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1.
Pharmacol Biochem Behav ; 239: 173756, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38555037

ABSTRACT

Prenatal opioid exposure (POE) and postnatal adverse experiences are early life adversities (ELA) that often co-occur and increase problematic alcohol (EtOH) drinking during adolescence. We investigated the relationship between POE, postnatal adversity, and adolescent EtOH drinking in rats. We also sought to determine whether ELAs affect alpha-adrenoceptor density in the brain because the noradrenergic system is involved in problematic alcohol drinking and its treatment. We hypothesized that the combination of POE and postnatal adversity will increase alcohol drinking in rats compared to rats with exposure to either adversity alone or to control. We also predicted that POE and postnatal adversity would increase α1-adrenoceptor density and decrease α2-adrenoceptor density in brain to confer a stress-responsive phenotype. Pregnant rats received morphine (15 mg/kg/day) or saline via subcutaneous minipumps from gestational day 9 until birth. Limited bedding and nesting (LBN) procedures were introduced from postnatal day (PD) 3-11 to mimic early life adversity-scarcity. Offspring rats (PD 31-33) were given opportunities to drink EtOH (20 %, v/v) using intermittent-access, two-bottle choice (with water) procedures. Rats given access to EtOH were assigned into sub-groups that were injected with either yohimbine (1 mg/kg, ip) or vehicle (2 % DMSO, ip) 30 min prior to each EtOH access session to determine the effects of α2-adrenoceptor inhibition on alcohol drinking. We harvested cortices, brainstems, and hypothalami from EtOH-naïve littermates on either PD 30 or PD 70 and conducted radioligand receptor binding assays to quantify α1- and α2-adrenoceptor densities. Contrary to our hypothesis, only LBN alone increased EtOH intake in female adolescent rats compared to female rats with POE. Neither POE nor LBN affected α1- or α2-adrenoceptor densities in the cortex, brainstem, or hypothalamus of early- or late-aged adolescent rats. These results suggest a complex interaction between ELA type and sex on alcohol drinking.


Subject(s)
Alcohol Drinking , Ethanol , Prenatal Exposure Delayed Effects , Animals , Female , Rats , Pregnancy , Alcohol Drinking/metabolism , Prenatal Exposure Delayed Effects/metabolism , Ethanol/administration & dosage , Ethanol/pharmacology , Male , Receptors, Adrenergic, alpha-2/metabolism , Morphine/pharmacology , Brain/metabolism , Brain/drug effects , Receptors, Adrenergic, alpha-1/metabolism , Rats, Sprague-Dawley
2.
Psychol Rep ; 116(1): 116-26, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25621674

ABSTRACT

A Latvian version of the Revised Paranormal Belief Scale (RPBS) was completed by 229 Latvian university students. Exploratory and confirmatory factor analyses revealed six relatively independent factors labeled Magical Abilities, Psychokinesis, Traditional Religious Belief, Superstition, Spirit Travel, and Extraordinary Life Forms. Based on the motivational-control model, it was hypothesized that the societal stressors affecting Latvian society during the last 50 yr. have led to a reduced sense of personal control which, in turn, has resulted in increased endorsement of paranormal beliefs to re-establish a sense of control. The motivational-control hypothesis was not supported. Results indicated that (except for Traditional Religious Belief in women), the majority of these students were disbelievers in paranormal phenomena. As hypothesized, Latvian women reported significantly greater paranormal belief than men.


Subject(s)
Psychometrics/instrumentation , Students/psychology , Superstitions/psychology , Surveys and Questionnaires/standards , Adult , Female , Humans , Latvia/ethnology , Male , Universities , Young Adult
3.
Psychol Rep ; 82(2): 481-2, 1998 Apr.
Article in English | MEDLINE | ID: mdl-9621723

ABSTRACT

Reporters of out-of-body experiences (n = 21) and nonreporters (n = 159) showed no significant differences on the Spheres of Control Scale, Self-efficacy Scale, and Purpose in Life Scale. However, reporters of out-of-body experiences showed significantly greater belief in Psi, Spiritualism, and Extraordinary Life Forms than nonreporters.


Subject(s)
Culture , Depersonalization/psychology , Mind-Body Relations, Metaphysical , Self Concept , Adult , Female , Humans , Male
4.
J Soc Psychol ; 130(1): 47-51, 1990 Feb.
Article in English | MEDLINE | ID: mdl-2325400

ABSTRACT

The lunar hypothesis, that is, the notion that lunar phases can directly affect human behavior, was tested by time-series analysis of 4,575 crisis center telephone calls (all calls recorded for a 6-month interval). As expected, the lunar hypothesis was not supported. The 28-day lunar cycle accounted for less than 1% of the variance of the frequency of crisis center calls. Also, as hypothesized from an attribution theory framework, crisis center workers reported significantly greater belief in lunar effects than a non-crisis-center-worker comparison group.


Subject(s)
Crisis Intervention , Hotlines/statistics & numerical data , Periodicity , Adult , Humans , Louisiana
5.
Psychol Rep ; 62(2): 434, 1988 Apr.
Article in English | MEDLINE | ID: mdl-3406257
6.
J Nerv Ment Dis ; 175(6): 367-70, 1987 Jun.
Article in English | MEDLINE | ID: mdl-3585314

ABSTRACT

Relationships between the out-of-body experience and personality adjustment were studied. A total of 445 college students, including 65 reporting out-of-body experiences, completed self-report measures of death orientation, defensive style, narcissism, paranormal beliefs, self-concept, and social desirability. No significant differences were found between respondents reporting out-of-body experiences and nonreporters on any of the instruments, except for the Paranormal Belief Scale. Reporters of out-of-body experiences showed significantly greater belief in precognition, psi, spiritualism, and witchcraft than did nonreporters. Findings indicate considerable similarity between reporters and nonreporters in personality adjustment. It is clear that, on these personality adjustment measures, the out-of-body experience was associated with neither less effective nor more effective adjustment.


Subject(s)
Mental Health , Parapsychology , Personality , Adult , Attitude to Death , Female , Humans , Magic , Male , Narcissism , Personality Inventory , Self Concept , Social Desirability
10.
J Pers Assess ; 47(6): 648-55, 1983 Dec.
Article in English | MEDLINE | ID: mdl-6663439

ABSTRACT

Data on a brief mental status schedule (Memory Check) and a behavior rating scale of mental impairment (Functional Behavior Survey) are presented which support the use of these instruments in research and survey work with both community and institutionalized aged. Based on a factorially derived concept of mental competence, the two instruments showed a satisfactory relation to clinical judgment of degree of competence, and also to a composite measure of nine test measures commonly used in assessing mental competence. The sample consisted of 68 community and nursing home residents between the ages of 60 and 80 who ranged from those who were unimpaired to those judged clinically to be grossly mentally impaired.


Subject(s)
Dementia/diagnosis , Psychological Tests , Activities of Daily Living , Aged , Dementia/psychology , Female , Humans , Male , Middle Aged , Psychometrics , Social Adjustment
11.
Psychol Rep ; 51(3 Pt 1): 861-2, 1982 Dec.
Article in English | MEDLINE | ID: mdl-7163441
12.
J Pers Assess ; 45(3): 270-7, 1981 Jun.
Article in English | MEDLINE | ID: mdl-16370713

ABSTRACT

College students (122 males and 88 females) completed the Group Embedded Figures Test measure of field-dependence, and Sensation-Seeking Scale, and performed preference ratings on 40 slides of paintings. Factor analysis revealed six hypothesized and one unhypothesized preference dimensions that underlay preference ratings of paintings. It was hypothesized that the cognitive structuring ability associated with field-dependence would result in certain relationships between field-dependence and preference for paintings. Further, it was hypothesized that preference for novel, complex, and dynamic experiences, associated with sensation-seeking, would result in certain relationships between sensation-seeking and preference for paintings. For the full sample, three of five hypothesized relationships between field-dependence and preference for paintings were obtained, while three of four hypothesized relationships were found between sensation-seeking and preference for paintings.

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