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1.
Rofo ; 181(7): 683-90, 2009 Jul.
Article in English | MEDLINE | ID: mdl-19241327

ABSTRACT

PURPOSE: Determination of an adequate scan delay for routine abdominal 64-slice CT examinations with body weight-adapted contrast application. MATERIALS AND METHODS: 57 patients underwent abdominal CT with a 64-slice scanner. The contrast material was adapted to patient body weight. All patients were randomized into five groups with varying scan delay and scan direction (group 1: delay 65 sec; group 2: 75 sec; group 3: 85 sec, craniocaudal; group 4: 85 sec, caudocranial; group 5: 95 sec). Two blinded radiologists evaluated the image quality. CT values (HU) were obtained in different segments of the aorta, inferior vena cava, iliac veins, portal vein, hepatic veins and liver, spleen and pancreas. Statistical analysis was performed using the independent sample t-test and ANOVA test. RESULTS: The diagnostic acceptability of protocols 3 and 4 were rated equally good and significantly/substantially superior to protocol 1 (p = 0.004/0.008) and protocol 5, respectively. Contrast enhancement in the aorta and portal vein peaked at 65 sec. Contrast enhancement in the hepatic and iliac veins peaked at 85 sec independently of the scan direction but was substantially lower at 75 sec. Liver parenchyma enhancement was lowest at 95 sec. CONCLUSION: This data suggests an optimal scan delay for routine abdominal 64-slice CT of 85 sec regardless of scan direction.


Subject(s)
Abdominal Neoplasms/diagnostic imaging , Abdominal Neoplasms/pathology , Body Weight , Contrast Media/administration & dosage , Image Enhancement/methods , Image Processing, Computer-Assisted/methods , Iopamidol/analogs & derivatives , Tomography, Spiral Computed/methods , Abdominal Neoplasms/blood supply , Adult , Aged , Aged, 80 and over , Aortography , Celiac Artery/diagnostic imaging , Celiac Artery/pathology , Dose-Response Relationship, Drug , Double-Blind Method , Drug Administration Schedule , Female , Hepatic Veins/diagnostic imaging , Hepatic Veins/pathology , Humans , Injections, Intravenous , Iopamidol/administration & dosage , Iopamidol/pharmacokinetics , Liver/diagnostic imaging , Liver/pathology , Male , Middle Aged , Neoplasm Staging , Pancreas/diagnostic imaging , Pancreas/pathology , Portal Vein/diagnostic imaging , Portal Vein/pathology , Spleen/diagnostic imaging , Spleen/pathology , Time Factors , Young Adult
2.
Z Orthop Ihre Grenzgeb ; 144(2): 192-8, 2006.
Article in German | MEDLINE | ID: mdl-16625450

ABSTRACT

INTRODUCTION: The anatomically shaped, cementless total hip replacement (THR) (S and G, ESKA Lübeck) has a fully porous coating for secondary osseointegration. The aim of the present study was to analyse the long-term effect of the prosthesis on periprosthetic bone remodelling. METHODS: 137 THR in 117 patients were analysed clinically and radiographically 12.8 years (10-14.9 years) postoperatively. The average age at the last follow-up was 71.8 years (range: 34-87 years). Osteodensitometric DEXA measurements of the periprosthetic bone in comparison to the contralateral non-operated femora were performed. RESULTS: Cumulative survival rates of all implanted THR (n = 231) at 14.9 years were 86.2 % (+/-5.3 %) for the fully porous coated stem and 90.1 % (+/- 8 %) for the cup. Five stem fractures (3.6 %) at the middle part were recorded. The Harris hip score of the non-revised THR at the last follow-up averaged 88.3 (34-100) points. Bony atrophy in the proximal periprosthetic femora in Gruen zones I (16.8 %) and VII (34.6 %) confirmed a proximal stress-shielding. Osteodensitometric analyses demonstrated in comparison to the contralateral femora (BMD 1.3 g/cm (2)) a significantly reduced bone density at the calcar femoris (BMD 0.9 g/cm (2)) (p < 0.001). CONCLUSION: The original goal of a physiological load transfer has not been realised with this fully porous, cementless THR. The anatomic S & G stem will mainly be osseointegrated by distal load transfer.


Subject(s)
Arthroplasty, Replacement, Hip/instrumentation , Arthroplasty, Replacement, Hip/statistics & numerical data , Hip Prosthesis/statistics & numerical data , Metals , Osteolysis/epidemiology , Prosthesis Failure , Absorptiometry, Photon/statistics & numerical data , Adult , Aged , Aged, 80 and over , Disease-Free Survival , Equipment Failure Analysis , Female , Follow-Up Studies , Germany/epidemiology , Humans , Longitudinal Studies , Male , Middle Aged , Osteolysis/diagnostic imaging , Retrospective Studies , Surface Properties , Treatment Outcome
3.
Arch Orthop Trauma Surg ; 126(1): 28-35, 2006 Jan.
Article in English | MEDLINE | ID: mdl-16283343

ABSTRACT

INTRODUCTION: The influence of a spongy metal surface total hip arthroplasty (THA) (S&G, ESKA, Lübeck, Germany) on the clinical, psychometric, and radiograhic long-term results were examined. MATERIAL AND METHODS: An amount of 137 THA with the cementless spongy metal Lübeck hip prosthesis were evaluated long-term, radiographically and clinically, with a mean follow-up time of 12.8 years (range 10.1-14.9 years). The MOS SF-36 was used to assess the health-related quality of life (HRQL). RESULTS: Cumulative survival rates were 90% (+/-8%) for the cups and 86% (+/-5%) for the stems at 14.9 years. Four stems fractured at the middle part (3%) without major trauma. In the remaining patients the clinical results expressed as Harris Hip Score (HHS) averaged 88 (range 34-100). Patients above 60 years undergoing THA had no significant difference in HRQL (MOS SF-36) in comparison to the age-matched healthy population (P>0.05). Patients younger than 60 years had scores lower than normal in the physical function domains (P<0.01), but were comparable in the mental health domains (P>0.05). Radiolucent lines and bone atrophy related to stress shielding by distal fixation were found in the periprosthetic Gruen Zone I (19.8, 16.8%) and VII (10.3, 27.1%) of the proximal femur. DISCUSSION: Whereas the rate of aseptic cup failures of the cementless spongy metal Lübeck hip prosthesis is among the best, the failure rate of the stems is attributable to osteolysis of the proximal femur. The fractures of the stem may be attributed to the combination of the lack of proximal support, the fully porous stem made of a cast cobalt-chrome-molybdenum alloy, and the narrow dimension of the stem core. The long-term results of the spongy metal cup are good, whereas the high loosening and fracture rate of fully coated stem are a source of concern especially with regard to the difficult revision scenario with frequent massive bone loss.


Subject(s)
Arthroplasty, Replacement, Hip/instrumentation , Hip Prosthesis , Internal Fixators , Metals , Osteoarthritis, Hip/surgery , Adult , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/methods , Bone Cements , Female , Femur/diagnostic imaging , Femur/surgery , Follow-Up Studies , Health Status , Humans , Male , Middle Aged , Osseointegration , Osteoarthritis, Hip/diagnostic imaging , Osteoarthritis, Hip/physiopathology , Prosthesis Failure , Quality of Life , Radiography , Severity of Illness Index , Surveys and Questionnaires , Treatment Outcome
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