ABSTRACT
OBJECTIVE: Mycoplasma genitalium is an emerging cause of sexually transmitted infections (STIs) and has been implicated in non-gonococcal urethritis in men and cervicitis in woman. The aim of this study is determinate the incidence and pathogenicity of M. genitalium within the diagnosis of STIs detected from clinical samples in a third level hospital. METHODS: A total of 8,473 samples from endocervix, urethra, vagina, rectum and others were processed applying Allpex STI Essential Assay. More than 190 records were reviewed to determinate M. genitalium pathogenicity. RESULTS: M. genitalium was detected in a rate 2.8%. Co-infections were detected in 20% of the patients. CONCLUSIONS: M. genitalium is considered a STI emerging pathogen thanks to the renewal of multiplex-PCR tests although with a low incidence in our approach. Emerging from our experience and the institutional recommendations both detection of acid nucleic techniques (NAATs) and gonococcal culture might be implemented accurately and coexist to adequate prescriptions.
Subject(s)
Mycoplasma Infections , Mycoplasma genitalium , Sexually Transmitted Diseases , Urethritis , Female , Humans , Male , Mycoplasma Infections/epidemiology , Prevalence , Sexually Transmitted Diseases/epidemiology , Tertiary Care Centers , Urethritis/epidemiologyABSTRACT
Objetivos Comprobar la frecuencia de altas no programadas y su relación con la mortalidad hospitalaria tras la estancia en UCI. Diseño Registro prospectivo de los ingresos de 6 años consecutivos. Análisis retrospectivo de la primera admisión de la cohorte de los supervivientes a UCI. Ámbito UCI polivalente de 10 camas en hospital general de segundo nivel con 540 camas. Pacientes Intervenciones: Ninguna.1.521 pacientes con más de 12 horas de estancia, dados de alta vivos y con desenlace hospitalario conocido. Principales variables de interés Se registró el tipo de alta de la unidad, normal o no programada, y se exploró su relación con la mortalidad hospitalaria post-UCI, las tasas de readmisión y la estancia hospitalaria post-UCI. Resultados Hubo 165 altas no programadas (10,8%). La tasa de mortalidad fue del 11,6% (176 pacientes). Los factores relacionados con la mortalidad fueron la limitación del esfuerzo terapéutico (OR=14,02 [4,6-42,6]), las readmisiones (OR=3,46 [1,76-6,78]), las altas no programadas (OR=2,16 [1,06-4,41]), la puntuación de fallos orgánicos al alta de UCI (OR=1,16 [1,01-1,32]) y la edad (OR=1,03 [1,01-1,05]). Las readmisiones y las estancias post-UCI no diferían significativamente entre las altas no programadas y las normales (el 7,3 frente al 8,2%; p=0,68 y 16, 7±16,7 frente a 18,7±21,3 días, respectivamente; p=0,162). Conclusiones Las altas no programadas son frecuentes en nuestro medio y contribuyen significativamente a la mortalidad post-UCI, sin que parezcan afectar a otros resultados de la asistencia a pacientes críticos (AU)
Abstract Objective: To determine the frequency and to evaluate the relationship between prematuredischarge and post-ICU hospital mortality. Design: A prospective registry was made for patients admitted during six consecutive years,performing a retrospective analysis of the data on the first admission of ICU survivors. Setting: A 10-bed general ICU in a 540-bed tertiary-care community hospital. Patients: 1,521 patients with an ICU stay longer than 12 hours, discharged alive to wards withknown hospital outcome. Interventions: None. Main variables: We recorded the patient data, including types of ICU discharge, normal orpremature, and studying their relationship with post-ICU hospital mortality. The types of ICUdischarge were also evaluated versus ICU readmission rate and post-ICU length of stay. Results: There were 165 patients (10.8%) with premature discharge. Mortality rate was11.6% (176 patients). The factors related with mortality were withdrawal and limitation oflife-sustaining treatments (OR=14.02 [4.6-42.6]), readmissions to ICU (OR=3.46 [1.76-6.78]),premature discharge (OR=2.6 [1.06-4.41]), higher organ failure score on discharge from the ICU(OR=1.16 [1.01-1.32]) and age (OR=1.03 [1.01-1.05]). Readmission rates and post-ICU length ofstay were similar among patients with premature and normal discharge (7.3% vs. 8.2%, P=.68and 16.7±16.7 days vs. 18.7±21.3 days, respectively, P=.162). Conclusions: Premature discharges appear to be common in our setting and have a significantimpact on mortality. Types of ICU discharge do not seem to be related with other outcomevariables in the hospital care of critically ill patients (AU)
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Spain/epidemiology , Hospital Mortality , Intensive Care Units , Patient DischargeABSTRACT
OBJECTIVE: To determine the frequency and to evaluate the relationship between premature discharge and post-ICU hospital mortality. DESIGN: A prospective registry was made for patients admitted during six consecutive years, performing a retrospective analysis of the data on the first admission of ICU survivors. SETTING: A 10-bed general ICU in a 540-bed tertiary-care community hospital. PATIENTS: 1,521 patients with an ICU stay longer than 12 hours, discharged alive to wards with known hospital outcome. INTERVENTIONS: None. MAIN VARIABLES: We recorded the patient data, including types of ICU discharge, normal or premature, and studying their relationship with post-ICU hospital mortality. The types of ICU discharge were also evaluated versus ICU readmission rate and post-ICU length of stay. RESULTS: There were 165 patients (10.8%) with premature discharge. Mortality rate was 11.6% (176 patients). The factors related with mortality were withdrawal and limitation of life-sustaining treatments (OR=14.02 [4.6-42.6]), readmissions to ICU (OR=3.46 [1.76-6.78]), premature discharge (OR=2.6 [1.06-4.41]), higher organ failure score on discharge from the ICU (OR=1.16 [1.01-1.32]) and age (OR=1.03 [1.01-1.05]). Readmission rates and post-ICU length of stay were similar among patients with premature and normal discharge (7.3% vs. 8.2%, P=.68 and 16.7±16.7 days vs. 18.7±21.3 days, respectively, P=.162). CONCLUSIONS: Premature discharges appear to be common in our setting and have a significant impact on mortality. Types of ICU discharge do not seem to be related with other outcome variables in the hospital care of critically ill patients.
