ABSTRACT
INTRODUCTION: Bariatric surgery aims to reduce weight and resolve the comorbidities associated with obesity. Few studies have assessed mid/long-term changes in lipid profile with sleeve gastrectomy versus gastric bypass. This study was conducted to assess and compare changes in lipid profile with each procedure after 60 months. METHODS: This was an observational, retrospective study of analytical cohorts enrolling 100 patients distributed into two groups: 50 had undergone gastric bypass (GBP) surgery and 50 sleeve gastrectomy (SG) surgery. Total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglyceride (TG) levels were measured before surgery and at 1, 6, 12, 24, 36, 48, and 60 months. Weight loss and the resolution of dyslipidemia with each of the procedures were also assessed. RESULTS: Ninety-five of the 100 patients completed follow-up. At 60 months, TC and LDL levels had significantly decreased in the BPG group (167.42⯱â¯31.22â¯mg/dl and 88.06⯱â¯31.37â¯mg/dl, respectively), while there were no differences in the SG group. Increased HDL levels were seen with both procedures (BPG: 62.69⯱â¯16.3â¯mg/dl vs. SG: 60.64⯱â¯18.73â¯mg/dl), with no difference between the procedures. TG levels decreased in both groups (BPG: 86.06⯱â¯56.57â¯mg/dl vs. SG: 111.09⯱â¯53.08â¯mg/dl), but values were higher in the BPG group (Pâ¯<â¯.05). The percentage of overweight lost (PSP) was higher in the BPG group: 75.65⯱â¯22.98â¯mg/dl vs. the GV group: 57.83⯱â¯27.95â¯mg/dl. CONCLUSION: Gastric bypass achieved better mid/long-term results in terms of weight reduction and the resolution of hypercholesterolemia as compared to sleeve gastrectomy. While gastric bypass improved all lipid profile parameters, sleeve gastrectomy only improved HDL and triglyceride levels.
Subject(s)
Bariatric Surgery , Gastric Bypass , Lipids/blood , Obesity, Morbid , Gastrectomy , Humans , Lipoproteins, HDL/blood , Obesity, Morbid/surgery , Retrospective Studies , Triglycerides/blood , Weight LossABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Gastroesophageal Reflux/diagnostic imaging , Gastroesophageal Reflux/surgery , Laparoscopy/methods , Gastroscopy/instrumentation , Gastroscopy/methods , Biopsy , Hyaluronic Acid/administration & dosage , Chondroitin/administration & dosage , Duodenum/surgerySubject(s)
Duodenal Obstruction/complications , Duodenum/surgery , Gastric Bypass/methods , Gastroesophageal Reflux/complications , Intestinal Atresia/complications , Laparoscopy/methods , Stomach Ulcer/complications , Vagotomy, Truncal/methods , Aged , Duodenal Obstruction/surgery , Gastroesophageal Reflux/diagnostic imaging , Gastroesophageal Reflux/surgery , Gastroscopy , Humans , Intestinal Atresia/surgery , Male , Stomach Ulcer/diagnostic imaging , Stomach Ulcer/surgeryABSTRACT
No disponible
Subject(s)
Humans , Male , Aged, 80 and over , Intestinal Obstruction/complications , Diverticulum/complications , Intestinal Volvulus/diagnosis , Jejunal Diseases/complications , Incidental Findings , Diverticulum/surgerySubject(s)
Diverticulum/complications , Intestinal Obstruction/etiology , Jejunal Diseases/etiology , Abdominal Pain/etiology , Aged, 80 and over , Diverticulum/diagnostic imaging , Diverticulum/surgery , Fatal Outcome , Humans , Intestinal Obstruction/diagnostic imaging , Intestinal Obstruction/surgery , Ischemia/etiology , Jejunal Diseases/diagnostic imaging , Jejunal Diseases/surgery , Jejunum/blood supply , Male , Postoperative Complications/etiology , Pulmonary Edema/etiologyABSTRACT
No disponible