A New Collaborative Classification Process for Microcalcification Detection Based on Graphs and Knowledge Propagation.

In this paper, we propose a new collaborative process that aims to detect macrocalcifications from mammographic images while minimizing false negative detections. This process is made up of three main phases: suspicious area detection, candidate object identification, and collaborative classification. The main concept is to operate on the entire image divided into homogenous regions called superpixels which are used to identify both suspicious areas and candidate objects. The collaborative classification phase consists in making the initial results of different microcalcification detectors collaborate in order to produce a new common decision and reduce their initial disagreements. The detectors share the information about their detected objects and associated labels in order to refine their initial decisions based on those of the other collaborators. This refinement consists of iteratively updating the candidate object labels of each detector following local and contextual analyses based on prior knowledge about the links between super pixels and macrocalcifications. This process iteratively reduces the disagreement between different detectors and estimates local reliability terms for each super pixel. The final result is obtained by a conjunctive combination of the new detector decisions reached by the collaborative process. The proposed approach is evaluated on the publicly available INBreast dataset. Experimental results show the benefits gained in terms of improving microcalcification detection performances compared to existing detectors as well as ordinary fusion operators.

A new conditional region growing approach for microcalcification delineation in mammograms.

Microcalcifications (MCs) are considered as the first indicator of breast cancer development. Their morphology, in terms of shape and size, is considered as the most important criterion that determines their malignity degrees. Therefore, the accurate delineation of MC is a cornerstone step in their automatic diagnosis process. In this paper, we propose a new conditional region growing (CRG) approach with the ability of finding the accurate MC boundaries starting from selected seed points. The starting seed points are determined based on regional maxima detection and superpixel analysis. The region growing step is controlled by a set of criteria that are adapted to MC detection in terms of contrast and shape variation. These criteria are derived from prior knowledge to characterize MCs and can be divided into two categories. The first one concerns the neighbourhood searching size. The second one deals with the analysis of gradient information and shape evolution within the growing process. In order to prove the effectiveness and the reliability in terms of MC detection and delineation, several experiments have been carried out on MCs of various types, with both qualitative and quantitative analysis. The comparison of the proposed approach with state-of-the art proves the importance of the used criteria in the context of MC delineation, towards a better management of breast cancer. Graphical Abstract Flowchart of the proposed approach.

Tunisian Recommendations for resumption of Reproductive Medicine activity in the Covid-19 pandemic.

The activity of the Reproductive Medicine poses a dilemma in this pandemic Covid-19. In fact, this is a theoretically non-emergency activity except for fertility preservation with oncological reasons. The majority of fertility societies in the world such as the American Society for Reproductive Medicine (ASRM) and the European Society of Human Reproduction and Embryology (ESHRE) recommended stopping the inclusion of new patients and continuing only the In Vitro Fertilization (IVF) cycles that have already been initiated by promoting Freeze-all as much as possible. Initilaly, the "Société Tunisienne de Gynécologie Obstétrique" (STGO) issued national recommendations that echo the international recommendations. These recommendations were followed by the majority of IVF center in Tunisia. However, a number of new data are prompting us to update these recommendations.

Iterative fuzzy segmentation for an accurate delimitation of the breast region.

In mammographic images, extracting different anatomical structures and tissues types is a critical requirement for the breast cancer diagnosis. For instance, separating breast and background regions increases the accuracy and efficiency of mammographic processing algorithms. In this paper, we propose a new region-based method to properly segment breast and background regions in mammographic images. These regions are estimated by an Iterative Fuzzy Breast Segmentation method (IFBS). Based on the Fuzzy C-Means (FCM) algorithm, IFBS method iteratively increases the precision of an initially extracted breast region. This proposal is evaluated using the MIAS database. Experimental results show high accuracy and reliability in breast extraction when compared with Ground-Truth (GT) images.