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Clin Chem Lab Med ; 46(9): 1211-9, 2008.
Article in English | MEDLINE | ID: mdl-18681834

ABSTRACT

A new graphical approach for analysis of measurement system comparison studies is proposed. Unlike the established linear regression and Bland-Altman analysis, it does not depend on the assumption of a linear relationship. We review the established analysis approaches and propose a difference plot with non-parametric regression as an adequate tool to describe the relationship between two measurement systems. Along with pre-defined level-dependent acceptance limits, this approach may provide evidence for metrological equivalence between two measurement systems. Several data examples are given to illustrate this approach.


Subject(s)
Regression Analysis , Research Design , Glycated Hemoglobin/analysis , Humans , Immunoglobulin A/analysis , Linear Models
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