ABSTRACT
OBJECTIVE: To evaluate the safety and efficacy of contact transcleral ciliary body photodynamic treatment (CB-PDT) with verteporfin in human eyes. DESIGN: Prospective interventional case series. PARTICIPANTS: Five glaucomatous blind eyes of 5 patients. METHODS: Verteporfin (6 mg/m(2)) was infused in bolus and then the ciliary body was irradiated transclerally with a fibre optic device. Twelve spots were placed 360° and 0.5 mm behind the sclerocorneal limbus. Laser power was 80 mW and irradiation time was 3 minutes. RESULTS: The average intraocular pressure reduction was 30% after the first month and remained below pre-treatment levels throughout a 3-month follow-up. No serious adverse events were reported. CONCLUSIONS: CB-PDT for refractory glaucoma was safe and efficient in human eyes; larger studies are required to evaluate its possible clinical role.
Subject(s)
Ciliary Body/drug effects , Glaucoma, Neovascular/drug therapy , Photochemotherapy , Photosensitizing Agents/therapeutic use , Porphyrins/therapeutic use , Aged , Aged, 80 and over , Feasibility Studies , Female , Follow-Up Studies , Humans , Intraocular Pressure , Laser Therapy , Lasers , Male , Middle Aged , Prospective Studies , Sclera , VerteporfinABSTRACT
We present a case of central retinal vein occlusion after an combined phacotrabeculectomy in a patient with advanced open angle glaucoma. Possible pathogenetic mechanisms for this complication are discussed.
Subject(s)
Glaucoma, Open-Angle/surgery , Phacoemulsification/adverse effects , Postoperative Complications/etiology , Retinal Vein Occlusion/etiology , Trabeculectomy/adverse effects , Aged , Female , Humans , Visual AcuityABSTRACT
PURPOSE: To compare the proportions of school children with myopia and impaired visual acuity in Greece and Bulgaria. METHODS: A sample of 898 children, aged 10-15 years, was selected from two primary and two secondary schools in a Greek city (Heraklion), and one primary and secondary school in a Bulgarian city (Stara Zagora). Five hundred and eighty eight children were Greek (65.5%, mean age 12.5 +/- 0.08 years) and 310 Bulgarian (34.5%, age 12.4 +/- 0.07 years). VA was assessed with the habitual refractive correction. Refractive error was measured in the absence of cycloplegia using an auto-refractor. RESULTS: The percentage of children, tested with their habitual refractive correction, with decimal VA <0.5 in at least one eye was 11.7% (95% CI 9.1-14.3%) for Greek and 5.2% (95% CI 2.7-7.6%) for Bulgarian pupils. The percentage of myopic children also differed between the two countries with the proportion with myopic refractive error Subject(s)
Astigmatism/physiopathology
, Myopia/physiopathology
, Vision Disorders/physiopathology
, Visual Acuity/physiology
, Adolescent
, Age Factors
, Astigmatism/epidemiology
, Bulgaria/epidemiology
, Child
, Female
, Greece/epidemiology
, Humans
, Male
, Myopia/epidemiology
, Statistics as Topic
, Vision Disorders/epidemiology