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J Med Case Rep ; 18(1): 264, 2024 May 30.
Article in English | MEDLINE | ID: mdl-38811941

ABSTRACT

BACKGROUND: Although 5-aminolevulinic acid is useful for the photodynamic diagnosis of bladder tumors, it often causes severe intraoperative hypotension. We report a case of postoperative cardiac arrest in addition to severe intraoperative hypotension, probably owing to the use of 5-aminolevulinic acid. CASE PRESENTATION: An 81-year-old Japanese man was scheduled to undergo transurethral resection of bladder tumor. The patient took 5-aminolevulinic acid orally 2 hours before entering the operating room. After the induction of anesthesia, his blood pressure decreased to 47/33 mmHg. The patient's hypotension did not improve even after noradrenaline was administered. After awakening from anesthesia, the patient's systolic blood pressure increased to approximately 100 mmHg, but approximately 5 hours after returning to the ward, cardiac arrest occurred for approximately 12 seconds. CONCLUSION: We experienced a case of postoperative cardiac arrest in a patient, probably owing to the use of 5-aminolevulinic acid. Although the cause of cardiac arrest is unknown, perioperative hemodynamic management must be carefully performed in patients taking 5-aminolevulinic acid.


Subject(s)
Aminolevulinic Acid , Heart Arrest , Hypotension , Postoperative Complications , Urinary Bladder Neoplasms , Humans , Male , Aminolevulinic Acid/adverse effects , Hypotension/etiology , Hypotension/chemically induced , Aged, 80 and over , Heart Arrest/etiology , Heart Arrest/chemically induced , Urinary Bladder Neoplasms/surgery , Photosensitizing Agents/adverse effects , Photosensitizing Agents/therapeutic use , Intraoperative Complications/chemically induced
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