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1.
PLoS One ; 17(3): e0265629, 2022.
Article in English | MEDLINE | ID: mdl-35320301

ABSTRACT

BACKGROUND: Aging-related hypogonadism in men is related to the deterioration of overall health. Those with this disease rarely receive treatment. The hypertriglyceridemic waist (HTGW) phenotype is a tool for predicting abnormalities of cardiovascular metabolism. However, the relationship between the HTGW phenotype and hypogonadism remains undetermined. This study aimed to determine the association between HTGW phenotype and hypogonadism in different age groups. METHODS: Data of this cross-sectional study were obtained from MJ Health Screening Center in Taiwan from 2007 to 2016. The HTGW phenotype was divided into four categories based on whether the waist circumference (WC) and triglyceride levels were normal. WC of <90 cm and triglyceride level of <150 mg/dL were defined as normal. Hypogonadism was defined as a testosterone level of <300 ng/dL. RESULTS: Overall, 6442 male participants were divided into three age groups: <50, 50-64, and ≥65 years (n = 4135, 1958, and 349; age groups 1, 2, and 3, respectively). The overall prevalence of hypogonadism was 10.6%. In group 1, participants with HTGW (odds ratio, 1.98; 95% confidence interval (CI), 1.354-2.896) had a higher risk of hypogonadism than those with normal WC and normal triglyceride levels after adjustment for body mass index and fasting blood glucose level. In group 2, participants with HTGW (odds ratio, 1.873; 95% CI, 1.099-3.193) had an increased risk of hypogonadism after adjustment for body mass index, fasting blood glucose level, Cholesterol levels, high-density lipoprotein (HDL) levels, low-density lipoprptein (LDL) levels and smoking status. However, no relationship was observed between HTGW phenotype and hypogonadism in group 3. CONCLUSION: HTGW phenotype was highly associated with hypogonadism in Taiwanese adult men. More attention should be paid to men aged <50 years with HTGW.


Subject(s)
Hypertriglyceridemic Waist , Hypogonadism , Blood Glucose , Cross-Sectional Studies , Female , Humans , Hypertriglyceridemic Waist/complications , Hypertriglyceridemic Waist/epidemiology , Hypogonadism/complications , Hypogonadism/epidemiology , Male , Phenotype , Risk Factors , Triglycerides , Waist Circumference
2.
BMJ Open ; 11(1): e040424, 2021 01 13.
Article in English | MEDLINE | ID: mdl-33441354

ABSTRACT

OBJECTIVES: This study examined the associations between the Second-Generation Cessation Payment Scheme (SCPS) and the use of smoking cessation treatments. Furthermore, these associations were compared between light and heavy smokers in Taiwan. DESIGN: This study had a cross-sectional design. SETTING: Data were obtained from the Taiwan Adult Smoking Behaviour Surveillance System 2010-2011 and 2013-2014; data for each year consisted of a nationally representative sample of adults aged 18 years and older. PARTICIPANTS: Current smokers who had either quit or made a serious attempt to quit smoking were selected for the analysis. PRIMARY OUTCOME MEASURE: The primary outcome measure was the use of a smoking cessation clinic or pharmacy in a twice daily to quit smoking. RESULTS: According to multivariate analysis, the SCPS was positively associated with the combined use of a smoking cessation clinic and a pharmacy (OR=3.947; 95% CI: 1.359 to 11.463) when individual-level predictors (gender, age, education level, marital status, monthly household income, daily cigarette consumption, smoking status and self-reported health) were controlled. Heavy smokers showed a significant increase in the sole use of a pharmacy (OR=1.676; 95% CI: 1.094 to 2.569) and combined use of a smoking cessation clinic and pharmacy (OR=8.984; 95% CI: 1.914 to 42.173) after the SCPS was introduced. In addition, when related factors were controlled, the use of smoking cessation services was more frequent among heavy smokers than light smokers, including any treatment (OR=1.594; 95% CI: 1.308 to 1.942), a smoking cessation clinic (OR=1.539; 95% CI: 1.232 to 1.922), a pharmacy (OR=1.632; 95% CI: 1.157 to 2.302) and the combination of a smoking cessation clinic and pharmacy (OR=4.608; 95% CI: 1.331 to 15.949) . CONCLUSIONS: The SCPS subsidisation policy increased the use of smoking cessation treatments, particularly among heavy smokers.


Subject(s)
Smoking Cessation , Adolescent , Adult , Cross-Sectional Studies , Government , Humans , Policy , Taiwan/epidemiology
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