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1.
Astrobiology ; 24(5): 489-497, 2024 May.
Article in English | MEDLINE | ID: mdl-38696654

ABSTRACT

Ribose is the defining sugar in ribonucleic acid (RNA), which is often proposed to have carried the genetic information and catalyzed the biological reactions of the first life on Earth. Thus, abiological processes that yield ribose under prebiotic conditions have been studied for decades. However, aqueous environments required for the formation of ribose from materials available in quantity under geologically reasonable models, where the ribose formed is not immediately destroyed, remain unclear. This is due in large part to the challenge of analysis of carbohydrates formed under a wide range of aqueous conditions. Thus, the formation of ribose on prebiotic Earth has sometimes been questioned. We investigated the quantitative effects of pH, temperature, cation, and the concentrations of formaldehyde and glycolaldehyde on the synthesis of diverse sugars, including ribose. The results suggest a range of conditions that produce ribose and that ribose could have formed in constrained aquifers on prebiotic Earth.


Subject(s)
Formaldehyde , Ribose , Temperature , Water , Ribose/chemistry , Hydrogen-Ion Concentration , Water/chemistry , Formaldehyde/chemistry , Acetaldehyde/chemistry , Acetaldehyde/analogs & derivatives , Earth, Planet , Origin of Life
2.
No Shinkei Geka ; 52(1): 213-225, 2024 Jan.
Article in Japanese | MEDLINE | ID: mdl-38246689

ABSTRACT

Industry-academia Collaboration is an academic activity within academia(educational institutions such as universities, research institutes, etc.)formed to research and develop new technologies, create new businesses and knowledge, and recruit outsourcing human resources. There is a collaboration between an industry(a private company, a group that engages in broad commercial activities and links research and development directly to economic activity)and academia. Amidst the dramatic changes in the environment surrounding the goals of research and development of new technologies and the creation of new businesses, there are changes in what academia can do complementarily. We will outline the changes and current situation, including the efforts of the Tohoku University Hospital.


Subject(s)
Academia , Industry
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