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Analyst ; 139(24): 6357-60, 2014 Dec 21.
Article in English | MEDLINE | ID: mdl-25343163

ABSTRACT

CdTe nanocrystals capped by cysteamine were synthesized to study Cr(V)-induced genotoxicity. On the surface of TiO2 thin films, the stepwise process of DNA breakage induced by Cr(V)-GSH complexes was vividly observed by using CdTe-DNA self-assembled fluorescent probes; in acetate buffer solution, an analytical method was developed to detect Cr(V)-induced genotoxicity with CdTe fluorescent probes.


Subject(s)
Cadmium Compounds/chemistry , Chromates/toxicity , DNA Fragmentation/drug effects , Fluorescent Dyes/chemistry , Glutathione/toxicity , Mutagens/toxicity , Nanoparticles/chemistry , Tellurium/chemistry , Animals , Cattle , DNA/ultrastructure , Microscopy, Fluorescence
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