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2.
Open Forum Infect Dis ; 7(11): ofaa492, 2020 Nov.
Article in English | MEDLINE | ID: mdl-33244479

ABSTRACT

We performed whole-genome sequencing of Vibrio cholerae O1 isolates from Laos, Thailand, and Vietnam, where cholera outbreaks occurred, to determine their genetic lineages. Core genome phylogenetic analysis revealed that the isolates located in same lineage without regional clusters, which suggests that closely related strains circulated in Southeast Asia.

3.
Emerg Infect Dis ; 17(11): 2060-2, 2011 Nov.
Article in English | MEDLINE | ID: mdl-22099098

ABSTRACT

A cholera outbreak in Laos in July 2010 involved 237 cases, including 4 deaths. Molecular subtyping indicated relatedness between the Vibrio cholerae isolates in this and in a 2007 outbreak, uncovering a clonal group of V. cholerae circulating in the Mekong basin. Our finding suggests the subtyping methods will affect this relatedness.


Subject(s)
Cholera/epidemiology , Cholera/virology , Disease Outbreaks , Vibrio cholerae O1/classification , Electrophoresis, Gel, Pulsed-Field , Humans , Laos/epidemiology , Molecular Typing/methods , Tandem Repeat Sequences/genetics , Vibrio cholerae O1/genetics , Vibrio cholerae O1/isolation & purification
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