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1.
J Med Syst ; 44(9): 168, 2020 Aug 13.
Article in English | MEDLINE | ID: mdl-32789703

ABSTRACT

With increasing economic pressure on health care, modern hospital management is focusing at industrial optimization techniques to improve efficiency while maintaining quality. Shop floor management, a technique of code-based, process-oriented guidance directly on site is a method of lean management intended to increase efficiency in the operating room. In the literature, there is only scant evidence that the introduction of this technique alone can increase efficiency. The aim of this retrospective study is to determine whether a single tool alone can significantly improve codes. We performed an empirical, retrospective analysis of a number of codes from 3800 operations during two periods of comparison: upon introduction of shop floor management, and one year thereafter. Data was extracted from the Hospital Information System and transferred to a database. There was no statistically significant change in the relevant codes chosen, whether specific to the operating room (turnover time, first patient in the room, waiting times for anesthesia and surgery (p = 0.637) or to planning stability (scheduled, cancelled (p = 0.505), unscheduled and total operations performed (p = 0.984)). There were absolute changes, such as a reduction in the turnover time from 17:37 min to 16:26 min, even though not statistically significant (p = 0.238). Implementation of shop floor management as a single intervention is not appropriate to achieve a significant, continuous improvement in codes. A combination with other techniques such as detailed process analyses is definitely required. This could be important additional information for units using Lean Health Care strategies.


Subject(s)
Anesthesiology , Operating Rooms , Efficiency , Efficiency, Organizational , Humans , Retrospective Studies
2.
Br J Anaesth ; 108(2): 229-35, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22157846

ABSTRACT

BACKGROUND: Cognitive errors are thought-process errors, or thinking mistakes, which lead to incorrect diagnoses, treatments, or both. This psychology of decision-making has received little formal attention in anaesthesiology literature, although it is widely appreciated in other safety cultures, such as aviation, and other medical specialities. We sought to identify which types of cognitive errors are most important in anaesthesiology. METHODS: This study consisted of two parts. First, we created a cognitive error catalogue specific to anaesthesiology practice using a literature review, modified Delphi method with experts, and a survey of academic faculty. In the second part, we observed for those cognitive errors during resident physician management of simulated anaesthesiology emergencies. RESULTS: Of >30 described cognitive errors, the modified Delphi method yielded 14 key items experts felt were most important and prevalent in anaesthesiology practice (Table 1). Faculty survey responses narrowed this to a 'top 10' catalogue consisting of anchoring, availability bias, premature closure, feedback bias, framing effect, confirmation bias, omission bias, commission bias, overconfidence, and sunk costs (Table 2). Nine types of cognitive errors were selected for observation during simulated emergency management. Seven of those nine types of cognitive errors occurred in >50% of observed emergencies (Table 3). CONCLUSIONS: Cognitive errors are thought to contribute significantly to medical mishaps. We identified cognitive errors specific to anaesthesiology practice. Understanding the key types of cognitive errors specific to anaesthesiology is the first step towards training in metacognition and de-biasing strategies, which may improve patient safety.


Subject(s)
Anesthesia/standards , Anesthesiology/standards , Cognition , Medical Errors/psychology , California , Clinical Competence , Decision Making , Delphi Technique , Emergencies , Humans , Medical Errors/prevention & control , Patient Simulation , Pilot Projects
3.
Head Neck Pathol ; 4(3): 257-60, 2010 Sep.
Article in English | MEDLINE | ID: mdl-20625862

ABSTRACT

Synovial sarcoma (SS), 3-5% of which occurs in the head and neck region, has generally been regarded as high grade sarcoma. Recent analysis of clinical, morphological, and molecular characteristics of SS, however, identified low and high risk group of patients, resulting in important implications for the treatment of patients diagnosed with SS. We describe the case of a 31-year-old male who presented with biphasic SS with poorly differentiated areas (clinical stage IIA) in a palatine tonsil, an extremely rare site of SS. Molecular analyses revealed typical t(X;18) translocation of the SYT gene and a SYT/SSX1 fusion type. The tumor was surgically resected with free margins. Adjuvant radiotherapy or chemotherapy was not considered indicated. To date, the patient has remained free of tumor for 4 years after surgery. Literature review reveals that primary tonsillar HNSS has previously been documented only in three patients. In all of these patients the tumor was histologically biphasic; however only one published case and the case presented here showed areas of poor differentiation. We discuss the relevance of the presented findings with regard to prognostic and therapeutic considerations in SS in the head and neck region.


Subject(s)
Sarcoma, Synovial/pathology , Tonsillar Neoplasms/pathology , Adult , Biomarkers, Tumor/metabolism , Disease-Free Survival , Humans , Male , Neoplasm Proteins/genetics , Neoplasm Proteins/metabolism , Neoplasm Staging , Oncogene Proteins, Fusion/genetics , Oncogene Proteins, Fusion/metabolism , Proto-Oncogene Proteins/genetics , Proto-Oncogene Proteins/metabolism , Repressor Proteins/genetics , Repressor Proteins/metabolism , Sarcoma, Synovial/genetics , Sarcoma, Synovial/surgery , Tonsillar Neoplasms/genetics , Tonsillar Neoplasms/surgery , Translocation, Genetic
5.
Eur Psychiatry ; 20(8): 554-8, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16140510

ABSTRACT

PURPOSE: We assessed the quality of European treatment guidelines in the field of mental health that have been produced by national psychiatric associations. The main focus was the question of whether the development process of the guidelines followed basic principles of evidence-based medicine. METHODS: Sixty-one European clinical practice guidelines from 14 countries, published between 1998 and 2003, were assessed using the 'Appraisal of Guidelines for Research and Evaluation (AGREE) Instrument'. The domain score was calculated for each of the six domains of the AGREE instrument. The seven items of the domain "rigor of development" and one additional item concerning national particularities were assessed in detail. RESULTS: The mean scores in the six domains were rather low, although the quality varied among the different guidelines. The highest mean score was obtained in the domain clarity and presentation (70.8% S.D. 23.5), the lowest on editorial independence (19.7% S.D. 29.3). The recommendations of about half of the assessed guidelines could be considered to be evidence-based. CONCLUSION: The assessed guidelines showed a broad range of quality: some producers attached importance to an evidence-based development process; but in spite of this, a large number of guidelines were only of middling quality. As national particularities are only rarely mentioned and the development process of guidelines is complex, an international collaboration that aims toward the production of shareable guidelines might be promising.


Subject(s)
Mental Disorders/therapy , Mental Health Services/standards , Practice Guidelines as Topic , Europe , Evidence-Based Medicine , Humans
6.
Ultraschall Med ; 26(2): 142-5, 2005 Apr.
Article in English | MEDLINE | ID: mdl-15852178

ABSTRACT

OBJECTIVES: Since 1990 percutaneous ethanol injection therapy (PEIT) has been applied clinically as a treatment strategy for focal and diffuse autonomy of the thyroid, for cystic lesions and for ablation of parathyroid hyperplasia (PEA). There are some additional indications currently under consideration as for example inoperable advanced cancer of the thyroid. Since its inception PEIT and PEA have been regarded as an effective, inexpensive and low risk procedure. MATERIAL AND METHODS: We discuss mild and severe complications of these methods reported in literature and the first case so far of a severe ethyl toxic necrosis of the larynx and adjacent skin in a patient treated with PEIT by a radiologist. RESULTS: To date, no serious side effects have been reported in connection with these therapies. Some authors conclude that the side effects are in no way negligible and caution and routine should be exercised when using PEIT or PEA. Most complications have been transient in nature. The complication of ethyl toxic necrosis of the larynx was serious and the patient was admitted to hospital, treated conservatively and ten month later microsurgically. Voice thus could be restored to almost normal. CONCLUSIONS: PEIT for focal and diffuse autonomy, for cystic lesions of the thyroid, for thyroid hyperplasia and PEA for parathyroid hyperplasia are methods which are inexpensive and can be performed on an ambulatory base. These are the methods of choice if surgical intervention or radioiodine therapies are not practicable out of medical reasons or by refusal of the patient. The patient must be informed about possible severe complications. The examiner should have substantial experience in these methods. If complications an early opinion of a specialist is required.


Subject(s)
Adenoma/diagnostic imaging , Ethanol/therapeutic use , Injections, Jet/methods , Parathyroid Diseases/diagnostic imaging , Skin/ultrastructure , Thyroid Neoplasms/diagnostic imaging , Adenoma/drug therapy , Ethanol/administration & dosage , Humans , Hyperplasia , Parathyroid Diseases/drug therapy , Thyroid Neoplasms/drug therapy , Treatment Outcome , Ultrasonography , Voice Disorders/diagnostic imaging , Voice Disorders/drug therapy , Voice Disorders/etiology
8.
Eur J Clin Invest ; 31(3): 234-9, 2001 Mar.
Article in English | MEDLINE | ID: mdl-11264651

ABSTRACT

The role of nitric oxide (NO) in the pathophysiology of inflammatory bowel diseases (IBD) is controversially discussed. The aim of the present study was to investigate the role of NO inhibition in the acute phase of rat 2,4,6-trinitrobenzenesulphonic acid (TNB)-colitis. To inhibit NO synthesis we used aminoguanidine (AG) as a selective inhibitor of inducible nitric oxide synthase (iNOS). TNB-colitis was induced in rats with and without pretreatment with AG (200 mg kg-1 body weight in the drinking water). The severity of colitis was observed over a period of 7 days. On days 1 and 2, AG reduced concentrations of plasma nitrate and nitrite as well as of portal 6-keto-prostaglandin 1alpha. AG pretreatment increased colonic damage and inflammatory response, assessed by colonic myeloperoxidase and serum lactate dehydrogenase activity, macroscopic damage score, tumour necrosis factor-alpha concentration in stool and colonic glutathione content. The AG-treated group showed a higher and prolonged nuclear factor kappaB (NF-kappaB)/Rel binding activity in the colon. We conclude that NOS inhibition by AG is not beneficial in acute intestinal inflammation. With regard to appropriate therapeutic strategies, NF-kappaB/Rel activation might be a more suitable target.


Subject(s)
Colitis/enzymology , Colitis/pathology , Colon/drug effects , Colon/pathology , Guanidines/pharmacology , Nitric Oxide/antagonists & inhibitors , Nitric Oxide/biosynthesis , Trinitrobenzenesulfonic Acid , Acute Disease , Animals , Colitis/chemically induced , Colitis/metabolism , Colon/metabolism , Liver/metabolism , Male , NF-kappa B/metabolism , Neutrophil Infiltration/drug effects , Nitric Oxide/metabolism , Prostaglandins/metabolism , Proto-Oncogene Proteins/metabolism , Rats , Rats, Wistar , Transcription Factor RelB , Transcription Factors/metabolism , Up-Regulation/drug effects
9.
Phys Sportsmed ; 18(9): 32-8, 1990 Sep.
Article in English | MEDLINE | ID: mdl-27447581

ABSTRACT

A Forum for Our Readers Jim Blankenship, MD Danville, Pennsylvania Forum is intended to provide a sounding board for our readers. Perhaps you have a special way to treat a common medical problem, or you may want to air your views on a controversial topic. You may object to an article that we have published, or you may want to support one. You may have a new trend to report, identified through an interesting case or a series of patients. Whatever your ideas, we invite you to send them to us. Illustrative figures are welcomed. Address correspondence to Forum, THE PHYSICIAN AND SPORTSMEDICINE, 4530 W 77th St, Minneapolis, MN 55435.

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