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1.
Case Rep Gastroenterol ; 4(2): 250-260, 2010 Jul 26.
Article in English | MEDLINE | ID: mdl-20805952

ABSTRACT

The most common tumors derived from the mesenchyme of the gastrointestinal system are stromal tumors. These tumors are typically seen in the stomach and small intestine and less frequently in the colon, rectum and esophagus and are very rarely located outside the gastrointestinal system. Cure is provided with complete surgical resection with resection borders free of tumor. Tumor size, mitotic index, localization, CD117 and CD34 negativity in immunohistochemical studies, mucosal ulceration and presence of necrosis help to predict recurrence of the illness and patient survival. In high-risk gastrointestinal stromal tumors (GISTs) there is an increased rate of recurrence and shortened survival despite complete surgical resection. Thus patients with a high-risk GIST should be given adjuvant therapy with imatinib mesylate. Sunitinib maleate is another FDA-approved agent only for cases who cannot tolerate imatinib or who are resistant to it. Herein we present three cases with GISTs in different locations of the gastrointestinal system with a review of the relevant literature.

2.
Surg Today ; 34(5): 437-9, 2004.
Article in English | MEDLINE | ID: mdl-15108083

ABSTRACT

Thyroidal hemiagenesis resulting from the failure of development of one thyroidal bud to develop accounts for fewer than 0.1% of thyroidal disorders necessitating surgery. This rare congenital anomaly usually occurs on the left side. Any nonfunctional lobe detected by scintigraphy needs to be evaluated further by ultrasonography, because thyroid hemiagenesis is associated with varying degrees of morbidity when it coexists with other anomalies requiring surgical intervention. We report the case of a 38-year-old woman with preoperatively diagnosed thyroidal hemiagenesis, who underwent surgery in our clinic. We review the literature in relation to this case, and discuss the problems and complications associated with this unusual congenital anomaly.


Subject(s)
Hyperthyroidism/etiology , Thyroid Gland/abnormalities , Thyroid Gland/surgery , Adult , Female , Humans , Hyperthyroidism/diagnostic imaging , Thyroid Gland/diagnostic imaging , Ultrasonography
3.
Ulus Travma Derg ; 8(3): 176-8, 2002 Jul.
Article in Turkish | MEDLINE | ID: mdl-12181764

ABSTRACT

A patient with blunt abdokminal trauma due to a traffic accident was admitted to our clinic and operated urgently because of hemodynamic shock. Operative exploration revealed rupture of a congenital giant cavernous liver hemangioma, then a partial hepatic resection was performed. Liver abscess and pleural effusion occurred in the postoperative period and the abscess was drained by a CT- guided cathetei: However the catheter drainage get infected. As a conclusion, if a liver hemangioma is detected incidentally on routine check-up studies, these people, carrying potential risk ofrupture should be warned about high risk jobs.


Subject(s)
Abdominal Injuries , Liver Neoplasms , Hemangioma , Humans , Liver Neoplasms/surgery , Wounds, Nonpenetrating
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