1.
J Indian Med Assoc
; 84(12): 376-8, 1986 Dec.
Article
in English
| MEDLINE
| ID: mdl-3585015
2.
Indian J Med Res
; 83: 360-2, 1986 Apr.
Article
in English
| MEDLINE
| ID: mdl-3721542
3.
Indian J Physiol Pharmacol
; 30(1): 115-7, 1986.
Article
in English
| MEDLINE
| ID: mdl-3818028
4.
Indian J Physiol Pharmacol
; 29(4): 223-6, 1985.
Article
in English
| MEDLINE
| ID: mdl-3842376
ABSTRACT
Ethambutol (20 mg/kg) was administered orally to 10 patients of pulmonary tuberculosis for seven consecutive days at 8 a.m. after over night fast. On 7th day serum levels were measured at 2, 4, 6, 8 and 24 hr intervals and urinary excretion was estimated at 2, 4, 6 and 24 hr following ethambutol administration. Simultaneous administration of isoniazid (300 mg, orally) for next seven days to the same patients significantly raised the serum levels of ethambutol at 4, 6 and 8 hr and the cumulative per cent dose excreted was decreased significantly at 4, 6 and 24 hr. The serum levels and urinary elimination was not significantly different at 2 hr.
Subject(s)
Ethambutol/metabolism , Isoniazid/metabolism , Tuberculosis, Pulmonary/drug therapy , Administration, Oral , Adult , Ethambutol/therapeutic use , Female , Humans , Isoniazid/therapeutic use , Male , Middle Aged , Tuberculosis, Pulmonary/metabolism
5.
J Indian Med Assoc
; 83(1): 30-2, 1985 Jan.
Article
in English
| MEDLINE
| ID: mdl-4008957
6.
Indian J Chest Dis Allied Sci
; 19(3): 131-3, 1977 Jul.
Article
in English
| MEDLINE
| ID: mdl-77253