[Bronchiolitis obliterans organizing pneumonia: survey based on two cases]. / Bronchiolitis obliterans szervülö pneumoniával: áttekintés két eset kapcsán.

Authors offer a survey about an aspect forming a clinical entity called bronchiolitis obliterans organizing pneumonia, by two of their patients' presentation. In Case 1 the process manifested in form of a disseminated, small spotted, diffuse shadow, causing serious resting hypoxia. Diagnosis was supported by histological examination of a substance obtained by small surgical thoracotomy. Five months' therapy of Imuran and altogether 15 months' therapy of Prednisolon resulted in recovery. Second patient's symptoms and the shadow representated in the left upper lung field on chest X-ray, proposed the probability of a tumour. The lesion removed surgically, together with the left upper lobe, proved to be the clinical appearance that constitutes histologically the subject of this paper. Surgery alone resulted in definitive recovery. Disease can be proved on the basis of histological picture and it's important to sunder it primarily from bronchiolitis obliterans as well as from other interstitial pulmonary diseases.

The Clinical Significance of the Primary Malignant Melanoma of the Lower Respiratory Tract and/or Lung Based on the Analysis of Published Case Reports and of Two Patients.

Considering the data and including two patients of the authors, there exist only 18 authentic cases of primary malignant melanoma of the lower respiratory tract and/or the lung. The tumor was localized in the endobronchial space in 7 cases and only once in the trachea. Endobronchial localization, together with the involvement of the surrounding lung tissue, was found in two cases, whereas in 8 patients, the tumor was found exclusively in the lung parenchyma. Successful resection could be performed in 14 of the 18 cases. Survival was influenced primarily by operability, and on actual size and extension. The authors question the role of the obduction in the diagnostic criteria, because most of the survivors, even up to ten years postsurgery were considered primary. Apart from the various imaging methods, diagnostic endoscopy (i.e., bronchoscopy) and the histology of the biopsy material are major aides in the diagnosis of primary character, location, and operability, as well as in the elaboration of the surgical plans, than it is usual in cases of other tumors.

[Primary malignant melanoma of the lung and lower respiratory tract]. / Az alsó légutak és a tüdö primaer malignus melanomája.

After detailed analysis of the international special literature, the authors found--together with their own two patients--only 18 cases, considered primer malignant melanoma of the lower respiratory tract and/or lung. Of the accepted criteria, they dispute the obduction's absolute evidentiary role, because among primer patients there are the most who survives, even a decade. In seven cases tumour was located endobronchially and in one patient in the trachea. It was manifested endobronchially and on the dependent lung-areas, simultaneously in two patients and merely parenchymally, in eight. There was a successful resection in fourteen of 18 cases. Survival was influenced primarily by the operability depending on distension of the tumour. Besides procedures forming opinions, bronchoscopy and histological examinations of bioptatum gained this way play a greater role than usual in determining the tumour's primarity, localisation, operability and type of surgery, respectively. Namely, only operated patients can rely on a long survival.