ABSTRACT
Surgical resection of pulmonary metastasis is appropriate provided the general principals of oncological surgery are followed. Complete excision of the metastatic tumor is associated with long-term survival and low perioperative mortality. We present 2 cases of single pulmonary metastasis from osteosarcoma with cardiac involvement. In both cases, complete excision required left pneumonectomy by sternotomy with extracorporeal circulation. The outcomes were favorable, no perioperative complications were reported, and the patients remained free of disease at 14 and 17 months after surgery. In conclusion, we believe that the cases presented confirm that extended pneumonectomy with extracorporeal circulation if necessary is a valid approach for complete resection of pulmonary metastasis.
Subject(s)
Bronchial Neoplasms/secondary , Bronchial Neoplasms/surgery , Extracorporeal Circulation , Lung Neoplasms/secondary , Lung Neoplasms/surgery , Osteosarcoma/secondary , Osteosarcoma/surgery , Pneumonectomy/methods , Adult , Antineoplastic Agents/therapeutic use , Arm , Bronchial Neoplasms/diagnostic imaging , Chemotherapy, Adjuvant , Combined Modality Therapy , Femoral Neoplasms/drug therapy , Femoral Neoplasms/pathology , Femoral Neoplasms/surgery , Heart Atria/pathology , Heart Atria/surgery , Humans , Lung Neoplasms/diagnostic imaging , Male , Osteosarcoma/diagnostic imaging , Osteosarcoma/drug therapy , Pericardiectomy/methods , Pericardium/pathology , Pericardium/surgery , Pleura/pathology , Pleura/surgery , Pulmonary Veins/pathology , Pulmonary Veins/surgery , Sarcoma/pathology , Sarcoma/radiotherapy , Sarcoma/surgery , Thoracic Wall/pathology , Thoracic Wall/surgery , Tomography, X-Ray ComputedABSTRACT
La resección quirúrgica de las metástasis pulmonares es un tratamiento aceptado si se mantienen los principios generales de la cirugía oncológica, y la exéresis completa de las metástasis se asocia a una supervivencia a largo plazo y una mortalidad perioperatoría baja. Presentamos 2 casos de metástasis pulmonar única de osteosarcoma con infiltración cardíaca, que requirió para su exéresis completa neumonectomía izquierda por esternotomía, con utilización de circulación extracorpórea. El resultado fue favorable, sin que hubiera complicaciones perioperatorias y los pacientes permanecen indemnes a los 14 y 17 meses de la intervención quirúrgica. En conclusión, consideramos que en casos seleccionados la neumonectomía ampliada, con utilización de circulación extracorpórea si se precisa, para poder realizar la exéresis completa de metástasis pulmonares es un procedimiento válido
Surgical resection of pulmonary metastasis is appropriate provided the general principals of oncological surgery are followed. Complete excision of the metastatic tumor is associated with long-term survival and low perioperative mortality. We present 2 cases of single pulmonary metastasis from osteosarcoma with cardiac involvement. In both cases, complete excision required left pneumonectomy by sternotomy with extracorporeal circulation. The outcomes were favorable, no perioperative complications were reported, and the patients remained free of disease at 14 and 17 months after surgery. In conclusion, we believe that the cases presented confirm that extended pneumonectomy with extracorporeal circulation if necessary is a valid approach for complete resection of pulmonary metastasis
Subject(s)
Humans , Pneumonectomy/methods , Lung Neoplasms/surgery , Extracorporeal Circulation , Osteosarcoma/surgery , Cardiopulmonary Bypass , Postoperative Complications/epidemiology , Neoplasm Metastasis/pathology , Lung Neoplasms/secondaryABSTRACT
In 10%-15% of patients, myasthenia gravis is associated with thymoma. Because of its site, this tumour can have an un-noticed clinical history over a considerable time and be diagnosed when adjacent structures such as mediastinal vessels, heart or trachea become infiltrated. We present a patient with thymoma and infiltration of the superior vena cava, and which represents an incipient vena cava syndrome. The surgical treatment consisted of complete resection of the tumour including partial replacement of the vena cava with a pericardial patch. The surgery was complemented with radiotherapy.
Subject(s)
Thymoma/surgery , Thymus Neoplasms/surgery , Vascular Neoplasms/surgery , Vena Cava, Superior , Aged , Humans , Male , Neoplasm Invasiveness , Surgical Procedures, Operative/methods , Thymoma/pathology , Thymus Neoplasms/pathology , Vascular Neoplasms/pathologyABSTRACT
No disponible
In 10%-15% of patients, myasthenia gravis is associated with thymoma. Because of its site, this tumour can have an un-noticed clinical history over a considerable time and be diagnosed when adjacent structures such as mediastinal vessels, heart or trachea become infiltrated. We present a patient with thymoma and infiltration of the superior vena cava, and which represents an incipient vena cava syndrome. The surgical treatment consisted of complete resection of the tumour including partial replacement of the vena cava with a pericardial patch. The surgery was complemented with radiotherapy