1.
Am J Med
; 126(5): e1-2, 2013 May.
Article
in English
| MEDLINE
| ID: mdl-23490059
2.
Int J Gastrointest Cancer
; 35(3): 211-6, 2005.
Article
in English
| MEDLINE
| ID: mdl-16110123
ABSTRACT
Gastrinomas of the stomach are extremely rare endocrine tumors producing Zollinger-Ellison syndrome. We report here the case of a patient with gastrinoma of the stomach who presented regional and hepatic metastases at the time of diagnosis. The endocrine tumor was discovered incidentally 8 yr after the onset of symptoms related to peptic ulcer, which responded to medical treatment with a proton pump inhibitor. Surgery did not cure the patient, as demonstrated by provocative tests showing serum gastrin responses indicative of residual disease. A long-term treatment with the somatostatin analog lanreotide induced a biochemical response and was associated with a substantially stable disease.