ABSTRACT
OBJECTIVE: This study aimed to evaluate the sensitivity of transient evoked otoacoustic emission testing as a screening tool for hearing loss in children, after grommet insertion. METHOD: A prospective study was conducted of 48 children (91 ears) aged three to 16 years who had undergone grommet insertion for glue ear. At post-operative review, pure tone audiometry was performed followed by transient evoked otoacoustic emission testing. Outcomes for both tests, in each ear, were compared. RESULTS: The pure tone audiometry threshold was ≤ 20 dB in 85 ears (93.4 per cent), 25 dB in two ears (2.2 per cent) and ≥ 30 dB in four ears (4.4 per cent). Transient evoked otoacoustic emissions were detected in 69 ears (75.8 per cent). The sensitivity of transient evoked otoacoustic emission testing for detecting hearing loss was 100 per cent for ≥ 30 dB loss but only 66.7 per cent for ≥ 25 dB loss. CONCLUSION: Transient evoked otoacoustic emission testing offers a sensitive means of detecting hearing loss of ≥ 30 dB following grommet insertion in children. However, the use of such testing as a screening tool may miss some cases of mild hearing loss.
Subject(s)
Audiometry, Pure-Tone/methods , Evoked Potentials, Auditory/physiology , Hearing Loss/diagnosis , Middle Ear Ventilation , Otitis Media with Effusion/surgery , Adolescent , Age Factors , Auditory Threshold/physiology , Child , Child, Preschool , Hearing Loss/physiopathology , Humans , Otitis Media with Effusion/physiopathology , Otoscopy , Patient Compliance , Postoperative Care/methods , Prospective Studies , Sensitivity and Specificity , United KingdomABSTRACT
OBJECTIVE: The aim of this report was to highlight the fact that hearing loss in thalassaemia patients can be related to marrow expansion affecting the ossicles, resulting in a conductive loss. CASE REPORT: A six-year-old boy with transfusion-dependent beta-thalassaemia developed a unilateral hearing loss shortly after commencing desferrioxamine therapy. Ototoxicity was assumed, but the deficit was later found to be of a conductive nature, due to marrow proliferation within the ossicular chain as a consequence of the disease process--a phenomenon previously unreported in the literature. CONCLUSION: It is important to elucidate the precise nature of new onset hearing loss in patients receiving iron chelation therapy, in order to avoid unnecessary cessation of much needed medication, on the assumption of ototoxicity.
Subject(s)
Bone Marrow Diseases/complications , Deferoxamine/adverse effects , Hearing Loss/chemically induced , Siderophores/adverse effects , beta-Thalassemia/drug therapy , Child , Humans , MaleABSTRACT
Lower limb ulcers present a common clinical problem and are at risk of malignant change. A Marjolin's ulcer has traditionally been regarded as malignant change in a long standing ulcer and/or scar tissue. We report a case of Marjolin's degeneration that developed in an ulcer only 18 months following the initial injury. Such a short latent period has not been reported for over 70 years. This report highlights the possibility of early Marjolin's change and we propose a ranked diagnostic screen to aid in early identification of possible malignant change, based on the current published evidence.
Subject(s)
Carcinoma, Squamous Cell/surgery , Leg Ulcer/complications , Skin Neoplasms/surgery , Aged , Carcinoma, Squamous Cell/pathology , Cell Transformation, Neoplastic/pathology , Humans , Male , Skin Neoplasms/pathology , Skin Transplantation/methods , Treatment Outcome , Wound Healing/physiologyABSTRACT
Paranasal sinus mucoceles are benign, locally expansile cyst-like masses that are filled with mucus and lined with epithelium. Less than one per cent of them involve the maxillary sinus. Most of these are late complications of a Caldwell Luc procedure. A case is presented of a 31-year-old woman with a maxillary sinus mucocele who had undergone a Le Fort I maxillary advancement procedure 15 years previously - a complication never previously reported.