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1.
Cardiovasc Intervent Radiol ; 41(4): 670, 2018 04.
Article in English | MEDLINE | ID: mdl-29380003

ABSTRACT

The published article has an error in the first name initial of one of the authors. "M. Justinger" should be "C. Justinger" as shown in this erratum.

2.
Cardiovasc Intervent Radiol ; 41(5): 744-752, 2018 May.
Article in English | MEDLINE | ID: mdl-29344713

ABSTRACT

INTRODUCTION: To investigate prognostic factors in unresectable intrahepatic cholangiocarcinoma (ICC) therapy-naïve patients after yttrium-90 (Y-90) radioembolization (RE) therapy. MATERIALS AND METHODS: Between 2005 and 2016, 21 patients with ICC were treated with Y-90 RE only and their survival data were analyzed. Patients were stratified and response was assessed by the Response Evaluation Criteria in Solid Tumors (RECIST) criteria. RESULT: The overall median survival was 15 months. Survival was significantly (p = 0.009) prolonged in patients with tumor burden of ≤ 25% (n = 8, OS 37.5 months) versus those with a tumor burden of 25-50% (n = 13, OS 15 months). The other variables: tumor morphology (infiltrative vs. peripheral), tumor distribution (solitary vs. multifocal), lobes involved (unilobar vs. bilobar), FDG PET status (FDG avid vs. non-avid), RE treatment sessions (1 session vs. 2 sessions), metastases (metastasis vs. no metastasis) and RECIST criteria, had no significant impact on survival. CONCLUSION: Tumor burden represents a key prognostic factor of survival in therapy-naïve patients with unresectable ICC treated with Y-90 RE therapy only.


Subject(s)
Bile Duct Neoplasms/radiotherapy , Brachytherapy/methods , Cholangiocarcinoma/radiotherapy , Yttrium Radioisotopes/therapeutic use , Aged , Bile Duct Neoplasms/diagnostic imaging , Bile Ducts, Intrahepatic/diagnostic imaging , Cholangiocarcinoma/diagnostic imaging , Female , Humans , Male , Positron Emission Tomography Computed Tomography , Prognosis , Retrospective Studies , Survival Analysis , Treatment Outcome
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