ABSTRACT
Primary cardiac tumor is uncommon in childhood, with an incidence of 0.06-0.32%, and intrapericardial teratoma represents an exceptional rarity among these entities. Germ cell tumors (GCT) are rare, representing only 1-3% of childhood tumors. Twenty per cent of GCT are malignant and are associated with age and location. Extragonadal involvement accounts for nearly half of the cases. Anterior mediastinum is a common location of malignant germ cell tumors, yet pericardial and aortic adventitia involvement have been rarely reported. Here we report the case of a preterm twin baby boy with intrapericardial mixed germ cell tumor who presented with hydrops fetalis and pericardial effusion.
Subject(s)
Diseases in Twins , Heart Neoplasms/complications , Infant, Premature , Neoplasms, Germ Cell and Embryonal/complications , Pericardial Effusion/etiology , Twins , Cardiac Surgical Procedures/methods , Echocardiography , Electrocardiography , Female , Follow-Up Studies , Heart Neoplasms/diagnosis , Heart Neoplasms/surgery , Humans , Infant, Newborn , Male , Neoplasms, Germ Cell and Embryonal/diagnosis , Neoplasms, Germ Cell and Embryonal/surgery , Pericardial Effusion/diagnosis , Pericardial Effusion/surgery , Pericardiocentesis , Pregnancy , Ultrasonography, PrenatalABSTRACT
BACKGROUND: This study was undertaken to assess the value of neutrophils CD11b, CD64, and CD62L for the early diagnosis of neonatal infection. METHODS: Eighty-four neonates who were followed up for a suspected neonatal infection were included in this study. They were assigned into an infection group (n=49) and a non-infection group (n=35). Healthy neonates served as controls (n=35). A full sepsis screening was performed and neutrophil and monocyte expressions of CD11b, CD64 and CD62L were determined by flow cytometry. RESULTS: The expressions of CD64 and CD11b were significantly enhanced in the infection group compared to the non-infective group and the controls. CONCLUSIONS: CD64 expression on neutrophils and monocytes is a useful diagnostic marker for the early diagnosis of neonatal infection. Combination of CD64, CD11b and C reactive protein further enhances the sensitivity of the expression and its negative predictive value.