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1.
Cell Transplant ; 32: 9636897231167213, 2023.
Article in English | MEDLINE | ID: mdl-37085967

ABSTRACT

Individuals with brachial plexus injury (BPI) require upper limb function restoration, but the treatment remains controversial. Vitamin B12 may aid in pain control and nerve regeneration. We present the technical aspects of ultrasound-guided perineural vitamin B12 injection for BPI. The demonstrative case is a 50-year-old man with BPI resulting from a traffic accident. Under ultrasound guidance, vitamin B12 was injected precisely into the brachial plexus compartment around the swollen neuroma of the C6 root. Motor and sensory functions of the left upper extremity improved over 6 months. Ultrasound-guided perineural vitamin B12 injection may be an efficient and personalized intervention in cases of post-ganglionic BPI that failed to improve in the first 3 months.


Subject(s)
Brachial Plexus , Male , Humans , Middle Aged , Brachial Plexus/diagnostic imaging , Brachial Plexus/injuries , Pain Management , Vitamin B 12/therapeutic use , Thorax , Ultrasonography, Interventional/methods
2.
Medicine (Baltimore) ; 100(35): e27099, 2021 Sep 03.
Article in English | MEDLINE | ID: mdl-34477146

ABSTRACT

ABSTRACT: Transcatheter occlusion and surgical ligation are the treatments of choice for most patent ductus arteriosus (PDA) in children. Fifty-five children who had PDA completed a pulmonary function test and a symptom-limited treadmill exercise test from 2016 to 2018 at 1 medical center in southern Taiwan. The study group was divided into surgical ligation and catheterization groups, which were compared to a healthy control group matched for age, sex, and body mass index. Data about the performance on the exercise test, including metabolic equivalent at anaerobic threshold and peak, were analyzed. No differences in the pulmonary function and ventilatory parameters were observed between the surgery, catheterization, and control groups. Heart rate at peak and at anaerobic threshold significantly differed in the investigated groups. The post hoc analysis showed that the surgery group had a lower heart rate at peak and threshold compared to the catheterization and control groups (P = .02, P < .001, respectively). No significant difference was found between the catheterization group and the control group. A larger and younger group of patients were recruited, allowing for newer data about the cardiopulmonary function to be obtained. The findings suggest that patients with PDA could undergo physical training after intervention. The imposition of restrictions to limit sports activities should be avoided.


Subject(s)
Cardiac Output/physiology , Ductus Arteriosus, Patent/complications , Heart Function Tests/statistics & numerical data , Cardiac Catheterization/methods , Cardiac Catheterization/statistics & numerical data , Child , Ductus Arteriosus, Patent/physiopathology , Female , Heart Function Tests/methods , Humans , Male , Pediatrics/methods , Treatment Outcome
3.
Sci Rep ; 7(1): 13557, 2017 10 19.
Article in English | MEDLINE | ID: mdl-29051548

ABSTRACT

Spontaneous subarachnoid hemorrhage (SAH) is a devastating disease, and gastrointestinal hemorrhage is one of several potential complications of acute strokes. We aim to analyze its prevalence, risk factors, and association with in-hospital prognosis following SAH. A total of 1047 adult patients with a primary diagnosis of spontaneous SAH were retrospectively enrolled. We retrieved medical information from the administrative database utilizing diagnostic and procedure codes of the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM). Patients with SAH included 418 men and 629 women, and their mean age was 57.2 (standard deviation 14.6) years (range, 18-93 years). Gastrointestinal hemorrhage occurred in 30 of the 1047 patients, accounting for 2.9%. In a multivariate logistic regression model, the independent risk factors for gastrointestinal hemorrhage were liver disease and hydrocephalus. The in-hospital mortality rates were 43.3% and 29.3% in patients with and without gastrointestinal hemorrhage, respectively, but the difference was not statistically significant. In conclusion, the prevalence of gastrointestinal hemorrhage was 2.9% in patients hospitalized for spontaneous SAH. Underlying liver disease and the presence of hydrocephalus were both independent risk factors for this complication, which is a reminder to clinicians to pay increased attention in such cases.


Subject(s)
Gastrointestinal Hemorrhage/diagnosis , Subarachnoid Hemorrhage/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , Cohort Studies , Female , Gastrointestinal Hemorrhage/complications , Gastrointestinal Hemorrhage/epidemiology , Hospital Mortality , Humans , Hydrocephalus/complications , Hydrocephalus/pathology , Kaplan-Meier Estimate , Liver Diseases/complications , Liver Diseases/pathology , Logistic Models , Male , Middle Aged , Prevalence , Retrospective Studies , Risk Factors , Subarachnoid Hemorrhage/complications , Subarachnoid Hemorrhage/mortality , Young Adult
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