Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 51
Filter
1.
Opt Express ; 32(6): 10119-10129, 2024 Mar 11.
Article in English | MEDLINE | ID: mdl-38571231

ABSTRACT

Current imaging spectrometers with conventional optical elements face major challenges in achieving a large field of view (FOV), broadband and compact structure simultaneously. In this paper, a compact freeform-surface-based Offner imaging spectrometer with both a long-slit and a broadband (CISLS) is proposed. To keep a long slit and an anastigmatic imaging, the slit off-axis amount of the initial system is within a specific range theoretically. While to achieve a compact structure, the slit off-axis amount should be away from the specific range and as small as possible. Based on the vector aberration theory and the analytical study, Zernike polynomial terms Z5 and Z6 introduce the astigmatism independent of FOV. They are utilized to well balance the astigmatism when the slit off-axis amount is away from the specific range, helping a miniaturization of the system. Other Zernike polynomial terms below the eighth order introduce the astigmatism related to FOV. They contribute to balancing the astigmatism that produced with the increasing of the FOV, thus achieving a wide FOV. The design results show that the proposed CISLS with a high spectral resolution of 2.7 nm achieves a long slit of 30 mm in length but a small size of only 60 mm × 64 mm × 90 mm in volume under a broadband from 400 nm to 1000 nm.

2.
JAMA Netw Open ; 7(4): e248732, 2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38687480

ABSTRACT

Importance: Individuals with dialysis-dependent kidney failure have numerous risk factors for medication-related adverse events, including receipt of care by multiple clinicians and initiation of some QT-prolonging medications with known risk of torsades de pointes (TdP), which is associated with higher risk of sudden cardiac death. Little is known about the prescription and dispensation patterns of QT-prolonging medications among people receiving dialysis, hindering efforts to reduce drug-related harm from these and other medications in this high-risk population. Objective: To examine prescription and dispensation patterns of QT-prolonging medications with known TdP risk and selected interacting medications prescribed to individuals receiving hemodialysis. Design, Setting, and Participants: This cross-sectional study included patients 60 years or older who were enrolled in Medicare Parts A, B, and D receiving in-center hemodialysis from January 1 to December 31, 2019. Analyses were conducted from October 20, 2022, to June 16, 2023. Exposures: New-user prescriptions for the 7 most frequently filled QT-prolonging medications characterized by the timing of the new prescription relative to acute care encounters, the type of prescribing clinician and pharmacy that dispensed the medication, and concomitant use of selected medications known to interact with the 7 most frequently filled QT-prolonging medications with known TdP risk. Main Outcomes and Measures: The main outcomes were the frequencies of the most commonly filled and new-use episodes of QT-prolonging medications; the timing of medication fills relative to acute care events; prescribers and dispensing pharmacy characteristics for new use of medications; and the frequency and types of new-use episodes with concurrent use of potentially interacting medications. Results: Of 20 761 individuals receiving hemodialysis in 2019 (mean [SD] age, 74 [7] years; 51.1% male), 10 992 (52.9%) filled a study drug prescription. Approximately 80% (from 78.6% for odansetron to 93.9% for escitalopram) of study drug new-use prescriptions occurred outside of an acute care event. Between 36.8% and 61.0% of individual prescriptions originated from general medicine clinicians. Between 16.4% and 26.2% of these prescriptions occurred with the use of another QT-prolonging medication. Most potentially interacting drugs were prescribed by different clinicians (46.3%-65.5%). Conclusions and Relevance: In this cross-sectional study, QT-prolonging medications for individuals with dialysis-dependent kidney failure were commonly prescribed by nonnephrology clinicians and from nonacute settings. Prescriptions for potentially interacting medications often originated from different prescribers. Strategies aimed at minimizing high-risk medication-prescribing practices in the population undergoing dialysis are needed.


Subject(s)
Renal Dialysis , Humans , Male , Cross-Sectional Studies , Female , Aged , Middle Aged , United States , Torsades de Pointes/chemically induced , Long QT Syndrome/chemically induced , Aged, 80 and over , Drug Prescriptions/statistics & numerical data , Kidney Failure, Chronic/therapy
3.
Appl Opt ; 63(6): 1577-1582, 2024 Feb 20.
Article in English | MEDLINE | ID: mdl-38437371

ABSTRACT

Current imaging spectrometers are developed towards a large field of view (FOV) as well as high resolution to obtain more spatial and spectral information. However, imaging spectrometers with a large FOV and high resolution produce a huge image data cube, which increases the difficulty of spectral data acquisition and processing. In practical applications, it is more reasonable and helpful to identify different targets within a large FOV with different spectral resolutions. In this paper, a compact multi-spectral-resolution Wynne-Offner imaging spectrometer with a long slit is proposed by introducing a special diffraction grating with multi-groove densities at different areas. With the increasing of the groove density and the slit length, the astigmatism of the Wynne-Offner imaging spectrometer increases sharply. Therefore, the relationships between the astigmatism and both the groove density and slit length are studied. Moreover, a holographic grating is introduced. The holographic aberrations produced are utilized to balance the residual astigmatism of the imaging spectrometer. The design results show that the system is only 60m m×115m m×103m m in volume but achieves both a long slit of 20 mm in length and a waveband from 400 nm to 760 nm with three kinds of spectral resolutions of 2 nm, 1 nm, and 0.5 nm. The designed compact multi-spectral-resolution Wynne-Offner imaging spectrometer can be widely applied in the fields of crop classification and pest detection, which require both a large FOV and multiple spectral resolutions.

4.
Opt Express ; 31(25): 41595-41610, 2023 Dec 04.
Article in English | MEDLINE | ID: mdl-38087554

ABSTRACT

In measurements based on phase-shifting fringe pattern analysis, residual ripple-like artifacts often appear due to the co-influence of several error sources, e.g., phase-shifting errors, temporal intensity fluctuations and high-order fringe harmonics, when existing algorithms are adopted to retrieve phase using limited number of fringe patterns. To overcome this issue, a general phase-shifting algorithm for hybrid errors suppression by variable-frequency fringes is proposed in this paper for what we believe to be the first time. A corresponding fringe model is deduced to represent real patterns more accurately under the co-influence of these error factors. Variable-frequency fringes are introduced to provide a least and sufficient system of equations, while a least-squares iterative technique with a grouped step-by-step strategy is adopted for stable calculating a larger number of desired parameters in the constructed model. For the phase jump problem caused by non-full rank matrices at certain sampling points, a regularization combined with constraints between coefficients of high-order fringe harmonics is further proposed for identification and processing. Simulations and experimental results have shown that compared with the prior techniques, the accuracies of the proposed algorithm have been significantly enhanced at least 2.1 (simulations) and 1.5 (experiments) times respectively using bi-frequency equal three-step as an example in the study.

5.
Appl Opt ; 62(29): 7766-7772, 2023 Oct 10.
Article in English | MEDLINE | ID: mdl-37855485

ABSTRACT

We report a metasurface cutoff perfect absorber (MCPA) in the solar energy wavelength band based on the double Mie resonances generated from the silicon and gallium arsenide nanoring arrays grown on the Al layer in the solar energy wavelengths. A high average absorption of 0.910 in the absorption band and almost eliminated absorption in the nonabsorption band are realized within only 120 nm thick structures. The MCPA is of a sharp cutoff between the absorption and nonabsorption band, whose extinction ratio, extinction difference, and cutoff slope are 9.4 dB, 0.8, and 0.0019n m -1, respectively. The proposed MCPA suggests an efficient way to design a solar thermal absorber, which is of great importance in renewable energy, such as for solar thermal applications.

6.
Appl Opt ; 62(22): 5991-5998, 2023 Aug 01.
Article in English | MEDLINE | ID: mdl-37706953

ABSTRACT

Wide spectrum and miniaturization are the main challenges in the imaging spectrometer design. In this paper, we propose an ultra-compact dual band imaging spectrometer (CDBIS) with cemented freeform prisms, which works at both the visible-near-infrared (VNIR) from 400 nm to 1000 nm and the shortwave-infrared (SWIR) from 1000 nm to 1700 nm. The imaging spectrometer is only composed of three cemented prisms, a primary prism and two triangular prisms. And a freeform surface characterized by the Zernike polynomial is introduced in each prism. The CDBIS is dispersed by a diffraction grating, which is designed on the second surface of the primary prism. Based on vector aberration theory (VAT), the relationship among the astigmatism generated by the introduced freeform surfaces, the wavelength, and the field of view is studied. Accordingly, a wideband is realized by introducing the freeform surfaces after the diffraction grating. Furthermore, through optimizing the coefficients of Zernike polynomial terms, residual astigmatism at different wavelengths is well balanced. An imaging spectrometer with a volume of only 100c m 3 is obtained, with a spectral resolution of 1.45 nm at VNIR and 2.40 nm at SWIR, respectively. It has a huge potential for broadband space exploration.

7.
Appl Opt ; 62(17): 4456-4464, 2023 Jun 10.
Article in English | MEDLINE | ID: mdl-37707137

ABSTRACT

A snapshot imaging spectrometer is a powerful tool for dynamic target tracking and real-time recognition compared with a scanning imaging spectrometer. However, all the current snapshot spectral imaging techniques suffer from a major trade-off between the spatial and spectral resolutions. In this paper, an integral field snapshot imaging spectrometer (TIF-SIS) with a continuously tunable spatial-spectral resolution and light throughput is proposed and demonstrated. The proposed TIF-SIS is formed by a fore optics, a lenslet array, and a collimated dispersive subsystem. Theoretical analyses indicate that the spatial-spectral resolution and light throughput of the system can be continuously tuned through adjusting the F number of the fore optics, the rotation angle of the lenslet array, or the focal length of the collimating lens. Analytical relationships between the spatial and spectral resolutions and the first-order parameters of the system with different geometric arrangements of the lenslet unit are obtained. An experimental TIF-SIS consisting of a self-fabricated lenslet array with a pixelated scale of 100×100 and a fill factor of 0.716 is built. The experimental results show that the spectral resolution of the system can be steadily improved from 4.17 to 0.82 nm with a data cube (N x×N y×N λ) continuously tuned from 35×35×36 to 40×40×183 in the visible wavelength range from 500 to 650 nm, which is consistent with the theoretical prediction. The proposed method for real-time tuning of the spatial-spectral resolution and light throughput opens new possibilities for broader applications, especially for recognition of things with weak spectral signature and biomedical investigations where a high light throughput and tunable resolution are needed.

8.
Appl Opt ; 62(21): 5830-5838, 2023 Jul 20.
Article in English | MEDLINE | ID: mdl-37707203

ABSTRACT

The comprehensive analysis of dynamic targets brings about the demand for capturing spatial and spectral dimensions of visual information instantaneously, which leads to the emergence of snapshot spectral imaging technologies. While current snapshot systems face major challenges in the development of wide working band range as well as high resolution, our novel dual-channel snapshot imaging spectrometer (DSIS), to the best of our knowlledge, demonstrates the capability to achieve both wide spectrum and high resolution in a compact structure. By dint of the interaction between the working band range and field of view (FOV), reasonable limits on FOV are set to avoid spectral overlap. Further, we develop a dual-channel imaging method specifically for DSIS to separate the whole spectral range into two parts, alleviating the spectral overlap on each image surface, improving the tolerance of the system for a wider working band range, and breaking through structural constraints. In addition, an optimal FOV perpendicular to the dispersion direction is determined by the trade-off between FOV and astigmatism. DSIS enables the acquisition of 53×11 spatial elements with up to 250 spectral channels in a wide spectrum from 400 to 795 nm. The theoretical study and optimal design of DSIS are further evaluated through the simulation experiments of spectral imaging.

9.
Nano Lett ; 23(16): 7584-7592, 2023 Aug 23.
Article in English | MEDLINE | ID: mdl-37539848

ABSTRACT

Optical bound states in the continuum (BICs) offer strong interactions with quantum emitters and have been extensively studied for manipulating spontaneous emission, lasing, and polariton Bose-Einstein condensation. However, the out-coupling efficiency of quasi-BIC emission, crucial for practical light-emitting devices, has received less attention. Here, we report an adaptable approach for enhancing quasi-BIC emission from a resonant monocrystalline silicon (c-Si) metasurface through lattice and multipolar engineering. We identify dual-BICs originating from electric quadrupoles (EQ) and out-of-plane magnetic dipoles, with EQ quasi-BICs exhibiting concentrated near-fields near the c-Si nanodisks. The enhanced fractional radiative local density of states of EQ quasi-BICs overlaps spatially with the emitters, promoting efficient out-coupling. Furthermore, coupling the EQ quasi-BICs with Rayleigh anomalies enhances directional emission intensity, and we observe inherent opposite topological charges in the multipolarly controlled dual-BICs. These findings provide valuable insights for developing efficient nanophotonic devices based on quasi-BICs.

10.
Opt Express ; 31(13): 20740-20749, 2023 Jun 19.
Article in English | MEDLINE | ID: mdl-37381190

ABSTRACT

We proposed and demonstrated a highly efficient sub-microscale focusing from a GaN green laser diode (LD) integrated with double-sided asymmetric metasurfaces. The metasurfaces consist of two nanostructures in a GaN substrate: nanogratings on one side and a geometric phase based metalens on the other side. When it was integrated on the edge emission facet of a GaN green LD, linearly polarized emission was firstly converted to the circularly polarized state by the nanogratings functioning as a quarter-wave plate, the phase gradient was then controlled by the metalens on the exit side. In the end, the double-sided asymmetric metasurfaces achieve a sub micro-focusing from linearly polarized states. Experimental results show the full width at half maximum of the focused spot size is about 738 nm at the wavelength 520 nm and the focusing efficiency is about 72.8%. Our results lay a foundation for the multi-functional applications in optical tweezers, laser direct writing, visible light communication, and biological chip.

11.
Nanoscale ; 14(39): 14801-14806, 2022 Oct 13.
Article in English | MEDLINE | ID: mdl-36193682

ABSTRACT

We report an ultra-broadband metasurface perfect absorber from the UV to NIR region based on TiN nanostructures. A polarization-independent experimental average absorption of 0.900 (0.921 in simulation) at the wavelength band from 300 nm to 1500 nm is realized with only an 82 nm-thick TiN layer with TiO2 and MgF2 on top, which is efficiently fabricated by utilizing double-beam UV interference lithography followed by sputter coating deposition. A TiN-TiO2 hot-electron photoelectric conversion system is also simulated. An IPCE of 4% is realized at the wavelength of 710 nm and the average IPCE is 2.86% in the wavelength range of 400 nm to 1500 nm. The demonstrated device suggests an efficient way of designing and fabricating broadband perfect absorbers, which has great application potential in efficient hot-electron optoelectronic and photocatalytic systems.

12.
Light Sci Appl ; 10(1): 213, 2021 Oct 12.
Article in English | MEDLINE | ID: mdl-34642293

ABSTRACT

Glasses-free three-dimensional (3D) displays are one of the game-changing technologies that will redefine the display industry in portable electronic devices. However, because of the limited resolution in state-of-the-art display panels, current 3D displays suffer from a critical trade-off among the spatial resolution, angular resolution, and viewing angle. Inspired by the so-called spatially variant resolution imaging found in vertebrate eyes, we propose 3D display with spatially variant information density. Stereoscopic experiences with smooth motion parallax are maintained at the central view, while the viewing angle is enlarged at the periphery view. It is enabled by a large-scale 2D-metagrating complex to manipulate dot/linear/rectangular hybrid shaped views. Furthermore, a video rate full-color 3D display with an unprecedented 160° horizontal viewing angle is demonstrated. With thin and light form factors, the proposed 3D system can be integrated with off-the-shelf purchased flat panels, making it promising for applications in portable electronics.

13.
Opt Express ; 29(18): 28549-28561, 2021 Aug 30.
Article in English | MEDLINE | ID: mdl-34614982

ABSTRACT

Conventional diffractive optical elements suffer from large chromatic aberration due to its nature of severe dispersion so that they can only work at a single wavelength with near zero bandwidth. Here, we propose and experimentally demonstrate an achromatic imaging in the full-visible wavelength range with a single dual-pinhole-coded diffractive photon sieve (PS). The pinhole pattern (i.e., distribution of the position and size of each pinhole) is generated with dual wavelength-multiplexing coding (WMC) and wavefront coding (WFC), in which WMC makes multiple wavelengths that are optimally selected within the full visible range focus coherently on a common designed focal length while WFC expands the bandwidth of the diffracted imaging at each of the selected wavelengths. Numerical simulations show that when seven wavelengths (i.e., 484.8, 515.3, 547.8, 582.4, 619.1, 658.1 and 699.5 nm) within the visible range between 470 nm to 720 nm and a cubic wavefront coding parameter α = 30π are selected, a broadband achromatic imaging can be obtained within the full range of visible wavelength. Experimental fabrication of the proposed dual-pinhole-coded PS with a focal length of 500 mm and a diameter of 50 mm are performed using the mask-free UV-lithography. The experimental imaging results agree with the numerical results. The demonstrated work provides a novel and practical way for achieving achromatic imaging in the full visible range with features of thin, light and planar.

14.
Opt Express ; 29(20): 31902-31914, 2021 Sep 27.
Article in English | MEDLINE | ID: mdl-34615272

ABSTRACT

Broadband achromatic metalens imaging is of great interest in various applications, such as integrated imaging and augmented/virtual reality display. Current methods of achromatic metalenses mainly rely on the compensation of a linear phase dispersion implemented with complex nanostructures. Here, we propose and experimentally demonstrate a polarization-insensitive achromatic metalens (PIA-ML) based on computational wavefront coding. In this method, simple circular or square nanopillars are individually coded such that the focal depths at wavelengths at both ends of the achromatic bandwidth overlap at the designed focal plane, which removes the limitation of requiring a linear phase dispersion. An optimized PIA-ML that works in the full optical communication band from 1300 to 1700nm was obtained using a particle swarm optimization algorithm. Experimental results show that both focusing and imaging of the fabricated metalens are consistent with theoretical predictions within the broadband wavelength range, which provides a new methodology for ultra-broadband achromatic imaging with simple-shaped nanostructures.

15.
Disabil Health J ; 14(4): 101109, 2021 10.
Article in English | MEDLINE | ID: mdl-33933399

ABSTRACT

BACKGROUND: Musculoskeletal (MSK) disorder in adults with cerebral palsy (CP) is higher than in the general population. Evidence lacks about physical therapy (PT) and occupational therapy (OT) service utilization among older adults (65> years) living with CP. OBJECTIVE: We compared the presence of comorbidities and patterns of PT and OT use among older adults with and without CP seeking care for MSK disorders. METHODS: A 20% national sample of Medicare claims data (2011-2014) identified community-living older adults with (n = 8796) and without CP (n = 5,613,384) with one or more ambulatory claims for MSK diagnoses. The sample matched one CP case to two non-CP cases per year on MSK diagnoses, age, sex, race, dual eligibility, and census region. Exposure variable was the presence/absence of a CP diagnosis. Outcomes were use of PT and OT services identified via CPT and revenue center codes, and the presence/absence of Elixhauser comorbidities. RESULTS: In older adults with MSK diagnoses, less than a third regularly utilized PT and/or OT services, and adults with CP utilized significantly less PT than adults without CP, and for some MSK diagnoses had fewer visits than their matched peers. Older adults with CP were at greater risk for secondary conditions that influence morbidity, mortality, and quality of life compared to their age-matched peers without CP. CONCLUSIONS: Older adults with CP and MSK diagnoses had a greater prevalence of numerous comorbidities and lower use of PT services relative to their non-CP peers.


Subject(s)
Cerebral Palsy , Disabled Persons , Occupational Therapy , Aged , Cerebral Palsy/complications , Humans , Medicare , Quality of Life , United States
16.
Sci Rep ; 11(1): 8956, 2021 Apr 26.
Article in English | MEDLINE | ID: mdl-33903704

ABSTRACT

We report on a non-sharp-corner quarter wave plate (NCQW) within the single layer of only 8 nm thickness structured by the Ag hollow elliptical ring array, where the strong localized surface plasmons (LSP) resonances are excited. By manipulating the parameters of the hollow elliptical ring, the transmitted amplitude and phase of the two orthogonal components are well controlled. The phase difference of π/2 and amplitude ratio of 1 is realized simultaneously at the wavelength of 834 nm with the transmission of 0.46. The proposed NCQW also works well in an ultrawide wavelength band of 110 nm, which suggests an efficient way of exciting LSP resonances and designing wave plates, and provides a great potential for advanced nanophotonic devices and integrated photonic systems.

17.
iScience ; 23(1): 100773, 2020 Jan 24.
Article in English | MEDLINE | ID: mdl-31887666

ABSTRACT

Glasses-free three-dimensional (3D) display is considered as a potential disruptive technology for display. The issue of visual fatigue, mainly caused by the inaccurate phase reconstruction in terms of image crosstalk, as well as vergence and accommodation conflict, is the critical obstacle that hinders the real applications of glasses-free 3D display. Here we propose a glasses-free 3D display by adopting metagratings for the pixelated phase modulation to form converged viewpoints. When the viewpoints are closely arranged, the holographic sampling 3D display can approximate a continuous light field. We demonstrate a video rate full-color 3D display prototype without visual fatigue under an LED white light illumination. The metagratings-based holographic sampling 3D display has a thin form factor and is compatible with traditional flat panel and thus has the potential to be used in portable electronics, window display, exhibition display, 3D TV, as well as tabletop display.

18.
Opt Lett ; 44(16): 3984-3987, 2019 Aug 15.
Article in English | MEDLINE | ID: mdl-31415528

ABSTRACT

An all-dielectric double-layer grid grating is proposed and demonstrated theoretically and experimentally to realize the angular filtering effect. The theoretical results show that the transmission of the double-layer grid grating drops sensitively, as the incident angle increases under TM incidence at the designed resonant wavelength. The transmission is almost 0 (i.e., the entire incident light is reflected) when the incident angle increases to over 12°, which exhibits excellent angular filtering behavior. Double-beam interference lithography and sputter coated depositions are utilized to fabricate the proposed angular filter. The experimental results show that the divergent angle of the transmitted beam through the angular filtering sample at the wavelength of 633 nm is 7.76°, and the transmission is as high as 0.936 at normal incidence. The ultra-thin all-dielectric angular filter is very easy to fabricate in a large area, which has important applications in directional lighting and image processing.

19.
Opt Express ; 26(16): 21141-21152, 2018 Aug 06.
Article in English | MEDLINE | ID: mdl-30119418

ABSTRACT

Conventional photon sieves suffer from large chromatic aberration due to diffractive nature and can image only at a single designed wavelength with near zero bandwidth. Here, a novel photon sieve that can image achromatically and simultaneously at multiple wavelengths with wide spectral bandwidth is proposed and demonstrated experimentally. The multispectral achromatic imaging with a single diffractive photon sieve is implemented with harmonic diffraction and wavefront coding, in which harmonic diffraction makes different diffracted orders of multiple harmonic wavelengths on a common focus while wavefront coding through the coded distribution of the pinholes expands the bandwidth of diffracted imaging. Numerical simulations show that when four spectral bands centered at 437.5, 500, 583.3, and 700 nm in the visible range is designed with a cubic wavefront coding parameter α = 30π and a harmonic diffraction order of 5, the bandwidth at the corresponding wavelength band can reach ± 8, ± 9, ± 11 and ± 14 nm respectively, and the total working bandwidth of the harmonic diffraction wavefront coded photon sieve reaches ~84 nm compared with 0.39 nm of the conventional one. Experimental validation was performed using an UV-lithography fabricated wavefront coded photon sieve of a focal length of 500 mm and a diameter of 50 mm at a designed wavelength of 700 nm. The results show excellent agreement with the theoretical predictions.

20.
Opt Lett ; 43(6): 1231-1234, 2018 Mar 15.
Article in English | MEDLINE | ID: mdl-29543259

ABSTRACT

We report on a monolithic, all-metallic, and flexible metasurface perfect absorber [black nickel (Ni)] based on coupled Mie resonances originated from vertically stepped Ni nanopillars homoepitaxially grown on an Ni substrate. Coupled Mie resonances are generated from Ni nanopillars with different sizes such that Mie resonances of the stepped two sets of Ni nanopillars occur complementarily at different wavelengths to realize polarization-independent broadband absorption over the entire visible wavelength band (400-760 nm) within an ultra-thin surface layer of only 162 nm thick in total. Two-step double-beam interference lithography and electroplating are utilized to fabricate the proposed monolithic metasurface that can be arbitrarily bent and pressed. A black nickel metasurface is experimentally demonstrated in which an average polarization-independent absorption of 0.972 (0.961, experiment) in the entire visible band is achieved and remains 0.838 (0.815, experiment) when the incident angle increases to 70°.

SELECTION OF CITATIONS
SEARCH DETAIL
...