ABSTRACT
CASO CLÍNICO: Presentamos a un paciente de 77 años, con un cuadro de necrosis retiniana aguda con afectación bilateral; la reacción en cadena de la polimerasa (PCR) de la muestra de humor acuoso fue positiva al virus de varicela zóster. En su evolución desarrolla vasculitis de Kyrieleis al mes de inicio del tratamiento y con el análisis por PCR negativo. DISCUSIÓN: La PCR es un método rápido, con una sensibilidad y especificidad del 97%. La actuación debe ser urgente por la rapidez de la progresión. El famciclovir oral es buena alternativa por su mejor biodisponibilidad
CASE REPORT: The case is reported of acute retinal necrosis with bilateral involvement due to Varicella Zoster virus in a 77 year-old man. Polymerase chain reaction (PCR) of aqueous humor was positive for Varicella Zoster virus (VZV). He developed a Kyrieleis vasculitis a month after the starting treatment, when the PCR analysis was negative. DISCUSSION: PCR is a quick and safe technique, with a high sensitivity and specificity of 97%, useful to diagnose and monitor the viral activity. The intervention must be urgent, due to the dramatically rapid evolution. Oral famciclovir oral is good alternative owing to its bioavailability
Subject(s)
Adult , Humans , Male , Retinal Necrosis Syndrome, Acute/metabolism , Retinal Necrosis Syndrome, Acute/pathology , Herpes Zoster/pathology , Retinitis/genetics , Vasculitis/diagnosis , Polymerase Chain Reaction/methods , Retinal Necrosis Syndrome, Acute/congenital , Retinal Necrosis Syndrome, Acute/genetics , Herpes Zoster/diagnosis , Retinitis/metabolism , Vasculitis/complications , Polymerase Chain ReactionABSTRACT
CASE REPORT: The case is reported of acute retinal necrosis with bilateral involvement due to Varicella Zoster virus in a 77 year-old man. Polymerase chain reaction (PCR) of aqueous humor was positive for Varicella Zoster virus (VZV). He developed a Kyrieleis' vasculitis a month after the starting treatment, when the PCR analysis was negative. DISCUSSION: PCR is a quick and safe technique, with a high sensitivity and specificity of 97%, useful to diagnose and monitor the viral activity. The intervention must be urgent, due to the dramatically rapid evolution. Oral famciclovir oral is good alternative owing to its bioavailability.
Subject(s)
Herpes Zoster Ophthalmicus/complications , Retinal Necrosis Syndrome, Acute/etiology , Aged , Aqueous Humor/virology , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/immunology , Herpesvirus 3, Human/genetics , Herpesvirus 3, Human/isolation & purification , Humans , Immunocompromised Host , Male , Polymerase Chain Reaction , Prostatic Neoplasms/complications , Prostatic Neoplasms/immunology , Retinal Vasculitis/etiology , Slit LampABSTRACT
Caso clínico: Mujer de 25 años de edad que refería una tumoración no dolorosa amarillenta en el ojo derecho. Su agudeza visual era de la unidad. En la exploración en lámpara de hendidura se observa una masa amarilla-anaranjada localizada en el limbo superior del ojo derecho. No se observaron otras anormalidades. Discusión: Se realizó una escisión quirúrgica de la lesión y se remitió a anatomía patológica para su examen. La lesión granulomatosa mostraba células de Touton. Este hecho sugiere de forma importante el diagnóstico de xantogranuloma juvenil (JXG). La afectación ocular ocurre en el 10% de los casos de JXG (AU)
Case report: A 25-year-old woman noticed a painless yellow-orange mass on her right eye. Her visual acuity was 20/20 in both eyes, and a slit-lamp examination showed a yellow-orange mass located at the superior limbus of the right eye. No other ocular abnormalities were observed. Discussion: Surgical excision was carried out and the lesion was sent for histological examination. This showed a granulomatous lesion, rich in Touton-type giant cells, features that are strongly suggestive of juvenile xanthogranuloma (JXG). Ocular involvement occurs in 10% of cases of JXG (AU)
Subject(s)
Humans , Female , Adult , Xanthogranuloma, Juvenile/surgery , Limbus Corneae/pathology , Diagnosis, Differential , Histiocytosis, Non-Langerhans-Cell/complicationsABSTRACT
CASE REPORT: A 25-year-old woman noticed a painless yellow-orange mass on her right eye. Her visual acuity was 20/20 in both eyes, and a slit-lamp examination showed a yellow-orange mass located at the superior limbus of the right eye. No other ocular abnormalities were observed. DISCUSSION: Surgical excision was carried out and the lesion was sent for histological examination. This showed a granulomatous lesion, rich in Touton-type giant cells, features that are strongly suggestive of juvenile xanthogranuloma (JXG). Ocular involvement occurs in 10% of cases of JXG.
Subject(s)
Limbus Corneae/pathology , Xanthogranuloma, Juvenile/diagnosis , Adult , Age of Onset , Diagnosis, Differential , Female , Giant Cells/pathology , Histiocytes/pathology , Humans , Limbus Corneae/surgery , Xanthogranuloma, Juvenile/epidemiology , Xanthogranuloma, Juvenile/pathology , Xanthogranuloma, Juvenile/surgeryABSTRACT
Caso clínico: Presentamos el caso de un niño de 10 años con una distrofia macular viteliforme bilateral, en progresión, y el padre con estadios finales en ambos ojos; se estudia la evolución con la tomografía óptica de coherencia. Discusión: La tomografía óptica de coherencia es una herramienta útil y no invasiva, que permite complementar el diagnóstico y el seguimiento de los pacientes, aportando datos morfológicos de la lesión así como cambios secundarios en la retina adyacente. Demuestra la localización del material amarillento depositado bajo la retina sensorial
Case report: We report the case of a 10-year-old boy with a progressive bilateral vitelliform macular dystrophy, and his father with terminal stage disease in both eyes; we studied the development and progression of this condition with optical coherence tomography. Discussion: Optical coherence tomography is a useful noninvasive tool that complements other diagnostic modalities and improves the follow up assessment. It provides additional information on the morphology of the lesion as well as identifying secondary changes in the adjacent retina. It also demonstrates the location of any yellowish material under the sensory retina (Arch Soc Esp Oftalmol 2008; 83: 501-504)
Subject(s)
Humans , Male , Child , Tomography, Optical Coherence/methods , Muscular Dystrophies/complications , Pigment Epithelium of Eye/pathology , Tomography, Optical Coherence/trends , Tomography, Optical Coherence , Fibrosis/pathologyABSTRACT
CASE REPORT: We report the case of a 10-year-old boy with a progressive bilateral vitelliform macular dystrophy, and his father with terminal stage disease in both eyes; we studied the development and progression of this condition with optical coherence tomography. DISCUSSION: Optical coherence tomography is a useful noninvasive tool that complements other diagnostic modalities and improves the follow up assessment. It provides additional information on the morphology of the lesion as well as identifying secondary changes in the adjacent retina. It also demonstrates the location of any yellowish material under the sensory retina.
