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Braz J Infect Dis ; 28(2): 103742, 2024.
Article in English | MEDLINE | ID: mdl-38670166

ABSTRACT

A substantial number of zoonotic diseases are caused by viral pathogens, representing a significant menace to public health, particularly to susceptible populations, such as pregnant women, the elderly, and immunocompromised individuals. Individuals who have undergone solid organ transplantation frequently experience immunosuppression, to prevent organ rejection, and, thus are more prone to opportunistic infections. Furthermore, the reactivation of dormant viruses can threaten transplant recipients and organ viability. This mini-review examines the up-to-date literature covering potential zoonotic and organ rejection-relevant viruses in solid organ transplant recipients. A comprehensive list of viruses with zoonotic potential is highlighted and the most important clinical outcomes in patients undergoing transplantation are described. Moreover, this mini-review calls attention to complex multifactorial events predisposing viral coinfections and the need for continuous health surveillance and research to understand better viral pathogens' transmission and pathophysiology dynamics in transplanted individuals.


Subject(s)
Immunocompromised Host , Organ Transplantation , Transplant Recipients , Humans , Organ Transplantation/adverse effects , Animals , Virus Diseases/transmission , Virus Diseases/virology , Disease Susceptibility , Zoonoses/transmission , Zoonoses/virology , Viral Zoonoses/transmission , Viral Zoonoses/virology , Risk Factors
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