ABSTRACT
The paper presents the results of clinical studies on the effectiveness of nanohybrid composite Filtek Z550 (3M ESPE) for the restoration of class I cavities.
Subject(s)
Composite Resins/therapeutic use , Dental Caries/therapy , Nanostructures/therapeutic use , Adolescent , Adult , Dental Cements/therapeutic use , Dental Pulp Cavity , Female , Humans , Male , Young AdultSubject(s)
Dental Enamel/drug effects , Dentin/drug effects , Peroxides/pharmacology , Tooth Bleaching , Urea/analogs & derivatives , Bicuspid , Carbamide Peroxide , Dental Enamel/ultrastructure , Dentin/ultrastructure , Drug Combinations , Drug Evaluation, Preclinical , Gels , Humans , Microscopy, Electron, Scanning , Time Factors , Urea/pharmacologyABSTRACT
Activities of glutamic-oxalacetic transaminase, glutamate dehydrogenase, gamma-glutamyl transferase were reduced in unstimulated pooled saliva of 15-year-old adolescents with endemic fluorosis, vs. those without fluorosis. This point to reduced production of glutamate which is indispensable for bacterial growth. The activity of acid phosphatase in pooled stimulated with 1% pilocarpin saliva of rats fed a water ration with 5 and 20 mg/liter fluorine in comparison with control rats fed water with fluorine concentration of 0.21 mg/liter. Noteworthy that alkaline phosphatase activity was virtually unchanged at fluorine concentrations 5 and 20 mg/liter in the water. The significance of the results as far as it regards the pathogenesis of caries and fluorosis is discussed.