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3.
Arch. Soc. Esp. Oftalmol ; 94(8): 391-395, ago. 2019. ilus
Article in Spanish | IBECS | ID: ibc-185625

ABSTRACT

Se trata de un hombre de 45 años con cierre angular y miopía aguda bilateral tras inicio de tratamiento con topiramato por dependencia al alcohol y la heroína. La tomografía de coherencia óptica Visante(R) y la ecografía ocular muestran efusión ciliocoroidea bilateral como mecanismo fisiopatológico. El tratamiento consistió en la retirada del topiramato, y la utilización de hipotensores oculares, ciclopléjico y corticoides tópicos, con lo cual se resolvió el síndrome de efusión ciliocoroidea. La tomografía de coherencia óptica Visante(R) y la ecografía ocular son herramientas útiles en el diagnóstico y seguimiento de los pacientes con cierre angular y miopía en el contexto del síndrome de efusión ciliocoroidea secundario a topiramato. Debido al amplio espectro de indicaciones de esta medicación, tanto el personal sanitario que lo indica como los oftalmólogos, deben conocer las posibles manifestaciones oculares atribuidas a este medicamento


A 45 year-old man with bilateral acute angle-closure and myopia after starting treatment with topiramate, secondary to alcohol and heroin dependence. Using Visante(R) OCT (Optical Coherence Tomography) and B-scan Ultrasound he was diagnosed with bilateral ciliochoroidal effusion as the pathophysiological mechanism. Topiramate was stopped and ocular hypotensive therapy with a topical cycloplegic and corticosteroids were started, resolving ciliochoroidal effusion syndrome. Visante(R) OCT and B-scan Ultrasound are useful tools for the diagnosis and follow-up of patients with acute angle-closure and myopia due to topiramate. As a result of broad spectrum of indications for topiramate, physicians and ophthalmologists should be aware of the possible ophthalmological manifestations attributable to this drug


Subject(s)
Humans , Male , Middle Aged , Anticonvulsants/adverse effects , Microscopy, Acoustic/methods , Tomography, Optical Coherence/methods , Topiramate/adverse effects , Adrenal Cortex Hormones/therapeutic use , Alcoholism , Follow-Up Studies , Glaucoma, Angle-Closure/chemically induced , Glaucoma, Angle-Closure/diagnostic imaging , Glaucoma, Angle-Closure/drug therapy , Heroin Dependence , Mydriatics/therapeutic use , Myopia/chemically induced , Myopia/drug therapy
4.
Arch Soc Esp Oftalmol (Engl Ed) ; 94(8): 391-395, 2019 Aug.
Article in English, Spanish | MEDLINE | ID: mdl-30738599

ABSTRACT

A 45 year-old man with bilateral acute angle-closure and myopia after starting treatment with topiramate, secondary to alcohol and heroin dependence. Using Visante® OCT (Optical Coherence Tomography) and B-scan Ultrasound he was diagnosed with bilateral ciliochoroidal effusion as the pathophysiological mechanism. Topiramate was stopped and ocular hypotensive therapy with a topical cycloplegic and corticosteroids were started, resolving ciliochoroidal effusion syndrome. Visante® OCT and B-scan Ultrasound are useful tools for the diagnosis and follow-up of patients with acute angle-closure and myopia due to topiramate. As a result of broad spectrum of indications for topiramate, physicians and ophthalmologists should be aware of the possible ophthalmological manifestations attributable to this drug.


Subject(s)
Anticonvulsants/adverse effects , Choroidal Effusions/diagnostic imaging , Microscopy, Acoustic/methods , Tomography, Optical Coherence/methods , Topiramate/adverse effects , Adrenal Cortex Hormones/therapeutic use , Alcoholism , Choroidal Effusions/complications , Choroidal Effusions/drug therapy , Follow-Up Studies , Glaucoma, Angle-Closure/chemically induced , Glaucoma, Angle-Closure/diagnostic imaging , Glaucoma, Angle-Closure/drug therapy , Heroin Dependence , Humans , Male , Middle Aged , Mydriatics/therapeutic use , Myopia/chemically induced , Myopia/drug therapy
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