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The use of Vaccinia Immune Globulin in the Treatment of Severe Mpox. Virus Infection in Human Immunodeficiency Virus/AIDS.
Thet, Andrea K; Kelly, Paul J; Kasule, Sabirah N; Shah, Anish K; Chawala, Arpan; Latif, Amber; Chilimuri, Sridhar S; Zeana, Cosmina B.
Clin Infect Dis ; 76(9): 1671-1673, 2023 05 03.
Article in English | MEDLINE | ID: mdl-36571287

ABSTRACT

We report a case of progressive, severe mpox virus (MPXV) infection in a patient with AIDS despite a standard course of tecovirimat. He significantly improved after administration of vaccinia immune globulin intravenous (VIGIV) highlighting its use as an adjunct for severe disease in immunocompromised hosts.


Subject(s)
Acquired Immunodeficiency Syndrome , Mpox (monkeypox) , Vaccinia , Male , Humans , Vaccinia/therapy , HIV , Immunoglobulins , Immunologic Factors
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