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1.
Abdom Radiol (NY) ; 2024 Jul 09.
Article in English | MEDLINE | ID: mdl-38980403

ABSTRACT

OBJECTIVES: To compare the image quality of 1.5T and 3T prostate MRIs of the same post-hip arthroplasty patients, with a specific focus on the degree of susceptibility artifacts. METHODS: This single-center retrospective study included post-hip arthroplasty patients who underwent 1.5T prostate MRIs between 2021 and 2023, as well as comparative 3T prostate MRIs. Three blinded abdominal radiologists retrospectively reviewed their diffusion-weighted imaging (DWI, 50 s/mm2), T2-weighted imaging (T2WI), and dynamic contrast-enhanced imaging (DCE) to evaluate the image quality. The degree of susceptibility artifacts was categorized using a three-point scale, with 3 indicating the least artifact and 1 indicating the most. Image quality was also evaluated using Prostate Imaging Quality (PI-QUAL) version 2. The median of the three raters' scores was compared between 1.5T and 3T prostate MRIs using the Wilcoxon signed-rank test. The inter-rater agreement was evaluated using the multi-rater generalized kappa. RESULTS: Twenty pairs of 1.5T and 3T prostate MRI examinations from 20 unique patients were included. The DWI susceptibility artifact score at 1.5T was significantly higher than at 3T (mean score ± standard deviation, 2.80 ± 0.41 vs. 2.35 ± 0.93, p = 0.014). In contrast, no significant differences were observed in the susceptibility artifact scores in T2WI and DCE, or in the PI-QUAL score. The inter-reader agreement in the susceptibility artifact score was moderate (multi-rater generalized kappa: 0.60) in DWI, perfect in T2WI (not applicable), and substantial (0.65) in DCE. The inter-reader agreement was fair (0.27) in the PI-QUAL score. CONCLUSION: Using 1.5T scanners may be preferable to reduce susceptibility artifacts from hip prostheses in DWI.

2.
J Radiol Case Rep ; 18(1): 1-7, 2024.
Article in English | MEDLINE | ID: mdl-38910588

ABSTRACT

This case report discusses a diagnosis of uterine torsion in an 84-year-old woman who presented with five days of right lower quadrant abdominal pain, nausea, vomiting, constipation, and poor intake. Computed tomography (CT) imaging demonstrated a whorled configuration at the junction of the cervix and lower uterine segment, with the left gonadal vein crossing midline, and two previously known right leiomyomas now appearing on the left. These findings were consistent with the diagnosis of uterine torsion. She then underwent an urgent exploratory laparotomy, and the uterus was found to be dextroverted 270 degrees, with dark mottled purple tissue and engorged vessels. A supracervical hysterectomy and bilateral salpingo-oopherectomy were performed. Final pathology demonstrated extensive necrosis. This case reviews the classic presentation and imaging findings for the rare diagnosis of uterine torsion and options for management of both non-gravid and gravid patients.


Subject(s)
Leiomyoma , Postmenopause , Tomography, X-Ray Computed , Torsion Abnormality , Uterine Neoplasms , Humans , Female , Leiomyoma/surgery , Leiomyoma/diagnostic imaging , Leiomyoma/complications , Leiomyoma/pathology , Aged, 80 and over , Torsion Abnormality/diagnostic imaging , Torsion Abnormality/surgery , Uterine Neoplasms/diagnostic imaging , Uterine Neoplasms/surgery , Uterine Neoplasms/complications , Uterine Neoplasms/pathology , Uterine Diseases/diagnostic imaging , Uterine Diseases/surgery , Uterine Diseases/pathology , Hysterectomy , Diagnosis, Differential
3.
Br J Radiol ; 97(1160): 1431-1436, 2024 Aug 01.
Article in English | MEDLINE | ID: mdl-38830085

ABSTRACT

OBJECTIVE: Characterize the CT findings of abdominopelvic Castleman disease, including a new observation involving the perinodal fat. METHODS: Multi-centre search at 5 institutions yielded 76 adults (mean age, 42.1 ± 14.3 years; 38 women/38 men) meeting inclusion criteria of histopathologically proven Castleman disease with nodal involvement at abdominopelvic CT. Retrospective review of the dominant nodal mass was assessed for size, attenuation, and presence of calcification, and for prominence and soft-tissue infiltration of the perinodal fat. Hypervascular nodal enhancement was based on both subjective and objective comparison with aortic blood pool attenuation. RESULTS: Abdominal involvement was unicentric in 48.7% (37/76) and multicentric in 51.3% (39/76), including 31 cases with extra-abdominal involvement. Histopathologic subtypes included hyaline vascular variant (HVV), plasma cell variant (PCV), mixed HVV/PCV, and HHV-8 variant in 39, 25, 3 and 9 cases, respectively. The dominant nodal mass measured 4.4 ± 1.9 cm and 3.2 ± 1.7 cm in mean long- and short-axis, respectively, and appeared hypervascular in 58.6% (41/70 with IV contrast). Internal calcification was seen in 22.4% (17/76). Infiltration of the perinodal fat, with or without hypertrophy, was present in 56.6% (43/76), more frequent with hypervascular vs non-hypervascular nodal masses (80.5% vs 20.7%; P < .001). Among HVV cases, 76.9% were unicentric, 71.1% appeared hypervascular, and 69.2% demonstrated perinodal fat infiltration. CONCLUSION: Hypervascular nodal masses demonstrating prominence and infiltration of perinodal fat at CT can suggest the specific diagnosis of Castleman disease, especially the HVV. ADVANCES IN KNOWLEDGE: Abdominopelvic nodal masses that demonstrate hypervascular enhancement and prominent infiltration of the perinodal fat at CT can suggest the diagnosis of Castleman disease, but nonetheless requires tissue sampling.


Subject(s)
Castleman Disease , Tomography, X-Ray Computed , Humans , Castleman Disease/diagnostic imaging , Castleman Disease/pathology , Female , Adult , Male , Retrospective Studies , Tomography, X-Ray Computed/methods , Middle Aged , Lymph Nodes/diagnostic imaging , Lymph Nodes/pathology , Radiography, Abdominal/methods , Pelvis/diagnostic imaging , Aged
6.
Semin Ultrasound CT MR ; 45(2): 139-151, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38373671

ABSTRACT

The field of Radiology is continually changing, requiring corresponding evolution in both medical student and resident training to adequately prepare the next generation of radiologists. With advancements in adult education theory and a deeper understanding of perception in imaging interpretation, expert educators are reshaping the training landscape by introducing innovative teaching methods to align with increased workload demands and emerging technologies. These include the use of peer and interdisciplinary teaching, gamification, case repositories, flipped-classroom models, social media, and drawing and comics. This publication aims to investigate these novel approaches and offer persuasive evidence supporting their incorporation into the updated Radiology curriculum.


Subject(s)
Curriculum , Radiologists , Radiology , Humans , Radiologists/education , Radiology/education
7.
Radiographics ; 43(6): e220146, 2023 06.
Article in English | MEDLINE | ID: mdl-37200220

ABSTRACT

Amniotic fluid (AF) is an integral part of the fetal environment and is essential for fetal growth and development. Pathways of AF recirculation include the fetal lungs, swallowing, absorption through the fetal gastrointestinal tract, excretion through fetal urine production, and movement. In addition to being a marker for fetal health, adequate AF is necessary for fetal lung development, growth, and movement. The role of diagnostic imaging is to provide a detailed fetal survey, placental evaluation, and clinical correlation with maternal conditions to help identify causes of AF abnormalities and thereby enable specific therapy. Oligohydramnios prompts evaluation for fetal growth restriction as well as genitourinary issues, including renal agenesis, multicystic dysplastic kidneys, ureteropelvic junction obstruction, and bladder outlet obstruction. Premature preterm rupture of membranes should also be clinically excluded as a cause of oligohydramnios. Clinical trials evaluating amnioinfusion are underway as a potential intervention for renal causes of oligohydramnios. Most cases of polyhydramnios are idiopathic, with maternal diabetes being a common cause. Polyhydramnios prompts evaluation for fetal gastrointestinal obstruction and oropharyngeal or thoracic masses, as well as neurologic or musculoskeletal anomalies. Amnioreduction is performed only for maternal indications such as symptomatic polyhydramnios causing maternal respiratory distress. Polyhydramnios with fetal growth restriction is paradoxical and can occur with maternal diabetes and hypertension. When these maternal conditions are absent, this raises concern for aneuploidy. The authors describe the pathways of AF production and circulation, US and MRI assessment of AF, disease-specific disruption of AF pathways, and an algorithmic approach to AF abnormalities. ©RSNA, 2023 Online supplemental material is available for this article. Quiz questions for this article are available through the Online Learning Center.


Subject(s)
Diabetes Mellitus , Oligohydramnios , Polyhydramnios , Infant, Newborn , Female , Pregnancy , Humans , Amniotic Fluid/diagnostic imaging , Amniotic Fluid/metabolism , Oligohydramnios/diagnostic imaging , Polyhydramnios/diagnosis , Polyhydramnios/metabolism , Fetal Growth Retardation , Placenta , Diabetes Mellitus/metabolism
8.
Diagnostics (Basel) ; 12(9)2022 Sep 05.
Article in English | MEDLINE | ID: mdl-36140556

ABSTRACT

Purpose: To assess the influence of different dual-energy CT (DECT) scanner techniques on the severity of visceral-motion-related artifacts on the liver. Methods: Two independent readers retrospectively evaluated visceral-motion-related artifacts on the liver on 120-kVp(-like), monoenergetic low- and high-keV, virtual non-contrast (VNC), and iodine images acquired on a dual-source, twin-beam, fast kV-switching, and dual-layer spectral detector scanner. Quantitative assessment: Depth of artifact extension into the liver, measurements of Hounsfield Units (HU) and iodine concentrations. Qualitative assessment: Five-point Likert scale (1 = none to 5 = severe). Artifact severity between image reconstructions were compared by Wilcoxon signed-rank and paired t-tests. Results: 615 contrast-enhanced routine clinical DECT scans of the abdomen were evaluated in 458 consecutive patients (mean age: 61 ± 14 years, 331 men). For dual-source and twin-beam scanners, depth of extension of artifacts into the liver was significantly shorter and artifact severity scores significantly lower for 120-kVp-like images compared with the other image reconstructions (p < 0.001, each). For fast kV-switching and spectral detector scanner images, depth of extension of artifacts was significantly shorter and artifact severity scores significantly lower for iodine images (p < 0.001, each). Dual-source 120-kVp-like and spectral detector iodine images reduced artifacts to an extent that no significant difference in HU or iodine concentrations between artifacts (dual-source: 97 HU, spectral detector: 1.9 mg/mL) and unaffected liver parenchyma (dual-source: 108 HU, spectral detector: 2.1 mg/mL) was measurable (dual-source: p = 0.32, spectral detector: p = 0.15). Conclusion: Visceral-motion-related artifacts on the liver can be markedly reduced by viewing 120-kVp-like images for dual-source and twin-beam DECT scanners and iodine images for fast kV-switching and dual-layer spectral detector DECT scanners.

9.
Radiographics ; 42(5): 1377-1397, 2022.
Article in English | MEDLINE | ID: mdl-35930473

ABSTRACT

Although eating disorders are common, they tend to be underdiagnosed and undertreated because social stigma tends to make patients less likely to seek medical attention and less compliant with medical treatment. Diagnosis is crucial because these disorders can affect any organ system and are associated with the highest mortality rate of any psychiatric disorder. Because of this, imaging findings, when recognized, can be vital to the diagnosis and management of eating disorders and their related complications. The authors familiarize the radiologist with the pathophysiology and sequelae of eating disorders and provide an overview of the related imaging findings. Some imaging findings associated with eating disorders are nonspecific, and others are subtle. The presence of these findings should alert the radiologist to correlate them with the patient's medical history and laboratory results and the clinical team's findings at the physical examination. The combination of these findings may suggest a diagnosis that might otherwise be missed. Topics addressed include (a) the pathophysiology of eating disorders, (b) the clinical presentation of patients with eating disorders and their medical complications and sequelae, (c) the imaging features associated with common and uncommon sequelae of eating disorders, (d) an overview of management and treatment of eating disorders, and (e) conditions that can mimic eating disorders (eg, substance abuse, medically induced eating disorders, and malnourishment in patients with cancer). Online supplemental material is available for this article. ©RSNA, 2022.


Subject(s)
Feeding and Eating Disorders , Substance-Related Disorders , Diagnosis, Differential , Diagnostic Imaging , Disease Progression , Feeding and Eating Disorders/diagnostic imaging , Humans
10.
Diagnostics (Basel) ; 12(4)2022 Mar 23.
Article in English | MEDLINE | ID: mdl-35453830

ABSTRACT

Background: Peristalsis-related streak artifacts on the liver compromise image quality and diagnostic accuracy. Purpose: To assess dual-layer spectral-detector computed tomography (CT) image reconstructions for reducing intestinal peristalsis-related streak artifacts on the liver. Methods: We retrospectively evaluated 220 contrast-enhanced abdominal dual-energy CT scans in 131 consecutive patients (mean age: 68 ± 10 years, 120 men) who underwent routine clinical dual-layer spectral-detector CT imaging (120 kVp, 40 keV, 200 keV, virtual non-contrast (VNC), iodine images). Two independent readers evaluated bowel peristalsis streak artifacts on the liver qualitatively on a five-point Likert scale (1 = none to 5 = severe) and quantitatively by depth of streak artifact extension into the liver and measurements of Hounsfield Unit and iodine concentration differences from normal liver. Artifact severity between image reconstructions were compared by Wilcoxon signed-rank and paired t-tests. Results: 12 scans were excluded due to missing spectral data, artifacts on the liver originating from metallic foreign materials, or oral contrast material. Streak artifacts on the liver were seen in 51/208 (25%) scans and involved the left lobe only in 49/51 (96%), the right lobe only in 0/51 (0%), and both lobes in 2/51 (4%) scans. Artifact frequency was lower in iodine than in 120 kVp images (scans 18/208 vs. 51/208, p < 0.001). Artifact severity was less in iodine than in 120 kVp images (median score 1 vs. 3, p < 0.001). Streak artifact extension into the liver was shorter in iodine than 120 kVp images (mean length 2 ± 4 vs. 12 ± 5 mm, p < 0.001). Hounsfield Unit and iodine concentration differed significantly between bright streak artifacts and normal liver in 120 kVp, 40 keV, 200 keV, and VNC images (p < 0.001, each), but not in iodine images (p = 0.23). Conclusion: Intestinal peristalsis-related streak artifacts commonly affect the left liver lobe at CT and can be substantially reduced by viewing iodine dual-energy CT image reconstructions.

11.
AJR Am J Roentgenol ; 219(2): 233-243, 2022 08.
Article in English | MEDLINE | ID: mdl-35293233

ABSTRACT

BACKGROUND. Data are limited regarding utility of positive oral contrast material for peritoneal tumor detection on CT. OBJECTIVE. The purpose of this article is to compare positive versus neutral oral contrast material for detection of malignant deposits in nonsolid intraabdominal organs on CT. METHODS. This retrospective study included 265 patients (133 men, 132 women; median age, 61 years) who underwent an abdominopelvic CT examination in which the report did not suggest presence of malignant deposits and a subsequent CT examination within 6 months in which the report indicated at least one unequivocal malignant deposit. Examinations used positive (iohexol; n = 100) or neutral (water; n = 165) oral agents. A radiologist reviewed images to assess whether the deposits were visible (despite clinical reports indicating no deposits) on unblinded comparison with the follow-up examinations; identified deposits were assigned to one of seven intraabdominal compartments. The radiologist also assessed adequacy of bowel filling with oral contrast material. Two additional radiologists independently reviewed examinations in blinded fashion for malignant deposits. NPV was assessed of clinical CT reports and blinded retrospective readings for detection of malignant deposits visible on unblinded comparison with follow-up examinations. RESULTS. Unblinded review identified malignant deposits in 58.1% (154/265) of examinations. In per-patient analysis of clinical reports, NPV for malignant deposits was higher for examinations with adequate bowel filling with positive oral contrast material (65.8% [25/38]) than for examinations with inadequate bowel filling with positive oral contrast material (45.2% [28/62], p = .07) or with neutral oral contrast material regardless of bowel filling adequacy (35.2% [58/165], p = .002). In per-compartment analysis of blinded interpretations, NPV was higher for examinations with adequate and inadequate bowel filling with positive oral contrast material than for examinations with neutral oral contrast regardless of bowel filling adequacy (reader 1: 94.7% [234/247] and 92.5% [382/413] vs 88.3% [947/1072], both p = .045; reader 2: 93.1% [228/245] and 91.6% [361/394] vs 85.9% [939/1093], both p = .01). CONCLUSION. CT has suboptimal NPV for malignant deposits in intraabdominal nonsolid organs. Compared with neutral material, positive oral contrast material improves detection, particularly with adequate bowel filling. CLINICAL IMPACT. Optimization of bowel preparation for oncologic CT may help avoid potentially severe clinical consequences of missed malignant deposits.


Subject(s)
Contrast Media , Tomography, X-Ray Computed , Female , Humans , Intestines , Iohexol , Male , Middle Aged , Retrospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed/methods
12.
Emerg Radiol ; 29(3): 611-614, 2022 Jun.
Article in English | MEDLINE | ID: mdl-35128620

ABSTRACT

In this case report, dual-energy CT was critical in the diagnosis of acute mesenteric ischemia by differentiating normal contrast-enhanced bowel and hemorrhagic necrosis. Iodine map showed a segment of small bowel with minimal contrast enhancement, and virtual non-contrast imaging revealed hyperattenuating bowel. This finding changed management for the patient and prevented complications from impending bowel perforation. Histopathological analysis confirmed hemorrhagic necrosis of the bowel segment. In cases of suspected bowel ischemia, dual-energy CT can distinguish bowel wall hemorrhage from contrast enhancement and allow for accurate diagnosis.


Subject(s)
Iodine , Mesenteric Ischemia , Contrast Media , Gastrointestinal Hemorrhage , Humans , Intestine, Small , Ischemia , Mesenteric Ischemia/diagnostic imaging , Necrosis/complications , Necrosis/pathology , Tomography, X-Ray Computed/methods
13.
Curr Probl Diagn Radiol ; 51(3): 344-350, 2022.
Article in English | MEDLINE | ID: mdl-33678528

ABSTRACT

This review sets forth an approach to performing and interpreting shoulder ultrasound in patients with prior rotator cuff repair and presents a comprehensive review of normal expected findings, postsurgical complications and common artifacts encountered in clinical practice.


Subject(s)
Rotator Cuff Injuries , Shoulder Joint , Artifacts , Humans , Postoperative Complications/diagnostic imaging , Rotator Cuff/diagnostic imaging , Rotator Cuff/surgery , Rotator Cuff Injuries/diagnostic imaging , Rotator Cuff Injuries/surgery , Treatment Outcome , Ultrasonography
14.
Acad Radiol ; 29(2): 287-293, 2022 02.
Article in English | MEDLINE | ID: mdl-33341373

ABSTRACT

RATIONALE AND OBJECTIVES: To assess resident and fellowship program director (PD) perceptions of the abdominal radiology fellowship application process following the first cycle in which an embargo on interviews until December 1, 2019 was set according to the Society of Chairs of Academic Radiology Departments (SCARD) timeline for the 2021-2022 abdominal imaging fellowship year. MATERIALS AND METHODS: Eligible study participants included fellowship PDs of all abdominal imaging programs in the United States and residents that attended the Society of Abdominal Radiology (SAR) 2020 Annual Meeting. A questionnaire was developed by content and survey experts, pilot tested, and administered from May to June 2020. RESULTS: A total of 39% (36/92) of all PDs and 30% (46/152) of all individuals identified as residents with valid email addresses that attended the SAR 2020 Annual Meeting responded to the survey with an overall response rate of 34%. Only 42% of PDs and 33% of residents supported moving to a match, while 62% of PDs and 70% of residents thought that a match would limit the autonomy of applicants. While most PDs and residents also agreed that the first iteration of the SCARD timeline allowed residents to make a more informed choice, the majority of PDs were dissatisfied with their experience. Most PDs and residents additionally want applications to be accepted no earlier than July and/or August of the R3 year (initial SCARD guidelines did not restrict timing), interviews to begin on November 1st or earlier of the R3 year (compared to December 1st set in the first iteration of the guidelines), and a gap of 2-4 weeks between the date of first interviews and notification of first offers (initial SCARD guidelines did not restrict timing). Lastly, an overwhelming majority of PDs and residents agreed that SAR should enforce the abdominal imaging fellowship application process. CONCLUSION: Following the first cycle of abdominal imaging fellowship applications conducted according to the SCARD guidelines, a majority of trainees and PDs felt the changes were favorable and were opposed to a formal match. Specific suggestions for improvement were elicited from stakeholders and will be incorporated for the next cycle.


Subject(s)
Internship and Residency , Radiology , Fellowships and Scholarships , Follow-Up Studies , Humans , Policy , Radiology/education , Surveys and Questionnaires , United States
16.
Radiographics ; 41(6): 1857-1875, 2021 Oct.
Article in English | MEDLINE | ID: mdl-34597219

ABSTRACT

Müllerian duct anomalies (MDAs) have important implications for the reproductive health of female patients. In patients with both infertility and recurrent pregnancy loss, the incidence of MDAs is as high as 25%. Congenital uterine anomalies are often only part of a complex set of congenital anomalies involving the cervix, vagina, and urinary tract. Multiple classification systems for MDAs exist, each with different criteria that vary most for the diagnosis of septate uterus. Recognizing the features that guide clinical management is essential for interpretation. Identification of an MDA should prompt evaluation for associated urinary tract anomalies. In patients with infertility who seek to use assisted reproductive technologies such as intrauterine insemination, recognition of MDAs may have an affect on reproductive success, particularly in patients who have an incomplete and clinically occult septum that divides the cervix. Two-dimensional US is the first-line modality for evaluating the uterus and adnexa. Three-dimensional (3D) US or MRI may help to visualize the external uterine fundal contour and internal indentation of the endometrial cavity, which are two morphologic characteristics that are keys to the diagnosis of congenital uterine anomalies. Hysterosalpingo contrast-enhanced US may be performed in conjunction with 3D US to evaluate uterine morphologic characteristics, the endometrial cavity, and tubal patency in a single examination. MRI helps to characterize rudimentary uteri in patients with müllerian hypoplasia and allows assessment for ectopic ureters, abnormally positioned ovaries, or associated deep infiltrative endometriosis. Online supplemental material is available for this article. ©RSNA, 2021.


Subject(s)
Mullerian Ducts , Urogenital Abnormalities , Cervix Uteri/diagnostic imaging , Female , Fertility , Humans , Mullerian Ducts/diagnostic imaging , Pregnancy , Urogenital Abnormalities/diagnostic imaging , Uterus/diagnostic imaging
17.
Abdom Radiol (NY) ; 46(12): 5462-5465, 2021 12.
Article in English | MEDLINE | ID: mdl-34482413

ABSTRACT

The authors provide a commentary on the current status of the Abdominal Radiology Fellowship recruitment process, which is not presently governed by a formal Match. Abdominal Radiology is the largest radiology subspecialty fellowship that remains outside of the Match. The Society of Abdominal Radiology convened a task force in 2019 to assess stakeholder viewpoints on a Match and found that the community was divided. Radiology departments and Abdominal Radiology fellowship program directors have voluntarily complied with a series of guidelines laid out by the Society of Chairs in Academic Radiology Departments during the two most recent recruiting cycles, but challenges in the process persist. Stakeholders report improved organization and fairness as a result of these procedural changes, and the authors suggest that Abdominal Radiology may continue to consider a formal fellowship Match in coming years.


Subject(s)
Internship and Residency , Radiology , Fellowships and Scholarships , Humans , Personnel Selection , Radiology/education , Surveys and Questionnaires , United States
18.
Radiographics ; 41(5): 1454-1474, 2021.
Article in English | MEDLINE | ID: mdl-34357805

ABSTRACT

Amyloidosis is a group of conditions defined by extracellular deposition of insoluble proteins that can lead to multiorgan dysfunction and failure. The systemic form of the disease is often associated with a plasma cell dyscrasia but may also occur in the setting of chronic inflammation, long-term dialysis, malignancy, or multiple hereditary conditions. Localized forms of the disease most often involve the skin, tracheobronchial tree, and urinary tract and typically require tissue sampling for diagnosis, as they may mimic many conditions including malignancy at imaging alone. Advancements in MRI and nuclear medicine have provided greater specificity for the diagnosis of amyloidosis involving the central nervous system and heart, potentially obviating the need for biopsy of the affected organ in certain circumstances. Specifically, a combination of characteristic findings at noninvasive cardiac MRI and skeletal scintigraphy in patients without an underlying plasma cell dyscrasia is diagnostic for cardiac transthyretin amyloidosis. Histologically, the presence of amyloid is denoted by staining with Congo red and a characteristic apple green birefringence under polarized light microscopy. The imaging features of amyloid vary across each organ system but share some common patterns, such as soft-tissue infiltration and calcification, that may suggest the diagnosis in the appropriate clinical context. The availability of novel therapeutics that target amyloid protein fibrils such as transthyretin highlights the importance of early diagnosis. Online supplemental material is available for this article. ©RSNA, 2021.


Subject(s)
Amyloid Neuropathies, Familial , Amyloid , Biopsy , Congo Red , Humans , Staining and Labeling
20.
Abdom Radiol (NY) ; 46(12): 5503-5508, 2021 12.
Article in English | MEDLINE | ID: mdl-34086093

ABSTRACT

Traditional teaching methods in radiology education have not kept pace with advances in technology that foster successful transition into independent practice. This deficit has been exacerbated by the COVID-19 pandemic, as the need for social distancing and the introduction of hybrid staffing models have decreased the critical educational interactions at the reading room workstations between staff and trainees. By leveraging interactive, case-based learning, educators have the opportunity to bridge the substantial gap between basic pattern recognition and successfully making a diagnosis in independent practice. For the educator, this signals a shift away from perfect case selection and presenter authority, and toward the role of a guide facilitating an active case-based learning experience. This form of learning is best accompanied by guided interpretation and iterative feedback with the goal of developing similar levels of mastery and autonomy among graduating trainees. In this article, we present the tools and methods for incorporating interactive cases into existing and novel teaching materials to meet the unique challenges educators are facing today.


Subject(s)
COVID-19 , Radiology , Humans , Pandemics , Radiography , SARS-CoV-2
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