Subject(s)
Cataract Extraction , Cataract , Endophthalmitis , Eye Infections, Bacterial , Anti-Bacterial Agents/therapeutic use , Antibiotic Prophylaxis , Chloramphenicol/therapeutic use , Endophthalmitis/epidemiology , Endophthalmitis/etiology , Endophthalmitis/prevention & control , Eye Infections, Bacterial/drug therapy , Eye Infections, Bacterial/epidemiology , Eye Infections, Bacterial/prevention & control , Humans , Ophthalmic Solutions , Postoperative Complications/drug therapy , Postoperative Complications/prevention & control , Retrospective StudiesABSTRACT
PURPOSE: To evaluate the accuracy of 3 new methods for intraocular lens (IOL) power selection (Hill-Radial Basis Function [Hill-RBF] method, FullMonte method, and the Ladas Super Formula) compared with that of the Holladay 1 and Barrett Universal II formulas. SETTING: Ophthalmology Department, Alfred Hospital, Melbourne, Australia. DESIGN: Retrospective case series. METHODS: Patients who had uneventful cataract surgery with insertion of the Acrysof IQ SN60WF IOL over 5 years were included in the study. Data obtained from the electronic medical record and the IOLMaster device were entered into the respective calculators using self-designed computer programs. Using optimized lens constants, the predicted refractive outcome using each of the 5 methods/formulas was calculated and compared with the actual refractive outcome to give the prediction error. Eyes were separated into subgroups based on axial length as follows: short (≤22.0 mm), medium (>22.0 to <24.5 mm), medium-long (≥24.5 to <26.0 mm), and long (≥26.0 mm). RESULTS: The study comprised 3122 eyes of 3122 patients. A statistically significant difference in the mean absolute prediction error (MAE) between the 5 methods for IOL power calculation was found (P < .001), with the Barrett Universal II formula being the most accurate. The Ladas Super Formula had the third lowest MAE, the Hill-RBF the fourth lowest MAE, and the FullMonte the highest MAE of the 5 methods assessed. CONCLUSION: New methods for predicting the postoperative refraction failed to yield more accurate results than current formulas.
Subject(s)
Cataract Extraction , Lens Implantation, Intraocular , Lenses, Intraocular , Humans , Optics and Photonics , Phacoemulsification , Retrospective StudiesABSTRACT
PURPOSE: To assess the accuracy of 7 intraocular lens (IOL) power formulas (Barrett Universal II, Haigis, Hoffer Q, Holladay 1, Holladay 2, SRK/T, and T2) using IOLMaster biometry and optimized lens constants. SETTING: Public hospital ophthalmology department. DESIGN: Retrospective case series. METHODS: Data from patients having uneventful cataract surgery with Acrysof IQ SN60WF IOL implantation over 5 years were obtained from the biometry and patient charts. Optimized lens constants were calculated for each formula and used to determine the predicted refractive outcome for each patient. This was compared with the actual refractive outcome to give the prediction error. Eyes were separated into subgroups based on axial length (AL) as follows: short (≤22.0 mm), medium (>22.0 to <24.5 mm), medium long (≥24.5 to <26.0 mm), and long (≥26.0 mm). RESULTS: The study included 3241 patients. The Barrett Universal II formula had the lowest mean absolute prediction error over the entire AL range (P < .001, all formulas) as well as in the medium (P < .001, all formulas), medium-long (P < .001, except Holladay 1 and T2), and long AL (P < .001, except T2) subgroups. No statistically significant difference was seen between formulas in the short AL subgroup. Overall, the Barrett Universal II formula resulted in the highest percentage of eyes with prediction errors between ±0.25 diopter D, ±0.50 D, and ±1.00 D. CONCLUSION: In eyes with an AL longer than 22.0 mm, the Barrett Universal II formula was a more accurate predictor of actual postoperative refraction than the other formulas. FINANCIAL DISCLOSURE: None of the authors has a financial or proprietary interest in any material or method mentioned.
Subject(s)
Lens Implantation, Intraocular , Lenses, Intraocular , Refraction, Ocular , Biometry , Humans , Models, Theoretical , Optics and Photonics , Phacoemulsification , Reference Values , Retrospective StudiesSubject(s)
Eye Enucleation/psychology , Facial Injuries/diagnostic imaging , Facial Injuries/psychology , Self Mutilation/psychology , Aged , Brain Abscess/complications , Craniotomy/methods , Emergency Treatment , Facial Injuries/complications , Facial Injuries/surgery , Fatal Outcome , Female , Humans , Medication Adherence/psychology , Schizophrenia/complications , Self Mutilation/complications , Self Mutilation/surgery , Soft Tissue Injuries , Tomography Scanners, X-Ray ComputedABSTRACT
PURPOSE: To report a case of a child with near-simultaneous onset of Vogt Koyanagi Harada disease (VKH) and insulin-dependent diabetes mellitus (IDDM). DESIGN: Interventional case report. METHODS: An 11-year-old child with known psoriasis presented with headache and bilateral granulomatous panuveitis. Nine weeks later, he presented with diabetic ketoacidosis and IDDM. Diffuse choroidal depigmentation followed within months. HLA was positive for DRB1*0405. Despite aggressive local and systemic therapy, the ocular disease was complicated by bilateral cataracts, angle closure glaucoma, and choroidal neovascularization. RESULTS: The patient is currently pseudophakic in one eye and aphakic in the other, with best-corrected visual acuity of 6/24 and 6/5, respectively. CONCLUSIONS: VKH may present in children with panuveitis in the setting of other autoimmune disorders. Treating such patients is complicated by the need to minimize systemic corticosteroid use. A combination of local therapy and systemic steroid-sparing agents should be the mainstay of treatment.
