ABSTRACT
La introducción de la angiografía por tomografía de coherencia óptica (OCT-A) ha generado interés en evaluar las alteraciones vasculares en la cabeza del nervio óptico para el diagnóstico y monitorización del glaucoma. El propósito de este estudio es comparar la perfusión del disco óptico entre sujetos normales y sujetos con glaucoma usando OCT-A para detectar cambios en la perfusión del disco óptico. El sistema OCTA AngioVue examinó 40 ojos de 40 pacientes (20 con glaucoma y 20 controles sanos). La densidad de flujo peripapilar radial total (4,5×4,5mm) se midió en diferentes niveles de segmentación. El estudio demostró que el flujo vascular peripapilar de la OCT-A y la exploración de la cabeza del nervio óptico fue mejor en los ojos normales en comparación con los pacientes con glaucoma. Esta revisión proporciona un resumen exhaustivo de las aplicaciones actuales y potenciales más importantes de OCTA en el glaucoma (AU)
The introduction of optical coherence tomography angiography (OCT-A) has generated interest in evaluating vascular dysfunctions in the optic nerve head for the diagnosis and monitoring of glaucoma. The purpose of this study is to compare perfusion of the optic disc between normal subjects and subjects with glaucoma using OCT-A in order to detect changes in perfusion of the optic disc. Using the OCT-A AngioVue® system, an examination was performed on 40 eyes of 40 patients (20 with glaucoma and 20 healthy controls). Total radial peripapillary flow density (4.5×4.5mm) was measured at different levels of segmentation. The study demonstrated that the peripapillary vascular flow of OCT-A and exploration of the optic nerve head was better in the normal eyes compared to glaucoma patients. This review provides a comprehensive summary of the most important current and potential applications of OCT-A in glaucoma (AU)
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Glaucoma/diagnostic imaging , Optic Nerve/diagnostic imaging , Computed Tomography Angiography , Tomography, Optical Coherence , Case-Control StudiesABSTRACT
The introduction of optical coherence tomography angiography (OCT-A) has generated interest in evaluating vascular dysfunctions in the optic nerve head for the diagnosis and monitoring of glaucoma. The purpose of this study is to compare perfusion of the optic disc between normal subjects and subjects with glaucoma using OCT-A in order to detect changes in perfusion of the optic disc. Using the OCT-A AngioVue® system, an examination was performed on 40 eyes of 40 patients (20 with glaucoma and 20 healthy controls). Total radial peripapillary flow density (4.5×4.5mm) was measured at different levels of segmentation. The study demonstrated that the peripapillary vascular flow of OCT-A and exploration of the optic nerve head was better in the normal eyes compared to glaucoma patients. This review provides a comprehensive summary of the most important current and potential applications of OCT-A in glaucoma.
ABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Tuberculosis, Ocular/diagnostic imaging , Uveitis, Intermediate/diagnostic imaging , Multimodal Imaging , Uveitis, Intermediate/drug therapy , Tuberculosis, Ocular/drug therapy , Adrenal Cortex Hormones/therapeutic useSubject(s)
Fluorescein Angiography , Microscopy, Acoustic , Multimodal Imaging , Tomography, Optical Coherence , Tuberculosis, Ocular/diagnostic imaging , Uveitis, Intermediate/diagnostic imaging , Adult , Female , Humans , Macular Edema/diagnostic imaging , Macular Edema/etiology , Tuberculosis, Ocular/complications , Uveitis, Intermediate/complicationsABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Choroid Diseases/diagnostic imaging , Choroid Diseases/etiology , Choroid/injuries , Rupture/diagnostic imaging , Rupture/etiology , Tomography, Optical Coherence , Computed Tomography AngiographyABSTRACT
CASO CLÍNICO: Mujer de 53 años con agujero macular estadio 2, que recibió como primera opción terapéutica una inyección de ocriplasmina, pero a la que se le tuvo que practicar vitrectomía pars plana por aumento del agujero macular postinyección. La ganancia visual tras la cirugía fue mínima a pesar del cierre del agujero, lo que podría explicarse por la atrofia retiniana externa como consecuencia de los potenciales mecanismos tóxicos asociados a ocriplasmina. Discusión: Son necesarios más estudios para entender el completo impacto de la ocriplasmina en la función visual a largo plazo
CASE REPORT: A 53 year-old woman with a stage 2 macular hole received ocriplasmin injection as a first approach. She subsequently underwent pars plana vitrectomy due to enlargement of the hole post-injection. The visual gain following the surgery was minimal despite closure of the hole. This could be explained by outer retina atrophy as a consequence of potential toxic mechanisms related to ocriplasmin. DISCUSSION: Further studies may be warranted to fully understand the impact of ocriplasmin on long-term visual function
Subject(s)
Humans , Female , Middle Aged , Retinal Diseases/complications , Retinal Perforations/chemically induced , Retinal Perforations/surgery , Vitreous Detachment/drug therapy , Vitrectomy/methods , Fibrinolysin/administration & dosage , Intravitreal Injections , Treatment Failure , Retinal Diseases/chemically induced , Minimally Invasive Surgical Procedures/methods , Visual Acuity , Fibrinolysin/adverse effectsABSTRACT
CASE REPORT: A 53 year-old woman with a stage 2 macular hole received ocriplasmin injection as a first approach. She subsequently underwent pars plana vitrectomy due to enlargement of the hole post-injection. The visual gain following the surgery was minimal despite closure of the hole. This could be explained by outer retina atrophy as a consequence of potential toxic mechanisms related to ocriplasmin. DISCUSSION: Further studies may be warranted to fully understand the impact of ocriplasmin on long-term visual function.
Subject(s)
Fibrinolysin/adverse effects , Peptide Fragments/adverse effects , Retinal Diseases/chemically induced , Female , Fibrinolysin/therapeutic use , Humans , Middle Aged , Peptide Fragments/therapeutic use , Retinal Perforations/drug therapy , Treatment FailureABSTRACT
No disponible
Subject(s)
Humans , Macular Edema/drug therapy , Diabetic Retinopathy/drug therapy , Biological Therapy , 50303 , Bevacizumab/therapeutic use , Ranibizumab/therapeutic use , Intravitreal InjectionsSubject(s)
Bevacizumab/economics , Cost-Benefit Analysis , Diabetic Retinopathy/economics , Macular Edema/economics , Ranibizumab/economics , Recombinant Fusion Proteins/economics , Bevacizumab/therapeutic use , Diabetic Retinopathy/drug therapy , Humans , Macular Edema/drug therapy , Ranibizumab/therapeutic use , Receptors, Vascular Endothelial Growth Factor/therapeutic use , Recombinant Fusion Proteins/therapeutic use , SpainABSTRACT
No disponible
Subject(s)
Female , Humans , Male , Osmolar Concentration , Graft vs Host Disease/complications , Graft vs Host Disease/diagnosis , Xerophthalmia/complications , Ophthalmic Solutions/therapeutic use , Graft vs Host Disease/physiopathology , Graft vs Host Disease , Ophthalmic Solutions , Lubricant Eye Drops/therapeutic useSubject(s)
Dry Eye Syndromes/drug therapy , Graft vs Host Disease/complications , Lubricant Eye Drops/therapeutic use , Dry Eye Syndromes/etiology , Dry Eye Syndromes/physiopathology , Humans , Hypotonic Solutions/therapeutic use , Osmolar Concentration , Surface Properties , Tears/chemistry , Tears/physiology , Tomography, Optical CoherenceABSTRACT
No disponible
Subject(s)
Adult , Humans , Male , Pheochromocytoma/diagnosis , Pheochromocytoma/pathology , Hypertension/complications , Hypertension/diagnosis , Vomiting/diagnosis , Retinal Hemorrhage/complications , Hypertensive Retinopathy/complications , Hypertensive Retinopathy/diagnosis , Pheochromocytoma/complications , Pheochromocytoma , Hypertension/classification , Hypertension/prevention & control , Vomiting/enzymology , Vomiting/metabolism , Retinal Hemorrhage/metabolism , Headache/pathologySubject(s)
Adrenal Gland Neoplasms/complications , Hypertensive Retinopathy/etiology , Pheochromocytoma/complications , Adrenal Gland Neoplasms/diagnosis , Adrenal Gland Neoplasms/diagnostic imaging , Adrenal Gland Neoplasms/surgery , Adrenalectomy , Adult , Emergencies , Headache/etiology , Humans , Hyperhidrosis/etiology , Hypertension, Malignant/etiology , Hypertensive Retinopathy/diagnostic imaging , Magnetic Resonance Imaging , Male , Pheochromocytoma/diagnosis , Pheochromocytoma/diagnostic imaging , Pheochromocytoma/surgery , Remission Induction , Retinal Hemorrhage/etiology , Tomography, Optical CoherenceABSTRACT
No disponible
Subject(s)
Humans , Blepharitis/drug therapy , Ether/therapeutic use , Mites/pathogenicity , Ivermectin/therapeutic useSubject(s)
Acaricides/therapeutic use , Blepharitis/drug therapy , Ether/therapeutic use , Ivermectin/therapeutic use , Mite Infestations/drug therapy , Acaricides/administration & dosage , Acaricides/pharmacology , Administration, Topical , Blepharitis/parasitology , Drug Resistance , Ether/administration & dosage , Humans , Ivermectin/pharmacology , Male , Middle Aged , Mite Infestations/parasitologyABSTRACT
No disponible
Subject(s)
Humans , Corneal Surgery, Laser/methods , Refractive Surgical Procedures/methods , Corneal Diseases/surgerySubject(s)
Corneal Dystrophies, Hereditary/surgery , Corneal Surgery, Laser/methods , Administration, Ophthalmic , Calcinosis/drug therapy , Calcinosis/etiology , Calcinosis/surgery , Chelating Agents/administration & dosage , Chelating Agents/therapeutic use , Combined Modality Therapy , Corneal Dystrophies, Hereditary/etiology , Curettage , Dry Eye Syndromes/drug therapy , Dry Eye Syndromes/etiology , Edetic Acid/administration & dosage , Edetic Acid/therapeutic use , Female , Humans , Injections, Intraocular , Lasers, Excimer/therapeutic use , Lubricant Eye Drops/therapeutic use , Marfan Syndrome/complications , Middle Aged , Visual AcuityABSTRACT
No disponible