ABSTRACT
OBJECTIVE: to study the epidemiological profile of patients with colorectal cancer operated on an emergency basis at the Bonsucesso Federal Hospital. METHODS: this is a retrospective study of patients operated between January 1999 and December 2012. We analyzed the following variables: age, gender, clinical data, TMN staging, tumor location, survival and types of surgery. RESULTS: we evaluated 130 patients in the study period. The most frequent clinical picture was intestinal obstruction, in 78% of cases. Intestinal perforation was the surgical indication in 15%. The majority (39%) of the patients had advanced TNM staging, compared with 27% in the initial stage. There were 39 deaths (30%) documented in the period. The most common tumor site was the sigmoid colon (51%), followed by the ascending colon (16%). The curative intent was performed in most cases, with adjuvant treatment being performed in 40% of the patients. Distant metastases were found in 42% of the patients and 10% had documented disease recurrence. Disease-free survival at two and five years was 69% and 41%, respectively. CONCLUSION: there was a high mortality rate and a low survival rate in colorectal cancer patients operated on urgently.
Subject(s)
Colonic Neoplasms/epidemiology , Colonic Neoplasms/surgery , Emergency Treatment , Female , Humans , Male , Middle Aged , Retrospective Studies , Survival RateABSTRACT
ABSTRACT Objective: to study the epidemiological profile of patients with colorectal cancer operated on an emergency basis at the Bonsucesso Federal Hospital. Methods: this is a retrospective study of patients operated between January 1999 and December 2012. We analyzed the following variables: age, gender, clinical data, TMN staging, tumor location, survival and types of surgery. Results: we evaluated 130 patients in the study period. The most frequent clinical picture was intestinal obstruction, in 78% of cases. Intestinal perforation was the surgical indication in 15%. The majority (39%) of the patients had advanced TNM staging, compared with 27% in the initial stage. There were 39 deaths (30%) documented in the period. The most common tumor site was the sigmoid colon (51%), followed by the ascending colon (16%). The curative intent was performed in most cases, with adjuvant treatment being performed in 40% of the patients. Distant metastases were found in 42% of the patients and 10% had documented disease recurrence. Disease-free survival at two and five years was 69% and 41%, respectively. Conclusion: there was a high mortality rate and a low survival rate in colorectal cancer patients operated on urgently.
RESUMO Objetivos: estudar o perfil epidemiológico de pacientes com câncer colorretal operados em caráter de urgência no Hospital Federal de Bonsucesso. Métodos: estudo retrospectivo de pacientes operados entre janeiro de 1999 e dezembro de 2012. Foram analisadas as seguintes variáveis: idade, sexo, dados clínicos, estadiamento TMN, localização do tumor, sobrevida e tipos de cirurgia. Resultados: foram avaliados 130 pacientes no período do estudo. O quadro clínico mais observado foi a obstrução intestinal, em 78% dos casos. Perfuração intestinal foi a indicação cirúrgica em 15%. A maior parte (39%) dos pacientes apresentava estadiamento TNM avançado da doença, contra 27% em estágio inicial. Houve 39 óbitos (30%) documentados no período. A localização mais comum da doença foi no cólon sigmoide (51%), seguido do cólon ascendente (16%). A intenção curativa foi realizada na maioria dos casos, sendo o tratamento adjuvante realizado em 40% dos pacientes. Metástases à distância foram encontradas em 42% dos pacientes e 10% apresentaram recidiva documentada da doença. A sobrevida livre de doença em dois e cinco anos foi de 69% e 41% respectivamente. Conclusão: houve alta mortalidade e baixa sobrevida em pacientes com câncer colorretal operados de urgência.