1.
Chem Commun (Camb)
; 56(3): 399-402, 2020 Jan 02.
Article
in English
| MEDLINE
| ID: mdl-31820751
ABSTRACT
A combinatorial approach using a one-bead-one-compound method and a screening based on a SOD-activity assay was set up for the discovery of an efficient peptidyl copper complex. The complex exhibited good stability constants, suitable redox potentials and excellent intrinsic activity. This complex was further assayed in cells for its antioxidant properties and showed beneficial effects when cells were subjected to oxidative stress.