ABSTRACT
Laparoscopic surgical repair of perforated gastroduodenal ulcer is technically feasible. To study the effect of a pneumoperitoneum on the extent and severity of peritonitis this animal study was devised. In rats gastric ulceration was induced by instillation of ethanol (50%, 2 ml) and followed by gastrotomy to simulate perforation. Animals were randomly allocated to pneumoperitoneum (PP) and control groups. In PP groups CO2 was insufflated intraperitoneally 6, 9, 12, and 24 h after gastrotomy. In controls the abdomen was only punctured. Animals were sacrificed 5 h after the end of PP or abdominal puncture. Blood cultures and intraabdominal swabs were assessed. A peritonitis severity score (PSS) based on histologies from peritoneum, liver, left kidney, spleen, and first jejunal loop was estimated. Six and 9 h after gastrotomy no significant differences between the PP and control groups were observed; 12 h after gastrotomy cultures of blood samples and abdominal swabs were positive in 67% and 75% in the PP group compared to 42% (P < 0.05), and 42% (P < 0.05) in controls. The mean PSS was 20.8 (standard deviation [SD] 2.2) in the PP group compared to 11.3 (1.5) (P < 0.01) in controls; 24 h after gastrotomy cultures of blood samples and abdominal swabs were positive in 83% and 100% in the PP group compared to 42% (P < 0.05) and 50% (P < 0.01) in controls. The mean PSS was 22.1 (1.5) in the PP group compared to 11.8 (2.4) (P < 0.01) in the controls.(ABSTRACT TRUNCATED AT 250 WORDS)
Subject(s)
Peptic Ulcer Perforation/complications , Peritonitis/etiology , Pneumoperitoneum/physiopathology , Stomach Ulcer/complications , Animals , Female , Laparoscopy , Peritonitis/microbiology , Peritonitis/pathology , Pneumoperitoneum/etiology , Random Allocation , Rats , Rats, Wistar , Risk , Severity of Illness Index , Time FactorsABSTRACT
A solid-cystic acinar cell tumour of the pancreas was found in four female patients. This particular form of benign pancreatic tumour is characteristically found in young women, often reaches a large size (2.5-10 cm), presents as a spherical mass in computed tomography or ultrasonography and does not show infiltrative growth or metastases. Tumours can be readily enucleated or resected. This type of tumour does not yet appear in the WHO classification of epithelial pancreatic tumours. It probably arises from the acinar cells. Accurate differentiation from previously known highly malignant acinar tumours is absolutely necessary on account of the good prognosis of this type of tumour.
Subject(s)
Adenoma/surgery , Adrenal Gland Neoplasms/surgery , Pancreatic Neoplasms/pathology , Adolescent , Adrenal Gland Neoplasms/complications , Adult , Female , Humans , Neoplasm Invasiveness , Ovarian Neoplasms/complications , Ovarian Neoplasms/surgery , Pancreatic Neoplasms/complications , Pancreatic Neoplasms/surgerySubject(s)
Freezing , Insemination, Artificial/veterinary , Spermatozoa/physiology , Swine/physiology , Animals , Female , Male , Sperm Motility , Tissue Preservation/methodsSubject(s)
Dogs/physiology , Fertility , Animals , Body Weight , Ejaculation , Heterozygote , Homozygote , Male , Organ Size , Pigmentation , Sexual Behavior, Animal , Sperm Motility , Spermatozoa/pathology , Spermatozoa/physiology , Testis/physiologyABSTRACT
Artificial insemination using deep-frozen semen was performed on 116 mares in 1973 using twelve ejaculates from eight stallions of the Hanoverian breed. Despite the fact that the quality of the semen used was poor, the majority of the mares inseminated were subfertile and some mares were inseminated during one oestrus only, 44% nevertheless conceived and gave birth to live foals. Of a small group of ten mares inseminated in the same year with fresh semen, seven conceived.
