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Antimicrobial chemical constituents from the endophytic fungus Phomopsis sp. from Notobasis syriaca.
Nat Prod Commun
; 6(12): 1905-6, 2011 Dec.
Article
in English
| MEDLINE
| ID: mdl-22312735
ABSTRACT
Phomosine K (1), a new phomosine derivative, has been isolated from Phomopsis sp., in addition to six known compounds: phomosine A (2), phenylalanine amide (3), 2-hydroxymethyl-4beta,5alpha,6beta-trihydroxycyclohex-2-en (4), (-)-phyllostine (5), (+)-epiepoxydon (6), and (+)-epoxydon monoacetate (7). Preliminary studies showed that compound 1 had strong antibacterial activity, while compounds 4-7 showed good antifungal, antibacterial, and algicidal properties, except compounds 4 and 6, which lacked antifungal activity.