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1.
Eur J Med Res ; 28(1): 407, 2023 Oct 07.
Article in English | MEDLINE | ID: mdl-37805504

ABSTRACT

BACKGROUND: Minimally Invasive Tissue Sampling (MITS) has been successfully used to establish the cause of death in low- and middle-income countries, mostly in stillbirths and neonates. The objective of this study was to determine the causes of death among adults using MITS in the Gandaki province of Nepal and to find out the contribution of MITS to identify the causes of death. METHODS: A multicentric hospital-based pilot study was conducted to enroll 100 cases of adult deaths. The specimens of cerebrospinal fluid, blood, brain, lungs, and liver tissue were collected utilizing MITS. These specimens underwent standard histopathological, serological, and microbiological analyses. The findings from MITS, and if available, clinical records and forensic autopsy findings were compiled and the cause of death panel identified the causes of death. The final cause of death allocated to each case was based on the WHO International Medical Certificate of Death. RESULTS: Among a total of 100 cases enrolled during the study period, infectious cause attributed to the immediate cause of death in 77 (77%), cardiovascular in 10 (10%), neurological in 8 (8%), malignancy in two (2%), and gastrointestinal and hepatobiliary cause in one (1%) case. The mean age of the cases was 50.8 ± 15.9 years and 76 (76%) were males. MITS established the cause of death in the causal chain of events in 81(81%) cases and identified the cause of death significantly more with infectious than non-infectious causes (p < 0.001). CONCLUSIONS: MITS was useful in establishing the cause of death in the majority of adult deaths and the most common cause was infectious disease. Our findings suggest that MITS can be a valuable and alternative tool for mortality surveillance in low-resource settings, where complete diagnostic autopsies are less accepted or less prioritized.


Subject(s)
Stillbirth , Infant, Newborn , Male , Pregnancy , Female , Humans , Adult , Middle Aged , Aged , Pilot Projects , Nepal/epidemiology , Cause of Death , Autopsy
2.
PLoS One ; 18(10): e0291265, 2023.
Article in English | MEDLINE | ID: mdl-37862336

ABSTRACT

INTRODUCTION: Bronchial asthma continues to be a problem in the Himalayan country of Nepal. This study explored the impact of bronchial asthma on patients' lives in a hill village in Syangja district, Nepal, and obtained information about the perceived impact of the illness, knowledge of the disease, self-care behaviors and treatment among patients. MATERIAL AND METHODS: The study site is the village of Jyamire (located at an elevation between 900 to 1200 m) Syangja district. Individuals suffering from asthma residing in the village aged 18 years or above were included. Semi-structured interviews were conducted face-to-face with the respondents at their homes using an interview guide. The interviews were audio recorded, transcribed in the Nepali language, and then translated into English for further analysis. RESULTS: Most participants were female, between 18 to 60 years of age, and housewives. Most houses were built of mud and poorly ventilated. Gas was used for cooking though firewood was also used. Most used to get an average of three serious attacks a year both during winter and summer. The themes that emerged were the number and seasonal variation in attacks, the perceived effect of asthma on their lives and social interactions, the knowledge of the interviewee about the disease, the impact of asthma on their socioeconomic status, and treatment and self-care behaviors. Residing in a hill village required them to walk up and down several times a day and the disease seriously impacted their lives. The smoke produced during different ceremonies and during cooking also worsened their asthma. CONCLUSION: Findings suggest, the existence of multiple factors, a few unique to Nepal contributing to poor asthma control. Though the recent socioeconomic improvement has led to improved prevention and treatment options, asthma seriously affected the patients.


Subject(s)
Asthma , Humans , Female , Male , Nepal/epidemiology , Qualitative Research , Asthma/epidemiology , Asthma/therapy , Smoke
3.
SAGE Open Med Case Rep ; 11: 2050313X231157985, 2023.
Article in English | MEDLINE | ID: mdl-36860306

ABSTRACT

Locally prepared liquor, which is not standardized or regulated, though cheap can contain various toxic ingredients and even may be fatal. We report a case series of four adult males who died within 18.5 h due to the effect of local liquor consumption in a hilly district of Gandaki Province of Nepal. Methanol toxicity due to illicitly produced alcohol consumption should be managed with adequate supportive care and administration of specific antidotes such as ethanol or fomepizole. Liquor production should be standardized, and quality checks should be done before the sale for consumption.

4.
J Med Case Rep ; 17(1): 43, 2023 Feb 11.
Article in English | MEDLINE | ID: mdl-36765404

ABSTRACT

BACKGROUND: Imidacloprid, a neonicotinoid insecticide, is widely used in agricultural settings. Consequently, cases of accidental and suicidal poisoning are increasingly seen in clinical practice. Although cases with varied clinical presentations and toxicological profiles have been reported, standard management principles are lacking. CASE PRESENTATION: We present a case of Imidacloprid poisoning in a 25-year-old previously healthy indigenous Tamang female without a classic toxidrome requiring ventilatory support, complicated by a prolonged neuropsychiatric sequela. CONCLUSIONS: Although uncommonly reported, imidacloprid toxicity may lead to life-threatening complications and hence should be suspected in cases of unidentified poisoning with a relevant toxidrome. Vigilance on the part of treating physicians plays a crucial role in appropriate management.


Subject(s)
Insecticides , Female , Humans , Adult , Neonicotinoids , Nitro Compounds
5.
Dev World Bioeth ; 23(3): 285-292, 2023 09.
Article in English | MEDLINE | ID: mdl-36170150

ABSTRACT

In Nepal, live donor organ transplantation is only 14 years old with the first successful kidney transplant made in 2008 and a successful liver and bone marrow transplant made in 2016. However, transplantation of cadaveric cornea dates back to 1998. There are still no cases of animal-to-human organ transplantation in Nepal. There are stringent laws to regulate human body organ transplantation in Nepal which are amended from time to time. However, there is a racket of human traffickers who lure rural people from this low-income country into the illegal organ trade. Furthermore, there is a substantial lack of awareness of organ donation among the general public. This article focuses on the stipulations of ethical, legal, and practical issues of obtaining organs procured from living and brain-dead donors that support the process of transplantation in Nepal. In addition, the article also explores the legal and practical issues of organ trafficking and organ donation awareness in Nepal on the basis of factual data and findings from other studies.


Subject(s)
Kidney Transplantation , Organ Transplantation , Tissue and Organ Procurement , Humans , Adolescent , Nepal , Living Donors
6.
J Nepal Health Res Counc ; 20(2): 412-418, 2022 Nov 02.
Article in English | MEDLINE | ID: mdl-36550721

ABSTRACT

BACKGROUND: The females in the reproductive age group are vulnerable to injuries and diseases. There is no reliable evidence of the pattern of deaths in reproductive age group females from Nepal. This study was conducted to explore the patterns of deaths of females of the reproductive age group in Nepal. METHODS: A multicentric quantitative cross-sectional study was conducted among the 611 deceased females of age 15 to 49 years who had undergone medico-legal autopsy in major autopsy centers of the capital cities of seven provinces of Nepal in a duration of one year. The demographic, clinical, and causes of death data were retrieved from the records and analyzed. The intentional and unintentional causes were compared with the marital status, age groups, ethnicity, and deceased of rural and urban communities. RESULTS: Female reproductive age group deaths constituted 611 (20·64%) of the total autopsies. Suicide was the most common manner of death (413, 67·59%) followed by accident (121, 19·80%). The most common cause of suicide was hanging (258, 62·47%) followed by poisoning (149, 36·08%) whereas road traffic accident (72, 59·5%) was the commonest cause of accidental death. Intentional deaths were associated with higher risk to the females of younger age groups (p<0·001), ethnicity of the hilly region (p<0·001), and unmarried women (p=0·001). CONCLUSIONS: Suicide was the commonest manner of death among the autopsies of females of the reproductive age group in Nepal. Appropriate preventive strategies need to be developed to uplift the overall health, socioeconomic status, and general wellbeing of the females.


Subject(s)
Accidents , Suicide , Humans , Female , Adolescent , Young Adult , Adult , Middle Aged , Autopsy , Cities , Nepal/epidemiology , Cross-Sectional Studies , Cause of Death
7.
BMC Med Educ ; 22(1): 766, 2022 Nov 08.
Article in English | MEDLINE | ID: mdl-36348392

ABSTRACT

BACKGROUND: The effectiveness of online classes is always a concern, and it can be overcome by opting for active learning strategies like team-based learning (TBL). This study was conducted to find out the effectiveness of online TBL as an active learning strategy. We also aimed to explore the satisfaction and perception of students toward TBL. METHODS: This is a mixed-method study conducted among 29 third-year Bachelor of Medicine and Bachelor of Surgery (MBBS) students of Gandaki Medical College using purposive sampling method in the duration of January to September 2021. Three two hours online TBL sessions were used for teaching introduction to medical ethics. The individual readiness assurance test (IRAT) scores were compared to the group readiness assurance test (GRAT) scores to evaluate the effect of TBL through cooperative learning. Learner reactions and satisfaction of students towards TBL were assessed using a validated questionnaire comprising of a five-point Likert scale. An open-ended question asking the participants to describe their overall experience of the TBL sessions was also included to explore their perceptions towards TBL. The data were collected using Google form and exported to Microsoft Excel and the quantitative data were then analyzed using Statistical Package for Social Sciences (SPSS) version 16.0. To check the normal distribution of the data, Kolmogorov Smirnov and Shapiro-Wilk test were used. Non-parametric tests were used for the non-normally distributed data. P value of < 0.05 was regarded as significant. Thematic analysis was conducted for the qualitative data. RESULTS: The median GRAT scores were significantly higher (p = 0.006 in TBL 1 and 0.001 in TBL 2) than IRAT scores. Learner reactions toward TBL sessions were positive as shown by the mean scores which were in the range of 3.59 to 4.66. Five themes were generated from the codes: "effective learning method", "positive experience", "gained knowledge", "expression of gratitude" and "the way of conduction of the sessions". CONCLUSION: Online TBL in medical ethics was effective as a teaching learning tool in our setting. The students were satisfied with the learning process and rated the learning strategy positively.


Subject(s)
Students, Medical , Humans , Educational Measurement/methods , Ethics, Medical/education , Group Processes , Nepal , Pilot Projects , Problem-Based Learning/methods
8.
BMC Pregnancy Childbirth ; 22(1): 245, 2022 Mar 24.
Article in English | MEDLINE | ID: mdl-35331187

ABSTRACT

BACKGROUND: Perinatal and neonatal death rates have decreased recently but it still poses a major challenge to the health system of Nepal. The study was conducted to explore the pattern and causes of perinatal deaths. METHODS: This was a descriptive cross-sectional study conducted from September 2020 to June 2021 using the data of perinatal mortality of three years from June 15, 2017, to June 14, 2020. The demographic parameters of the mother consisted of maternal age, place of residence, ethnicity, antenatal care, the number of antenatal visits, gravida, gestational weeks, and the mode of delivery. The causes of death were categorized into fetal and early neonatal deaths. Fetal deaths were further classified as macerated stillbirth and fresh stillbirth. The attribution of the causes of deaths to fetal/neonatal and maternal conditions was done as per the guidelines of the WHO application of ICD-10 to deaths during the perinatal period. RESULTS: There were a total of 145 perinatal deaths from 144 mothers among which 92 (63.5%) were males. Ten mothers (6.9%) had not sought even single antenatal care, whereas 32 (22.9%) had visited for antenatal care one to three times. At least one cause of death was identified in 114 (78.6%) and remained unknown in 31(21.4%) cases. Among the 28 cases of macerated stillbirths, the cause of death was not identified in 14 (50%), whereas preterm labor was attributed to the cause of death in four (14.3%). In 53 of the fresh stillbirths, intrapartum hypoxia was identified as the cause of death in 20 (37.7%) cases, preterm labor in nine (17%), and was left unknown in 15 (28.3%) cases. Among the 64 early neonatal deaths, prematurity was attributed as the cause of death in 32 (50%) cases, birth asphyxia, and infections each in 11 (17.2%). CONCLUSIONS: The perinatal mortality surveillance system identified the causes of death in most of the cases in our observation. Prematurity was identified as the commonest cause of early neonatal deaths and preterm labor was the commonest cause responsible for perinatal deaths overall. The perinatal deaths should be investigated to establish exact causes of deaths which can be useful to develop prevention strategies.


Subject(s)
Perinatal Death , Cause of Death , Cross-Sectional Studies , Female , Humans , Infant, Newborn , Male , Nepal/epidemiology , Perinatal Death/etiology , Perinatal Mortality , Pregnancy , Tertiary Care Centers
9.
J Forensic Leg Med ; 86: 102304, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35032861

ABSTRACT

The practice of autopsy for medico-legal purposes in Nepal was started during the 1960s when jail doctors used to perform the autopsy. However, the medico-legal service in clinical forensic settings is less than three decades old. In Nepal, a police inquest is done for all the unnatural deaths who then subjects the body for medico-legal autopsy at the nearest government hospital. Except for a few hospitals where forensic medicine experts are available, the medico-legal work in Nepal is done by medical officers most of who have no forensic qualification. For a country with a population of nearly 30 million, there are less than 50 forensic medicine experts who are currently practicing. There are 21 medical colleges in Nepal each having a forensic medicine department engaged in teaching forensic medicine as a separate subject in the undergraduate medical curriculum. Currently, postgraduate courses are also offered in the country. However, there is a lack of uniformity in the curriculum set by different universities for both postgraduate and undergraduate education. Due to the lack of forensic medicine faculty members in some medical colleges, the undergraduate students of medicine have to undertake the exam being taught by some guest lectures and without witnessing a single medico-legal autopsy. To standardize the medico-legal services and forensic medicine education, the Medico-Legal Society of Nepal was established with an aim to conduct regular seminars, conferences, and CMEs and also various training programs for the non-forensic medicine experts who deal with medico-legal cases. This paper aims to provide a brief history of medico-legal practice in Nepal, the current situation, and future plans to improve the medico-legal service of the country.


Subject(s)
Forensic Medicine , Physicians , Autopsy , Curriculum , Forensic Medicine/education , Humans , Nepal
10.
Clin Infect Dis ; 73(Suppl_5): S396-S400, 2021 12 15.
Article in English | MEDLINE | ID: mdl-34910170

ABSTRACT

BACKGROUND: Minimally invasive tissue sampling (MITS) is a useful tool to determine cause of death in low- and middle-income countries (LMICs). In 2019 the MITS Surveillance Alliance supported the implementation of small-scale postmortem studies using MITS in several LMICs. METHODS: In this article we describe the preparations, challenges, and lessons learned as part of implementing MITS across 4 study sites in 3 countries: Nepal, Rwanda, and Tanzania. We describe the process for building capacity to conduct MITS, which consisted of training in MITS sample collection, individual site assessment to determine readiness and gaps prior to implementation, site visits as sites began implementation of MITS, and feedback based on remote evaluation of histology slides via an online portal. RESULTS: The 4 study sites each conducted 100 MITS, for a total of 400. All 4 sites lacked sufficient infrastructure and facilities to conduct MITS, and upgrades were required. Common challenges faced by sites included that clinical autopsies were neither routinely conducted nor widely accepted. Limited clinical records made cause of death determination more difficult. Lessons learned included the importance of sensitization of the community and medical staff to MITS to enhance understanding and increase consent. CONCLUSIONS: The study sites accomplished MITS and utilized the available support systems to overcome the challenges. The quality of the procedures was satisfactory and was facilitated through the organized capacity-building programs.


Subject(s)
Capacity Building , Hospitals , Cause of Death , Humans , Nepal , Rwanda , Tanzania
11.
Clin Infect Dis ; 73(Suppl_5): S401-S407, 2021 12 15.
Article in English | MEDLINE | ID: mdl-34910172

ABSTRACT

BACKGROUND: Low- and middle-income countries (LMICs) face disproportionately high mortality rates, yet the causes of death in LMICs are not robustly understood, limiting the effectiveness of interventions to reduce mortality. Minimally invasive tissue sampling (MITS) is a standardized postmortem examination method that holds promise for use in LMICs, where other approaches for determining cause of death are too costly or unacceptable. This study documents the costs associated with implementing the MITS procedure in LMICs from the healthcare provider perspective and aims to inform resource allocation decisions by public health decisionmakers. METHODS: We surveyed 4 sites in LMICs across Sub-Saharan Africa and South Asia with experience conducting MITS. Using a bottom-up costing approach, we collected direct costs of resources (labor and materials) to conduct MITS and the pre-implementation costs required to initiate MITS. RESULTS: Initial investments range widely yet represent a substantial cost to implement MITS and are determined by the existing infrastructure and needs of a site. The costs to conduct a single case range between $609 and $1028 per case and are driven by labor, sample testing, and MITS supplies costs. CONCLUSIONS: Variation in each site's use of staff roles and testing protocols suggests sites conducting MITS may adapt use of resources based on available expertise, equipment, and surveillance objectives. This study is a first step toward necessary examinations of cost-effectiveness, which may provide insight into cost optimization and economic justification for the expansion of MITS.


Subject(s)
Developing Countries , Income , Autopsy/methods , Cause of Death , Humans , Poverty
12.
Clin Infect Dis ; 73(Suppl_5): S415-S421, 2021 12 15.
Article in English | MEDLINE | ID: mdl-34910184

ABSTRACT

BACKGROUND: Bacterial diseases are the leading cause of mortality globally, and due to haphazard use of antibiotics, antimicrobial resistance has become an emerging threat. METHODS: This cross-sectional observational study utilized a minimally invasive tissue sampling procedure to determine the cause of death among an adult population. Bacterial cultures (blood, cerebrospinal fluid, lung tissue) and antibiotic susceptibility were evaluated, and the results were compared between community and hospital deaths. RESULTS: Of 100 deceased persons studied, 76 (76%) deaths occurred in the community and 24 (24%) in the hospital. At least 1 bacterial agent was cultured from 86 (86%) cases; of these, 74 (86%) had a bacterial disease attributed as the primary cause of death, with pneumonia (35, 47.3%), sepsis (33, 44.6%), and meningitis (3, 4.1%) most common. Of 154 bacterial isolates (76.6% from the community and 23.4% from the hospital) detected from 86 culture-positive cases, 26 (16.8%) were multidrug-resistant (MDR). Klebsiella species were the most common (13 of 26) MDR organisms. The odds of getting an MDR Klebsiella infection was 6-fold higher among hospital deaths compared with community deaths (95% confidence interval [CI], 1.37-26.40; P = .017) and almost 23-fold higher (CI, 2.45-213.54; P = .006) among cases with prior antibiotic use compared to those without. CONCLUSIONS: High incidence of serious bacterial infections causing death of adults in the community, with most MDR organisms isolated from hospitalized cases, calls for robust surveillance mechanisms and infection prevention activities at the community level and evidence-driven antibiotic stewardship in healthcare settings.


Subject(s)
Bacterial Infections , Drug Resistance, Multiple, Bacterial , Adult , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Bacterial Infections/drug therapy , Bacterial Infections/epidemiology , Cross-Sectional Studies , Hospitals , Humans , Microbial Sensitivity Tests , Nepal/epidemiology
13.
Int J Surg Case Rep ; 89: 106591, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34798551

ABSTRACT

INTRODUCTION: Air bag deployment after high velocity trauma has been associated with burn injuries. So, we aimed to present a clinical case report associated with air bag deployment experienced by the author himself. CASE PRESENTATION: The author was driving a hatchback car which collided head on with the high speeding vehicle from opposite direction. He sustained a burn injury around 4 × 3 cm in size in the flexor aspect of right forearm involving epidermis and some part of dermis which was superficial partial thickness in nature when the air bag deployment was observed at both the sides. Burn injury was healed with topical antibiotics and regular dressings with no any complications. DISCUSSION: Air bag deployment has always been a safety measures for the road traffic injuries but the safety comes with a cost. It has been associated with burn injuries, especially chemical induced, thermal and frictional burns. Timely diagnosis of type of burn and intervention is required in order to minimize complications associated with burns. CONCLUSION: Though burn injuries associated with air bag deployment cause less harm or complications, the companies making such commodities should explore the further options in order to develop burn injury free vehicle safety.

14.
J Nepal Health Res Counc ; 19(2): 384-389, 2021 Sep 06.
Article in English | MEDLINE | ID: mdl-34601535

ABSTRACT

BACKGROUND: Problem based learning is self-directed form of learning. Problem of Diabetes Mellitus was chosen. The objective was to evaluate perception of students towards Problem based learning and test their understanding. METHODS: A descriptive study was conducted from November 2019 till October 2020. An online Problem based learning session of a week was conducted to second-year Bachelors of Dental Surgery students using online applications. Tutors facilitated students in a group of five to six each. Pre-post testing of evaluation questions was done. At end of session, feedback of students on Problem based learning and tutor of Problem based learning were received with 'Dolmans and Schmidt' and 'Dolmans and Ginns' questionnaire. RESULTS: There was increase in correct response in nine out of 12 evaluation questions. Most students agreed to influence of discussion, content tested, course objectives, lectures, tutor and reference literature. The students agreed that tutors facilitated active, self-directed, contextual and collaborative learning. CONCLUSIONS: The influence of discussion among participants, content tested, course objectives, reference literature during the Problem based learning session were agreed upon by majority of the students. The tutors' role was accepted by participants in terms of stimulation to self-directed, active, collaborative and contextual learning.


Subject(s)
Education, Medical, Undergraduate , Students, Medical , Humans , Nepal , Perception , Problem-Based Learning , Research , Students, Dental
15.
Risk Manag Healthc Policy ; 14: 2253-2261, 2021.
Article in English | MEDLINE | ID: mdl-34104016

ABSTRACT

PURPOSE: The study was conducted to explore the perception of healthcare workers and staff towards the risk of COVID-19 vaccination and to study vaccine hesitancy amongst them. METHODS: A total of 266 healthcare workers working in a medical college in Nepal were studied using a questionnaire consisting of three sections: demographics, experiences and perception of COVID-19, and COVID-19 vaccine safety. Data were analyzed using IBM SPSS version 26. The total perception score was calculated by noting respondent's agreement with a set of eleven statements using a Likert-type scale. Non-parametric tests (Mann-Whitney U and Kruskal-Wallis) were used for analysis (p<0.05). RESULTS: Altogether, 13.9% of respondents had been diagnosed COVID-19 positive prior to the survey. Many considered themselves to be at increased risk of contracting COVID-19. Only over one third (38.3%) were willing to be vaccinated. The most common reason for refusal/hesitancy was concern about vaccine safety. The median (interquartile range) total perception score was 36 (4) (maximum possible score=55). The score was significantly higher among those who had been diagnosed COVID positive, those who perceived the pandemic as being moderate or severe and among those willing to be vaccinated. CONCLUSION: Addressing doubts related to vaccine safety and providing more data on the safety of vaccine may be helpful in overcoming hesitancy.

16.
J Nepal Health Res Counc ; 19(1): 101-106, 2021 Apr 23.
Article in English | MEDLINE | ID: mdl-33934142

ABSTRACT

BACKGROUND: The average stage of attrition in permanent first and second molars is an established method of age estimation in the adult population. The study was conducted with an objective of age estimation from the average stage of attrition of permanent molars. METHODS: A total of 451 individuals of age more than 20 years were examined. Nepalese individuals with intact first and second permanent molars in the maxillary and mandibular arch on either side were included. The average stage of attrition of the maxillary first and second permanent molars on either side was calculated and subjected to regression analysis to derive equations. RESULTS: Among a total of 451 participants, 231 (51.22%) were females and 220 (48.78%) males, with a mean age of 44.3 ± 13.9 years. There was a strong correlation between age and average stage of attrition of molars. The correlation was stronger for upper molars compared to the lowers. Additionally, the mean of the difference between real age and estimated age was lower for maxillary compared to mandibular molars. Compared to age estimation by univariable regression, multivariable regression had greater accuracy. Similarly, estimation of age from maxillary molars was more accurate as compared to mandibular (difference in years: 3.82 ± 3.03 for maxillary molars and 5.17 ± 4.2 for mandibular molars). CONCLUSIONS: Maxillary teeth are better for age estimation and using both maxillary first and second permanent molars gives better accuracy.


Subject(s)
Goals , Molar , Adult , Female , Humans , Male , Middle Aged , Nepal , Young Adult
17.
Clin Case Rep ; 9(3): 1667-1671, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33768911

ABSTRACT

Minimal invasive tissue sampling (MITS) technique detected HIV infection and disseminated cryptococcosis in an adult female with sudden death. A proper autopsy is essential to diagnose the exact cause of death and MITS can suffice in natural deaths.

18.
J Nepal Health Res Counc ; 18(4): 686-691, 2021 Jan 21.
Article in English | MEDLINE | ID: mdl-33510511

ABSTRACT

BACKGROUND: Demirjian's method is widely used method for dental age estimation. This study was conducted with objectives of applying Demirjian's 8 teeth method to estimate age in Nepalese Population and to determine Nepal-specific formulas. METHODS: We had used the Orthopantomographs of Nepalese people of age above five and below 23 years. The radiographs were compared to the 'Tooth Development Chart' and each tooth studied was assigned with any one of the 10 developmental stages using Demirijian's 8 teeth method and total maturity scores determined. Formulas were derived using regression analysis, wherein the total maturity score obtained for each individual was considered as the independent variable and the corresponding age as the dependent variable in the STATA 15.1 statistical program. RESULTS: There was underestimation of age in both the sexes by the original method. Regression equations were derived for males and females separately for age five to 18 years and again after adding cases up to 23 years. The estimation was better for males up to 18 years [R2=0.94, Mean Absolute Error (MAE) 0.747 years and SD 0.644] than for females up to 18 years (R2 = 0.89, MAE 0.886 years and SD 0.925). The estimation was better for up to 18 years than for up to 23 years in both sexes. CONCLUSIONS: Demirijian's 8 teeth method underestimated age in the study population and thus population specific equations based on the method are better for dental age estimation. The age estimation utilizing the equations from Nepalese population has given acceptable results.


Subject(s)
Age Determination by Teeth , Tooth , Adolescent , Adult , Child , Child, Preschool , Female , Forensic Dentistry , Humans , Male , Nepal , Radiography, Panoramic , Tooth/diagnostic imaging , Young Adult
19.
JNMA J Nepal Med Assoc ; 59(244): 1293-1296, 2021 Dec 11.
Article in English | MEDLINE | ID: mdl-35199792

ABSTRACT

INTRODUCTION: The outbreak of COVID-19  as changed patterns of mortality in different setups. The rate of suicide has increased in some countries during the pandemic while the overall death rates  have decreased. The study was conducted with objective to find out the prevalence of unnatural deaths among the autopsy cases brought at tertiary care hospital during COVID-19 pandemic period. METHODS: This is a descriptive cross-sectional study using the records of the medico legal autopsies conducted from 24th March 2020 to 23rd August 2020 during the COVID-19 pandemic in Pokhara Academy of Health Sciences. Ethical approval was taken from Institutional Review Committee of Pokhara Academy of Health Sciences (Reference number 28.2077/78). Whole sampling method was used. Records which were available were included in the study whereas those cases whose complete records were not available were excluded. Point estimate at 95% confidence interval was calculated along with frequency and proportion for binary data. RESULTS: Out of 188 deaths studied at the autopsy during the COVID-19 pandemic period, the prevalence of unnatural deaths was 147 (78.19%) (71.04-85.33 at 95% Confidence Interval). Among these deaths, 109 (74.14%) were males and 38 (25.85%) were females. Suicide was the most common manner attributing to 78 (53.06%) of the unnatural deaths. CONCLUSIONS: The prevalence of suicide was more than those demonstrated by earlier observations in similar settings before the pandemic period. Suicidal deaths were more common during the COVID 19 pandemic. This is an indicator of frustration of the people and necessary steps have to be taken to decrease such deaths in similar conditions to come.


Subject(s)
COVID-19 , Autopsy , Cross-Sectional Studies , Female , Humans , Male , Nepal/epidemiology , Pandemics , SARS-CoV-2 , Tertiary Care Centers
20.
JNMA J Nepal Med Assoc ; 56(212): 735-739, 2018.
Article in English | MEDLINE | ID: mdl-30387459

ABSTRACT

INTRODUCTION: The medico legal reports and certificates prepared by doctors can be used as valuable documentary evidence in the court of law. The study was designed with objectives to explore the perception of judges and lawyers about the quality of medico legal reports prepared by the doctors and their competence in providing the expert evidence in the court. METHODS: It is a questionnaire based cross sectional study conducted among the district judges and government attorneys of 75 districts of Nepal from March to May 2016. The data obtained was analysed by SPSS version 16.0. RESULTS: Among a total of 78 participants who responded the questionnaire, 40 (51.3%) were district judges and 38 (48.7%) district attorneys. Most of them graded that the reports prepared by the doctors were just average. Among them, 49 (63.6%) strongly agreed and 28 (36.4%) partially agreed that the reports were useful in deciding the cases. A total of 44 (56.4%) respondents strongly agreed and 34 (43.6%) partially agreed that expert opinion of the doctors in the courts were useful to decide the cases. Seventy one (92.2%) of them rated general doctors as moderately competent. CONCLUSIONS: The medical reports prepared by the Nepalese doctors were just average as perceived by judges and lawyers and the competency in presenting the evidence in courts was moderate as rated by them.


Subject(s)
Attitude to Health , Documentation , Expert Testimony , Jurisprudence , Lawyers/psychology , Cross-Sectional Studies , Documentation/standards , Female , Humans , Lawyers/statistics & numerical data , Male , Middle Aged , Nepal , Surveys and Questionnaires
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