplastic Agents/therapeutic use , Cerebellar Neoplasms/drug therapy , Cerebellar Neoplasms/pathology , Chemotherapy, Adjuvant , Combined Modality Therapy , Dacarbazine/therapeutic use , Female , Glioblastoma/drug therapy , Glioblastoma/pathology , Humans , Treatment OutcomeABSTRACT
A case of a basal middle fossa giant cell tumor occurring in a 46-year-old man is described. The lesion appeared at the computed tomography (CT) scan examination as an hypodense mass with a peripheral "ring-like" enhancement, and no evident erosion of the skull base. The tumor, which infiltrated the basal temporal parenchyma, was removed via a temporal transzygomatic craniotomy, and extensive drilling of the petrous bone. Despite the occurrence of significant postoperative complications, the patient ultimately showed a good clinical outcome, with no signs of recurrence at the 1-year-follow-up CT scanning. The clinical and diagnostic aspects and the management policy of this rare lesion are discussed.