Description of the modes governing the optical transmission through metal gratings.

An analytical model based on a modal expansion method is developed to investigate the optical transmission through metal gratings. This model gives analytical expressions for the transmission as well as for the dispersion relations of the modes responsible for high transmission. These expressions are accurate even for real metals used in the visible - near-infrared wavelength range, where surface plasmon polaritons (SPP's) are excited. The dispersion relations allow the nature of the modes to be assessed. We find that the transmission modes are hybrid between Fabry-Pérot like modes and SPP's. It is also shown that it is important to consider different refractive indices above and below the gratings in order to determine the nature of the hybrid modes. These findings are important as they clarify the nature of the modes responsible for high transmission. It can also be useful as a design tool for metal gratings for various applications.

A beta-scintillator for surface measurements of radiotracer kinetics in the intact rodent cortex.

Beta+-sensitive probes are useful tools for the measurement of radiotracer kinetics in small animals. They allow the cost-effective development of new PET tracers and offer the possibility to investigate a variety of cerebral processes. The study's main aim was the in vivo evaluation of a probe system for cerebral surface acquisitions. The detector system is a 0.2-mm thick scintillating disk of 3-mm diameter, positioned close to the cerebral surface. The study consists of 4 subparts: (1) simulation of the detection volume, (2) direct comparison with the classic intracortical beta probe regarding its capability to acquire kinetic data, (3) test of the ability to detect local tracer accumulations during infraorbital nerve (ION) electrostimulation and (4) demonstration of the feasibility to measure tracer kinetics in awake animals. Kinetic data acquired with 18F-fluorodeoxyglucose and 15O-H2O were fitted with standard compartment models. The surface probe measurements were in good agreement with those obtained using the intracortical scintillator. ION electrostimulation induced a marked increase in tracer accumulation adequately detected by the surface probe. In the head-fixed animal, a marked change in FDG kinetics was detected between the awake and anesthetized state. The novel surface probe system proved to be a valuable instrument for in vivo radiotracer studies of the cerebral cortex. Its main advantage is the absence of any tissue damage. In addition, serial acquisitions of tracer kinetics in the awake animal turned out to be feasible.

Scattering of light by a single layer of randomly packed dielectric microspheres giving color effects in transmission.

Strong scattering properties are obtained for a monolayer of randomly packed polystyrene microspheres. This gives rise to structural colors in transmission. For a sphere diameter between 0.5 and 1 micron, light is mainly scattered in the forward direction. Consequently, in-plane multiple scattering can be neglected when spheres are not too close to each others. This allows one to use a single scattering approximation to reproduce transmission spectra of the system. The film color is dependent on the sphere size, but also on the observation angle. This angular dependant color is reproduced taking into account multiple scattering between spheres. These films can be useful when low reflection is needed.

Optically tunable microcavity in a planar photonic crystal silicon waveguide buried in oxide.

We present all-optical tuning and switching of a microcavity inside a two-dimensional photonic crystal waveguide. The photonic crystal structure is fabricated in silicon-on-insulator using complementary metal-oxide semiconductor processing techniques based on deep ultraviolet lithography and is completely buried in a silicon dioxide cladding that provides protection from the environment. By focusing a laser onto the microcavity region, both a thermal and a plasma dispersion effect are generated, allowing tuning and fast modulation of the in-plane transmission. By means of the temporal characteristics of the in-plane transmission, we experimentally identify a slower thermal and a fast plasma dispersion effect with modulation bandwidths of the order of several 100 kHz and up to the gigahertz level, respectively.

Quantitative cerebral blood flow measurements in the rat using a beta-probe and H2 15O.

Beta-probes are a relatively new tool for tracer kinetic studies in animals. They are highly suited to evaluate new positron emission tomography tracers or measure physiologic parameters at rest and after some kind of stimulation or intervention. In many of these experiments, the knowledge of CBF is highly important. Thus, the purpose of this study was to evaluate the method of CBF measurements using a beta-probe and H2 15O. CBF was measured in the barrel cortex of eight rats at baseline and after acetazolamide challenge. Trigeminal nerve stimulation was additionally performed in five animals. In each category, three injections of 250 to 300 MBq H2 15O were performed at 10-minute intervals. Data were analyzed using a standard one-tissue compartment model (K1 = CBF, k2 = CBF/p, where p is the partition coefficient). Values for K1 were 0.35 +/- 0.09, 0.58 +/- 0.16, and 0.49 +/- 0.03 mL x min(-1) x mL(-1) at rest, after acetazolamide challenge, and during trigeminal nerve stimulation, respectively. The corresponding values for k2 were 0.55 +/- 0.12, 0.94 +/- 0.16, and 0.85 +/- 0.12 min(-7), and for p were 0.64 +/- 0.05, 0.61 +/- 0.07, and 0.59 +/- 0.06. The standard deviation of the difference between two successive experiments, a measure for the reproducibility of the method, was 10.1%, 13.0%, and 5.7% for K1, k2, and p, respectively. In summary, beta-probes in conjunction with H2 15O allow the reproducible quantitative measurement of CBF, although some systematic underestimation seems to occur, probably because of partial volume effects.