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BMJ Case Rep ; 13(9)2020 Sep 02.
Article in English | MEDLINE | ID: mdl-32878856

ABSTRACT

A 68-year-old woman presented with episodes of headache, palpitations, sweating and poorly controlled hypertension for the past 6 years. These symptoms were, at times, associated with micturition, and there were few episodes of micturition syncope as well. She had elevated 24-hour urinary normetanephrine and was found to have a paraganglioma arising from the urinary bladder infiltrating the sigmoid colon. She underwent laparotomy with excision of the bladder paraganglioma, following which her symptoms subsided. Paragangliomas are extra-adrenal catecholamine-producing tumours. Bladder paragangliomas need to be considered when evaluating hypertensive patients with headache, palpitations or syncope related to micturition.


Subject(s)
Paraganglioma/diagnosis , Syncope/etiology , Urinary Bladder Neoplasms/diagnosis , Urination/physiology , Aged , Cystectomy , Female , Humans , Normetanephrine/metabolism , Normetanephrine/urine , Paraganglioma/complications , Paraganglioma/physiopathology , Paraganglioma/surgery , Syncope/physiopathology , Syncope/surgery , Treatment Outcome , Ultrasonography , Urinary Bladder/diagnostic imaging , Urinary Bladder/pathology , Urinary Bladder/surgery , Urinary Bladder Neoplasms/complications , Urinary Bladder Neoplasms/physiopathology , Urinary Bladder Neoplasms/surgery
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