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1.
Phys Rev Lett ; 127(22): 225001, 2021 Nov 24.
Article in English | MEDLINE | ID: mdl-34889640

ABSTRACT

We assess the magnetic field configuration in modern fusion devices by comparing experiments with the same heating power, between a stellarator and a heliotron. The key role of turbulence is evident in the optimized stellarator, while neoclassical processes largely determine the transport in the heliotron device. Gyrokinetic simulations elucidate the underlying mechanisms promoting stronger ion scale turbulence in the stellarator. Similar plasma performances in these experiments suggests that neoclassical and turbulent transport should both be optimized in next step reactor designs.

2.
Phys Rev Lett ; 107(5): 055001, 2011 Jul 29.
Article in English | MEDLINE | ID: mdl-21867074

ABSTRACT

Neoclassical toroidal viscosities (NTVs) in tokamaks are investigated using a δf Monte Carlo simulation, and are successfully verified with a combined analytic theory over a wide range of collisionality. A Monte Carlo simulation has been required in the study of NTV since the complexities in guiding-center orbits of particles and their collisions cannot be fully investigated by any means of analytic theories alone. Results yielded the details of the complex NTV dependency on particle precessions and collisions, which were predicted roughly in a combined analytic theory. Both numerical and analytic methods can be utilized and extended based on these successful verifications.

3.
Phys Rev Lett ; 107(24): 245002, 2011 Dec 09.
Article in English | MEDLINE | ID: mdl-22243005

ABSTRACT

The relation between magnetic geometry and the level of ion-temperature-gradient (ITG) driven turbulence in stellarators is explored through gyrokinetic theory and direct linear and nonlinear simulations. It is found that the ITG radial heat flux is sensitive to details of the magnetic configuration that can be understood in terms of the linear behavior of zonal flows. The results throw light on the question of how the optimization of neoclassical confinement is related to the reduction of turbulence.

4.
Phys Rev Lett ; 100(19): 195002, 2008 May 16.
Article in English | MEDLINE | ID: mdl-18518454

ABSTRACT

Gyrokinetic Vlasov simulations of the ion temperature gradient turbulence are performed in order to investigate effects of helical magnetic configurations on turbulent transport and zonal flows. The obtained results confirm the theoretical prediction that helical configurations optimized for reducing neoclassical ripple transport can simultaneously reduce the turbulent transport with enhancing zonal-flow generation. Stationary zonal-flow structures accompanied with transport reduction are clearly identified by the simulation for the neoclassically optimized helical geometry. The generation of the stationary zonal flow explains a physical mechanism for causing the confinement improvement observed in the inward-shifted plasma in the Large Helical Device [O. Motojima, Nucl. Fusion 43, 1674 (2003)].

5.
Insect Mol Biol ; 15(6): 773-83, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17201770

ABSTRACT

Ligand-gated chloride channels (LGICs) are important targets for insecticides and parasiticides. Genes encoding subunits of two LGICs, a glutamate-gated chloride channel (MdGluCl-alpha) and a gamma-aminobutyric acid (GABA)-gated chloride channel (MdRdl), were cloned from house-flies (Musca domestica L.). These genes were first expressed independently in Xenopus laevis oocytes by cRNA injection in order to investigate the pharmacology of these ligand-gated channels using two-electrode voltage-clamp electrophysiology. It was found that L-glutamate and GABA activated the MdGluCl-alpha homo-oligomers with an EC(50) value of 30 microM and the MdRdl homo-oligomers with an EC(50) value of 101 microM, respectively. Both channels were chloride ion-permeable, and the MdRdl channel was more sensitive to chloride channel blockers, such as gamma-hexachlorocyclohexane (gamma-HCH), fipronil and picrotoxinin, than the MdGluCl-alpha channel. MdGluCl-alpha required only 1-2 days of incubation after cRNA injection to be expressed in oocytes, whereas 4-7 days of incubation was necessary to achieve MdRdl expression. However, when the cRNA of MdGluCl-alpha was injected at a dose of 1% (w/w) 1 day after the injection of the cRNA of MdRdl, a significant increase in the current amplitude of responses to GABA was observed, and the incubation period necessary for MdRdl expression became shorter. These results suggest that MdGluCl-alpha assists in the expression of MdRdl when the two are coexpressed.


Subject(s)
Chloride Channels/metabolism , Gene Expression , Ion Channel Gating , Muscidae/metabolism , Oocytes/metabolism , Xenopus laevis , gamma-Aminobutyric Acid/metabolism , Animals , Antiparasitic Agents/pharmacology , Chloride Channel Agonists , Chloride Channels/antagonists & inhibitors , Chloride Channels/chemistry , Cloning, Molecular , DNA, Complementary/metabolism , Dose-Response Relationship, Drug , GABA Agonists/pharmacology , GABA Antagonists/pharmacology , Glutamates/pharmacology , Hexachlorocyclohexane/pharmacology , Ion Channel Gating/drug effects , Oocytes/drug effects , Picrotoxin/analogs & derivatives , Picrotoxin/pharmacology , Protein Structure, Quaternary/drug effects , Pyrazoles/pharmacology , RNA, Complementary/metabolism , Sesterterpenes , gamma-Aminobutyric Acid/pharmacology
6.
Phys Rev Lett ; 94(11): 115001, 2005 Mar 25.
Article in English | MEDLINE | ID: mdl-15903865

ABSTRACT

A theory for describing collisionless long-time behavior of zonal flows in helical systems is presented and its validity is verified by gyrokinetic-Vlasov simulation. It is shown that, under the influence of particles trapped in helical ripples, the response of zonal flows to a given source becomes weaker for lower radial wave numbers and deeper helical ripples while a high-level zonal-flow response, which is not affected by helical-ripple-trapped particles, can be maintained for a longer time by reducing their bounce-averaged radial drift velocity. This implies a possibility that helical configurations optimized for reducing neoclassical ripple transport can simultaneously enhance zonal flows which lower anomalous transport.

7.
Phys Rev E Stat Nonlin Soft Matter Phys ; 66(6 Pt 2): 066408, 2002 Dec.
Article in English | MEDLINE | ID: mdl-12513413

ABSTRACT

The structural properties of an economical model for a confined plasma turbulence governor are investigated through bifurcation and stability analyses. A close relationship is demonstrated between the underlying bifurcation framework of the model and typical behavior associated with low- to high-confinement transitions such as shear-flow stabilization of turbulence and oscillatory collective action. In particular, the analysis evinces two types of discontinuous transition that are qualitatively distinct. One involves classical hysteresis, governed by viscous dissipation. The other is intrinsically oscillatory and nonhysteretic, and thus provides a model for the so-called dithering transitions that are frequently observed. This metamorphosis, or transformation, of the system dynamics is an important late side-effect of symmetry breaking, which manifests as an unusual nonsymmetric transcritical bifurcation induced by a significant shear-flow drive.

8.
Biosci Biotechnol Biochem ; 63(1): 232-4, 1999 Jan.
Article in English | MEDLINE | ID: mdl-10052150

ABSTRACT

Antibodies were raised against a synthetic antigen carrying the N-terminus peptide of ALMB-toxin, which had been isolated from the antlion, Myrmeleon bore, that exhibited high specificity to the toxin. Analyses with the antibodies showed the toxin to be present mainly at the larval stage and localized in a region from the thorax to abdomen of the larval body.


Subject(s)
Insecta/immunology , Toxins, Biological/immunology , Amino Acid Sequence , Animals , Antibodies , Antigens/genetics , Insecta/genetics , Larva/immunology , Mice , Molecular Sequence Data , Peptides/genetics , Peptides/immunology , Toxins, Biological/genetics
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