The Structural Response of the Human Head to a Vertex Impact.

In experimental models of cervical spine trauma caused by near-vertex head-first impact, a surrogate headform may be substituted for the cadaveric head. To inform headform design and to verify that such substitution is valid, the force-deformation response of the human head with boundary conditions relevant to cervical spine head-first impact models is required. There are currently no biomechanics data that characterize the force-deformation response of the isolated head supported at the occiput and compressed at the vertex by a flat impactor. The effect of impact velocity (1, 2 or 3 m/s) on the response of human heads (N = 22) subjected to vertex impacts, while supported by a rigid occipital mount, was investigated. 1 and 2 m/s impacts elicited force-deformation responses with two linear regions, while 3 m/s impacts resulted in a single linear region and skull base ring fractures. Peak force and stiffness increased from 1 to 2 and 3 m/s. Deformation at peak force and absorbed energy increased from 1 to 2 m/s, but decreased from 2 to 3 m/s. The data reported herein enhances the limited knowledge on the human head's response to a vertex impact, which may allow for validation of surrogate head models in this loading scenario.

A Review of the Compressive Stiffness of the Human Head.

Synthetic surrogate head models are used in biomechanical studies to investigate skull, brain, and cervical spine injury. To ensure appropriate biofidelity of these head models, the stiffness is often tuned so that the surrogate's response approximates the cadaveric response corridor. Impact parameters such as energy, and loading direction and region, can influence injury prediction measures, such as impact force and head acceleration. An improved understanding of how impact parameters affect the head's structural response is required for designing better surrogate head models. This study comprises a synthesis and review of all existing ex vivo head stiffness data, and the primary factors that influence the force-deformation response are discussed. Eighteen studies from 1972 to 2019 were identified. Head stiffness statistically varied with age (pediatric vs. adult), loading region, and rate. The contact area of the impactor likely affects stiffness, whereas the impactor mass likely does not. The head's response to frontal impacts was widely reported, but few studies have evaluated the response to other impact locations and directions. The findings from this review indicate that further work is required to assess the effect of head constraints, loading region, and impactor geometry, across a range of relevant scenarios.

The Effect of Axial Compression and Distraction on Cervical Facet Cartilage Apposition During Shear and Bending Motions.

During cervical spine trauma, complex intervertebral motions can cause a reduction in facet joint cartilage apposition area (CAA), leading to cervical facet dislocation (CFD). Intervertebral compression and distraction likely alter the magnitude and location of CAA, and may influence the risk of facet fracture. The aim of this study was to investigate facet joint CAA resulting from intervertebral distraction (2.5 mm) or compression (50, 300 N) superimposed on shear and bending motions. Intervertebral and facet joint kinematics were applied to multi rigid-body kinematic models of twelve C6/C7 motion segments (70 ± 13 year, nine male) with specimen-specific cartilage profiles. CAA was qualitatively and quantitatively compared between distraction and compression conditions for each motion; linear mixed-effects models (α = 0.05) were applied. Distraction significantly decreased CAA throughout all motions, compared to the compressed conditions (p < 0.001), and shifted the apposition region towards the facet tip. These observations were consistent bilaterally for both asymmetric and symmetric motions. The results indicate that axial neck loads, which are altered by muscle activation and head loading, influences facet apposition. Investigating CAA in longer cervical spine segments subjected to quasistatic or dynamic loading may provide insight into dislocation and fracture mechanisms.

Estimating Facet Joint Apposition with Specimen-Specific Computer Models of Subaxial Cervical Spine Kinematics.

Computational models of experimental data can provide a noninvasive method to estimate spinal facet joint biomechanics. Existing models typically consider each vertebra as one rigid-body and assume uniform facet cartilage thickness. However, facet deflection occurs during motion, and cervical facet cartilage is nonuniform. Multi rigid-body computational models were used to investigate the effect of specimen-specific cartilage profiles on facet contact area estimates. Twelve C6/C7 segments underwent non-destructive intervertebral motions. Kinematics and facet deflections were measured. Three-dimensional models of the vertebra and cartilage thickness estimates were obtained from pre-test CT data. Motion-capture data was applied to two model types (2RB: C6, C7 vertebrae each one rigid body; 3RB: left and right C6 posterior elements, and C7 vertebrae, each one rigid body) and maximum facet mesh penetration was compared. Constant thickness cartilage (CTC) and spatially-varying thickness cartilage (SVTC) profiles were applied to the facet surfaces of the 3RB model. Cartilage apposition area (CAA) was compared. Linear mixed-effects models were used for all quantitative comparisons. The 3RB model significantly reduced penetrating mesh elements by accounting for facet deflections (p = 0.001). The CTC profile resulted in incongruent facet articulation, whereas realistic congruence was observed for the SVTC profile. The SVTC profile demonstrated significantly larger CAA than the CTC model (p < 0.001).