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1.
Rehabil Psychol ; 2024 Feb 15.
Article in English | MEDLINE | ID: mdl-38358711

ABSTRACT

PURPOSE/OBJECTIVE: This study sought to develop and evaluate the psychometric properties of a brief measure of the quality of therapist treatment delivery that would be applicable for use across different types of psychosocial chronic pain treatments: the Therapist Quality Scale (TQS). RESEARCH METHOD/DESIGN: An initial pool of 14 items was adapted from existing measures, with items selected that are relevant across interventions tested in a parent trial comparing an 8-week, group, Zoom-delivered mindfulness meditation, cognitive therapy, and behavioral activation for chronic back pain from which data for this study were obtained. A random selection of 25% of video-recorded sessions from each cohort was coded for therapist quality (two randomly selected sessions per group), with 66 sessions included in the final analyses (n = 33 completed pairs). Items were coded on a 7-point Likert-type scale. Exploratory factor analysis (EFA) and reliability estimates were generated. RESULTS: EFA showed a single-factor solution that provided a parsimonious explanation of the correlational structure for both sessions. Eight items with factor loadings of ≥ .60 in both sessions were selected to form the TQS. Reliability analyses demonstrated all items contributed to scale reliability, and internal consistency reliabilities were good (αs ≥ .86). Scores for the eight-item TQS from the two sessions were significantly correlated (r = .59, p < .001). CONCLUSIONS/IMPLICATIONS: The TQS provides a brief measure with preliminary psychometric support that is applicable for use across different types of treatments to rate the quality of the therapist's delivery. The items assess quality in delivering specific techniques, maintaining session structure, and in developing and maintaining therapeutic rapport. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

2.
Eur J Pain ; 26(2): 505-521, 2022 02.
Article in English | MEDLINE | ID: mdl-34698421

ABSTRACT

BACKGROUND: The behavioural inhibition system and activation system (BIS-BAS) model of pain focusses on two clusters of responses to pain-escape/avoidance (BIS) and approach (BAS) behaviours. While the BIS-BAS model emphasizes active responses to pain, deactivation responses such as despondence and relaxation are also common. This study sought to develop self-report scales assessing cognitive, behavioural intentions and affective responses to pain consistent with this extended BIS-BAS framework. We also sought to develop short-forms of the emerging scales. METHODS: Confirmatory factor analysis was performed to derive scales from a large item pool administered to a community sample with heterogeneous chronic pain (N = 476). RESULTS: The items resulted in 16 scales assessing Thoughts, Affective responses, Behavioural Intentions and Valence-Associated Thoughts, which loaded on to the four theorized types of pain responses-Escape, Approach, Despondence and Relaxation-with the four emerging short-form scales assessing these overarching factors. The internal consistency reliabilities of the long-forms generally ranged from good to excellent (αs ≥ 0.83), with the exception of the Relaxation-Behavioural Intentions scale (α = 0.64). The four short-forms demonstrated at least adequate internal consistency reliability (αs ≥ 0.79). An initial test of the construct validity of the scales in relation to pain-related outcomes is also reported. CONCLUSIONS: We anticipate that the Pain Responses Scale (PRS) developed from this research will be useful for assessing mechanisms targeted by many psychosocial pain treatments and will provide a nuanced understanding of the shared versus specific nature of these mechanisms. SIGNIFICANCE: The Pain Responses Scale emerging from this research assesses four theorized, overarching responses to pain: Escape, Approach, Giving Up and Relaxation. This measure will afford the capacity to test a reconceptualized BIS-BAS model of pain and inform treatments that are adapted based on this framework.


Subject(s)
Chronic Pain , Inhibition, Psychological , Chronic Pain/diagnosis , Factor Analysis, Statistical , Humans , Pain Measurement , Psychometrics , Reproducibility of Results
3.
Clin J Pain ; 36(10): 740-749, 2020 10.
Article in English | MEDLINE | ID: mdl-32694318

ABSTRACT

OBJECTIVES: This study evaluated theoretically derived mechanisms and common therapeutic factors to test their role in accounting for pain-related outcome change during group-delivered cognitive therapy, mindfulness meditation, and mindfulness-based cognitive therapy for chronic low back pain. METHODS: A secondary analysis of a pilot randomized controlled trial was used to explore the primary mechanisms of pretreatment to posttreatment changes in pain control beliefs, mindful observing, and pain catastrophizing, and the secondary common factor mechanisms of therapeutic alliance, group cohesion, and amount of at-home skill practice during treatment. The primary outcome was pain interference; pain intensity was a secondary outcome. RESULTS: Large effect size changes in the 3 primary mechanisms and the outcome variables were found across the conditions. Across all 3 treatment conditions, change in pain control beliefs and pain catastrophizing were significantly associated with improved pain interference, but not pain intensity. Therapeutic alliance was significantly associated with pain intensity improvement and change in the therapy-specific mechanisms across the 3 conditions. Mindful observing, group cohesion, and amount of at-home practice were not significantly associated with changes in the outcomes. DISCUSSION: Cognitive therapy, mindfulness meditation, and mindfulness-based cognitive therapy for chronic low back pain were all associated with significant changes in the primary mechanisms to a similar degree. Change in perceived pain control and pain catastrophizing emerged as potential "meta-mechanisms" that might be a shared pathway that contributes to improved pain-related outcomes across treatments. Further, strong working alliance may represent a critical therapeutic process that both promotes and interacts with therapeutic techniques to influence outcome.


Subject(s)
Cognitive Behavioral Therapy , Low Back Pain , Meditation , Mindfulness , Psychotherapy, Group , Chronic Pain/therapy , Humans , Low Back Pain/therapy , Treatment Outcome
4.
Eur J Pain ; 24(6): 1072-1083, 2020 07.
Article in English | MEDLINE | ID: mdl-32115805

ABSTRACT

BACKGROUND: This study reports a multivariate test of sex and race differences in experimental pain, and the degree to which these differences could be uniquely attributable to three levels of cognition: primary appraisals (threat, challenge), secondary appraisals (pain catastrophizing) and/or cognitive processes (mindful observing, non-reactivity). Both the predictive and mediator role of the cognitive variables was of interest. METHODS: The study employed a cross-sectional experimental design, with the cold pressor task employed as the pain stimulus. The total sample included N = 355 healthy adults (67% female, 33% male; 70% Caucasian, 30% Asian). RESULTS: Significant sex and race differences on pain tolerance were found, with females and racial minorities reporting less pain tolerance (ps < 0.001). Males reported significantly higher challenge appraisals and non-reactivity, and lower pain catastrophizing than females; Asians reported significantly higher threat appraisals and pain catastrophizing than Caucasians. In multivariate analyses, challenge appraisals and non-reactivity emerged as the strongest predictors of pain tolerance. Furthermore, challenge appraisals mediated the sex-pain tolerance association (p = .017). CONCLUSIONS: This study showed that race and sex differences, at least in part, may be accounted for by differences in pain-related cognitions. SIGNIFICANCE: The three levels of cognition investigated in this research represent changeable, important processes for potentially mitigating the impact of pain in vulnerable groups.


Subject(s)
Adaptation, Psychological , Pain , Cognition , Cross-Sectional Studies , Female , Humans , Male , Pain Threshold
5.
Pain Med ; 20(11): 2134-2148, 2019 11 01.
Article in English | MEDLINE | ID: mdl-30605517

ABSTRACT

OBJECTIVE: This pilot trial compared the feasibility, tolerability, acceptability, and effects of group-delivered mindfulness meditation (MM), cognitive therapy (CT), and mindfulness-based cognitive therapy (MBCT) for chronic low back pain (CLBP). SETTING: University of Queensland Psychology Clinic. SUBJECTS: Participants were N = 69 (intent-to-treat [ITT] sample) adults with CLBP. DESIGN: A pilot, assessor-blinded randomized controlled trial. METHODS: Participants were randomized to treatments. The primary outcome was pain interference; secondary outcomes were pain intensity, physical function, depression, and opioid medication use. The primary study end point was post-treatment; maintenance of gains was evaluated at three- and six-month follow-up. RESULTS: Ratings of acceptability, and ratios of dropout and attendance showed that MBCT was acceptable, feasible, and well tolerated, with similar results found across conditions. For the ITT sample, large improvements in post-treatment scores for pain interference, pain intensity, physical function, and depression were found (P < 0.001), with no significant between-group differences. Analysis of the follow-up data (N = 43), however, revealed that MBCT participants improved significantly more than MM participants on pain interference, physical function, and depression. The CT group improved more than MM in physical function. The MBCT and CT groups did not differ significantly on any measures. CONCLUSIONS: This is the first study to examine MBCT for CLBP management. The findings show that MBCT is a feasible, tolerable, acceptable, and potentially efficacious treatment option for CLBP. Further, MBCT, and possibly CT, could have sustained benefits that exceed MM on some important CLBP outcomes. A future definitive randomized controlled trial is needed to evaluate these treatments and their differences.


Subject(s)
Chronic Pain/therapy , Cognitive Behavioral Therapy , Low Back Pain/therapy , Meditation , Mindfulness , Adult , Analgesics, Opioid/therapeutic use , Cognitive Behavioral Therapy/methods , Depression/psychology , Female , Humans , Male , Meditation/methods , Middle Aged , Mindfulness/methods , Pain Measurement , Psychotherapy, Group
6.
Clin J Pain ; 34(8): 723-731, 2018 08.
Article in English | MEDLINE | ID: mdl-29298185

ABSTRACT

BACKGROUND: The Pain-related Cognitive Processes Questionnaire (PCPQ) provides a multifaceted assessment of different styles of pain-related attentional processing. The present study examined the construct validity of the 4 PCPQ composite scales. METHODS: Exploratory structural equation modeling was applied to data from 2 college student samples (N=544) to derive reference-variable factors that provided the context for drawing inferences regarding the construct validity of the PCPQ scales. RESULTS: PCPQ scales were regressed on 8 orthogonal reference-variable factors that captured the common variance in 17 pain-related measures. A substantial proportion of the variance in the PCPQ Pain Diversion scale was predicted by factors reflecting: (1) use of distraction to reduce negative thoughts; (2) belief in the ability to control pain; and (3) pain catastrophizing. The PCPQ Pain Distancing scale was associated with factors reflecting: (1) belief in control over pain; (2) use of distraction; (3) efforts to punish negative thoughts; and (4) pain disability. PCPQ Pain Focus was predicted mostly by a factor reflecting pain catastrophizing, although emotional distress contributed an additional amount of variance. The PCPQ Pain Openness scale had a small negative relationship with the factor reflecting pain catastrophizing. CONCLUSIONS: The associations found in the exploratory structural equation modeling approach, as well as the PCPQ scale content and intercorrelations, support the validity of the PCPQ Pain Diversion, Pain Distancing, and Pain Focus scales. Given the lack of strong associations with the validity criteria assessed in this study, questions remain regarding the construct validity of the Pain Openness scale.


Subject(s)
Cognition , Pain/psychology , Surveys and Questionnaires , Adaptation, Psychological , Adolescent , Adult , Anxiety , Attention , Catastrophization/psychology , Cross-Sectional Studies , Depression , Disability Evaluation , Female , Health Knowledge, Attitudes, Practice , Humans , Latent Class Analysis , Male , Middle Aged , Multivariate Analysis , Pain Measurement , Personal Satisfaction , Young Adult
7.
Pain Med ; 19(2): 269-283, 2018 02 01.
Article in English | MEDLINE | ID: mdl-28340114

ABSTRACT

Objective: Cognitive processes may be characterized as how individuals think, whereas cognitive content constitutes what individuals think. Both cognitive processes and cognitive content are theorized to play important roles in chronic pain adjustment, and treatments have been developed to target both. However, the evaluation of treatments that target cognitive processes is limited because extant measures do not satisfactorily separate cognitive process from cognitive content. The current study aimed to develop a self-report inventory of potentially adaptive and presumed maladaptive attentional processes that may occur when someone is experiencing pain. Methods: Scales were derived from a large item pool by successively applying confirmatory factor analysis to item data from two undergraduate samples (N = 393 and 233). Results: Items, which were generated to avoid confounding of cognitive content with cognitive processes, represented nine constructs: Suppression, Distraction, Enhancement, Dissociation, Reappraisal, Absorption, Rumination, Nonjudgment, and Acceptance. The resulting nine scales formed the Pain-Related Cognitive Process Questionnaire (PCPQ), and scale correlations produced four conceptually distinct composite scales: Pain Diversion, Pain Distancing, Pain Focus, and Pain Openness. Internal consistency reliabilities of the nine scales were adequate (α ≥ 0.70) to good, and the four composite scales had α values of 0.79 or higher. Correlations with pain-related criterion variables were generally consistent with putative constructs. Conclusions: The developed PCPQ scales offer a comprehensive assessment of important cognitive processes specific to pain. Overall, the findings suggest that the PCPQ scales may prove useful for evaluating the role of pain-related cognitive processes in studies of chronic pain.


Subject(s)
Chronic Pain/psychology , Psychometrics/instrumentation , Surveys and Questionnaires , Female , Humans , Male , Young Adult
8.
Clin J Pain ; 33(4): 325-334, 2017 04.
Article in English | MEDLINE | ID: mdl-27428549

ABSTRACT

OBJECTIVES: We recently proposed a Behavioral Inhibition System-Behavioral Activation System (BIS-BAS) model to help explain the effects of pain treatments. In this model, treatments are hypothesized to operate primarily through their effects on the domains within 2 distinct neurophysiological systems that underlie approach (BAS) and avoidance (BIS) behaviors. Measures of the model's domains are needed to evaluate and modify the model. METHODS: An item pool of negative responses to pain (NRP; hypothesized to be BIS related) and positive responses (PR; hypothesized to be BAS related) were administered to 395 undergraduates, 325 of whom endorsed recurrent pain. The items were administered to 176 of these individuals again 1 week later. Analyses were conducted to develop and validate scales assessing NRP and PR domains. RESULTS: Three NRP scales (Despondent Response to Pain, Fear of Pain, and Avoidant Response to Pain) and 2 PR scales (Happy/Hopeful Responses and Approach Response) emerged. Consistent with the model, the scales formed 2 relatively independent overarching domains. The scales also demonstrated excellent internal consistency, and associations with criterion variables supported their validity. However, whereas the NRP scales evidenced adequate test-retest stability, the 2 PR scales were not adequately stable. DISCUSSION: The study yielded 3 brief scales assessing NRP, which may be used to further evaluate the BIS-BAS model and to advance research elucidating the mechanisms of psychosocial pain treatments. The findings also provide general support for the BIS-BAS model, while also suggesting that some minor modifications in the model are warranted.


Subject(s)
Avoidance Learning , Cognition , Emotions , Motivation , Pain/diagnosis , Pain/psychology , Factor Analysis, Statistical , Fear , Female , Humans , Male , Pain Measurement , Psychiatric Status Rating Scales , Reproducibility of Results
9.
Clin J Pain ; 32(2): 155-63, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26741742

ABSTRACT

OBJECTIVES: Pain is a significant problem for many individuals with multiple sclerosis (MS). Pain is often associated with other MS symptoms (eg, physical, sensorimotor, cognitive declines), and both pain and MS symptoms are hypothesized to contribute to psychosocial problems (eg, depression), other symptoms (eg, fatigue, sleep disturbance), and functional impairments (eg, pain interference). On the basis of a biopsychosocial model, we sought to: (1) examine the associations between pain, MS symptoms, depression, psychosocial, and functional variables and (2) identify possible risk and protective factors associated with pain in MS. MATERIALS AND METHODS: A cross-sectional survey was completed by 424 individuals with MS. Pain, MS symptoms, demographics, MS diagnostic factors, and psychosocial and functional variables were assessed. Data were analyzed by structural equation models. RESULTS: Participants were predominantly white (92%), middle-aged (mean=50.7 y), and female (80%). Results indicated that pain severity and depression accounted for >50% of the variance in pain interference. Although pain contributed minimally to fatigue and sleep quality, depression and MS symptoms predicted 49% of the variance in fatigue, and depression was largely responsible for the 40% of predicted variance in sleep quality. Identified risk factors for pain were low educational attainment and lack of a committed/marital relationship, even while controlling for diagnostic and other key demographic variables. DISCUSSION: Results highlight the importance of targeting interventions toward improving coping skills and social support within the context of pain and MS. Research is needed to determine whether effectively targeting depression in MS results in improvements of other critical psychosocial and physical functioning domains.


Subject(s)
Depression/etiology , Fatigue/etiology , Multiple Sclerosis/complications , Multiple Sclerosis/psychology , Pain/etiology , Activities of Daily Living , Adult , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Models, Statistical , Pain Measurement , Psychiatric Status Rating Scales , Risk Factors , Self Report , Young Adult
10.
Clin J Pain ; 31(3): 222-8, 2015 Mar.
Article in English | MEDLINE | ID: mdl-24699159

ABSTRACT

OBJECTIVE: Mindfulness and pain catastrophizing are important constructs in pain research, and there are theoretical reasons for suspecting that measures of the 2 constructs should be related in predictable ways. The present study investigated the association of pain catastrophizing (Pain Catastrophizing Scale) with mindfulness (Five Facet Mindfulness Questionnaire). The Penn State Worry Questionnaire was included to control for confounding of worry; the influence of demographics was explored. METHODS: The participants were 214 undergraduates, who were administered questionnaires via the Internet. Analyses assessed relationships after correcting for attenuation. RESULTS: The mindfulness scales had intercorrelations with catastrophizing ranging from -0.23 to 0.13; the Non-Judging, Non-Reactivity, and Acting with Awareness mindfulness scales correlated significantly with catastrophizing. However, worry was better correlated (r=0.35) with catastrophizing, and the mindfulness scales were not significantly related to catastrophizing after controlling for worry. Mindfulness scales were significant predictors (P=0.018) of catastrophizing scores in a single-indicator latent variable analysis, and 1 mindfulness scale (Non-Reactivity) contributed uniquely (P=0.006) to prediction. None of the mindfulness scales significantly predicted catastrophizing scores when worry was controlled, but the path from worry to catastrophizing was significant (P=0.048). Sex differences in catastrophizing scores were explained by sex differences on the worry scale (P<0.001). DISCUSSION: These findings suggest that it is important to assess more general cognitive-emotional constructs, such as worry, when making inferences about the influence of mindfulness or changes in mindfulness upon catastrophic thinking in response to pain.


Subject(s)
Awareness , Catastrophization/psychology , Catastrophization/rehabilitation , Mindfulness , Pain Measurement/psychology , Adult , Anxiety , Cross-Sectional Studies , Female , Follow-Up Studies , Humans , Male , Self Report , Surveys and Questionnaires , Young Adult
11.
Clin J Pain ; 30(2): 152-61, 2014 Feb.
Article in English | MEDLINE | ID: mdl-23446085

ABSTRACT

OBJECTIVE: This pilot study reports the findings of a randomized controlled trial (RCT) investigating the feasibility, tolerability, acceptability, and initial estimates of efficacy of mindfulness-based cognitive therapy (MBCT) compared to a delayed treatment (DT) control for headache pain. It was hypothesized that MBCT would be a viable treatment approach and that compared to DT, would elicit significant improvement in primary headache pain-related outcomes and secondary cognitive-related outcomes. MATERIALS AND METHODS: RCT methodology was employed and multivariate analysis of variance models were conducted on daily headache diary data and preassessment and postassessment data for the intent-to-treat sample (N=36), and on the completer sample (N=24). RESULTS: Patient flow data and standardized measures found MBCT for headache pain to be feasible, tolerable, and acceptable to participants. Intent-to-treat analyses showed that compared to DT, MBCT patients reported significantly greater improvement in self-efficacy (P=0.02, d=0.82) and pain acceptance (P=0.02, d=0.82). Results of the completer analyses produced a similar pattern of findings; additionally, compared to DT, MBCT completers reported significantly improved pain interference (P<0.01, d=-1.29) and pain catastrophizing (P=0.03, d=-0.94). Change in daily headache diary outcomes was not significantly different between groups (P's>0.05, d's≤-0.24). DISCUSSION: This study empirically examined MBCT for the treatment of headache pain. Results indicated that MBCT is a feasible, tolerable, acceptable, and potentially efficacious intervention for patients with headache pain. This study provides a research base for future RCTs comparing MBCT to attention control, and future comparative effectiveness studies of MBCT and cognitive-behavioral therapy.


Subject(s)
Cognitive Behavioral Therapy/methods , Headache Disorders/psychology , Headache Disorders/therapy , Mindfulness , Adult , Feasibility Studies , Female , Headache Disorders/drug therapy , Humans , Male , Middle Aged , Motivation , Pain Measurement , Patient Acceptance of Health Care , Patient Compliance , Patient Satisfaction , Pilot Projects , Sample Size , Self Efficacy , Socioeconomic Factors , Treatment Outcome
12.
Psychiatr Serv ; 63(5): 464-70, 2012.
Article in English | MEDLINE | ID: mdl-22307881

ABSTRACT

OBJECTIVE: Posttraumatic stress disorder (PTSD) is a potentially disabling mental illness that can cause occupational dysfunction. Although vocational rehabilitation is often prescribed for patients with PTSD, standard vocational services are far from adequate in helping them obtain and maintain competitive employment. This study is the first to examine the outcome of evidence-based supported employment for veterans with PTSD. METHODS: Unemployed veterans with PTSD were randomly assigned to either individual placement and support (IPS) supported employment (N = 42) or a Veterans Health Administration Vocational Rehabilitation Program (VRP) treatment as usual (N = 43). Employment rates and occupational outcomes were followed for 12 months. RESULTS: During the 12-month study, 76% of the IPS participants gained competitive employment, compared with 28% of the VRP participants (number needed to treat = 2.07; χ(2) = 19.84, df = 1, p<.001). Veterans assigned to IPS also worked substantially more weeks than those assigned to VRP (42% versus 16% of the eligible weeks, respectively; Mann-Whitney z test p<.001) and earned higher 12-month income (mean ± SD income of $9,264 ± $13,294 for IPS versus $2,601 ± $6,009 for VRP; Mann-Whitney z test p<.001) during the 12-month period. CONCLUSIONS: Veterans with PTSD who received IPS were 2.7 times more likely to gain competitive employment than those who received VRP. Because work is central to recovery, these results should assist stakeholders in planning improved services for veterans with PTSD.


Subject(s)
Employment, Supported , Outcome Assessment, Health Care/statistics & numerical data , Rehabilitation, Vocational/methods , Stress Disorders, Post-Traumatic/rehabilitation , Adult , Female , Humans , Intention to Treat Analysis , Kaplan-Meier Estimate , Male , Middle Aged , Social Adjustment , United States , United States Department of Veterans Affairs , Veterans/psychology , Young Adult
13.
Psychol Assess ; 24(2): 328-340, 2012 Jun.
Article in English | MEDLINE | ID: mdl-21928907

ABSTRACT

D. Wechsler (2008b) reported confirmatory factor analyses (CFAs) with standardization data (ages 16-69 years) for 10 core and 5 supplemental subtests from the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). Analyses of the 15 subtests supported 4 hypothesized oblique factors (Verbal Comprehension, Working Memory, Perceptual Reasoning, and Processing Speed) but also revealed unexplained covariance between Block Design and Visual Puzzles (Perceptual Reasoning subtests). That covariance was not included in the final models. Instead, a path was added from Working Memory to Figure Weights (Perceptual Reasoning subtest) to improve fit and achieve a desired factor pattern. The present research with the same data (N = 1,800) showed that the path from Working Memory to Figure Weights increases the association between Working Memory and Matrix Reasoning. Specifying both paths improves model fit and largely eliminates unexplained covariance between Block Design and Visual Puzzles but with the undesirable consequence that Figure Weights and Matrix Reasoning are equally determined by Perceptual Reasoning and Working Memory. An alternative 4-factor model was proposed that explained theory-implied covariance between Block Design and Visual Puzzles and between Arithmetic and Figure Weights while maintaining compatibility with WAIS-IV Index structure. The proposed model compared favorably with a 5-factor model based on Cattell-Horn-Carroll theory. The present findings emphasize that covariance model comparisons should involve considerations of conceptual coherence and theoretical adherence in addition to statistical fit.


Subject(s)
Intelligence/classification , Models, Psychological , Psychological Theory , Psychometrics/statistics & numerical data , Wechsler Scales/statistics & numerical data , Adolescent , Adult , Aged , Aged, 80 and over , Analysis of Variance , Data Interpretation, Statistical , Factor Analysis, Statistical , Humans , Mental Processes/physiology , Middle Aged , Psychometrics/standards , Reference Standards , Wechsler Scales/standards , Young Adult
14.
Behav Sleep Med ; 9(4): 266-72, 2011.
Article in English | MEDLINE | ID: mdl-22003980

ABSTRACT

This case study series investigated a new treatment for paradoxical insomnia patients as there is no standard treatment for this patient group at this time. Four paradoxical insomnia patients had a polysomnography (PSG) sleep study, an unsuccessful brief course of behavioral treatment for insomnia, and then a novel sleep education treatment comprising review of their PSG with video and exploration of the discrepancy between their reported and observed sleep experience. Two patients responded well to sleep education, mainly with improved self-reported sleep onset latency, total sleep time, and Insomnia Severity Index scores; and the other two, who exhibited sleep architecture anomalies, were unresponsive. These findings suggest that sleep education holds promise for some paradoxical insomnia patients. Suggestions for future studies are given.


Subject(s)
Patient Education as Topic , Sleep Initiation and Maintenance Disorders/therapy , Adult , Aged , Behavior Therapy , Female , Humans , Male , Middle Aged , Polysomnography , Severity of Illness Index , Sleep , Sleep Initiation and Maintenance Disorders/diagnosis , Treatment Outcome
15.
Psychopharmacol Bull ; 41(1): 85-98, 2008.
Article in English | MEDLINE | ID: mdl-18362873

ABSTRACT

BACKGROUND: Second-generation atypical antipsychotics improve the outcome of patients with schizophrenia, although studies of their cost efficacy in comparison to first-generation conventional antipsychotics have yielded mixed results. OBJECTIVES: This study examines the cost effectiveness outcome of olanzapine treatment in veterans with schizophrenia (n 5 22) or schizoaffective disorder (n 5 4). METHODS: Health-care utilization and costs associated with prospective olanzapine treatment were compared with those of retrospective first-generation neuroleptic treatment in a mirror-image design. RESULTS: The analysis of variance with repeated measures for the Positive and Negative Syndrome Scale (PANSS; n 5 22) showed a significant main effect of olanzapine treatment (p , .025), and the effect was of medium-to-large size (h2 5 .13). The PANSS-positive subscale (p , .005) and the PANSS general subscale (p , .005) significantly decreased, but the PANSS negative subscale did not change. The quality of life survey (n 5 21) significantly increased (p , .025), and the effect size was large (h2 5 .14). For VA outpatient and inpatient care, study patients incurred an average cost difference of 2$1,289 (NS) and 2$6,682 (NS), respectively. Combining inpatient and outpatient VA care, patients incurred an annual difference of 2$7,971 per patient (NS). These numerically lower costs were due, in part, to a slower growth rate in outpatient encounters (p 5 .013), lower overall cost per outpatient encounter (p 5 .008), and a lower overall inpatient encounter rate (p 5 .005). CONCLUSIONS: Olanzapine treatment resulted in improvements in positive and general psychiatric symptoms, as well as quality of life. Negative symptoms did not change significantly. Though not statistically significant, the postbaseline health-care costs and utilization declined.


Subject(s)
Antipsychotic Agents/therapeutic use , Benzodiazepines/therapeutic use , Economics, Pharmaceutical , Psychotic Disorders/drug therapy , Schizophrenia/drug therapy , Adult , Aged , Antipsychotic Agents/economics , Benzodiazepines/economics , Cost-Benefit Analysis , Female , Health Care Costs , Humans , Male , Middle Aged , Olanzapine , Quality of Life , Retrospective Studies , Veterans
16.
J Clin Psychopharmacol ; 28(1): 84-8, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18204347

ABSTRACT

OBJECTIVE: To evaluate the efficacy of divalproex for the treatment of posttraumatic stress disorder (PTSD) hyperarousal symptom cluster. METHOD: Under double-blind conditions, 85 US military veterans with PTSD were randomized to treatment with divalproex or placebo for 8 weeks. All patients who received at least 1 dose of medication and 1 postbaseline assessment (n = 82) were included in the efficacy population. The primary outcome measure was the hyperarousal subscale of the Clinician-Administered PTSD Scale. RESULT: There were no significant intergroup differences in primary or secondary end points. The final mean (SD) divalproex dose and serum valproic acid level were 2309 +/- 507 mg/d and 82 +/- 30 mg/L, respectively. CONCLUSIONS: Divalproex monotherapy was not effective in the treatment of chronic PTSD in predominantly older male combat veterans. Further study is needed to determine the efficacy of divalproex in the management of PTSD in women or civilians or in combination with antidepressants.


Subject(s)
Combat Disorders/drug therapy , GABA Agents/therapeutic use , Stress Disorders, Post-Traumatic/drug therapy , Valproic Acid/therapeutic use , Chronic Disease , Combat Disorders/psychology , Delayed-Action Preparations , Double-Blind Method , Female , GABA Agents/blood , Humans , Male , Middle Aged , Psychiatric Status Rating Scales , Stress Disorders, Post-Traumatic/psychology , Treatment Outcome , Valproic Acid/blood , Veterans
17.
J Pain ; 8(12): 938-49, 2007 Dec.
Article in English | MEDLINE | ID: mdl-17690017

ABSTRACT

UNLABELLED: This randomized clinical trial (RCT) examined the efficacy of a cognitive-behavioral treatment (CBT) specifically targeted toward reducing pain catastrophizing for persons with chronic headache. Immediate treatment groups were compared with wait-list control groups. Differential treatment gains based on the order of presentation of 2 components of CBT (cognitive restructuring and cognitive/behavioral coping) and the role of catastrophizing in treatment outcome were examined. Thirty-four participants enrolled in a 10-week group treatment and 11 completed a wait-list self-monitoring period. Participants reported significant reductions in catastrophizing and anxiety and increased self-efficacy compared with wait-list control subjects, and these were maintained at follow-up. Although we did not find overall differences in the reduction of headache frequency or intensity compared with wait-list control subjects, calculation of clinical significance on headache indicators suggest that approximately 50% of treated participants showed meaningful changes in headache indices as well. Order of treatment modules was not related to gains during treatment or at follow-up; however, almost all changes occurred during the second half of treatment, suggesting that duration of treatment participation is important. PERSPECTIVE: Cognitive-behavioral treatment targeting reduction of catastrophizing for chronic headache pain reduced negative cognitive and affective variables associated with recurrent headache, increased headache management self-efficacy, and in half of the participants, produced clinically meaningful reductions in headache indicators. Length of treatment is an important factor to consider when providing CBT for chronic pain.


Subject(s)
Cognitive Behavioral Therapy/methods , Headache Disorders/psychology , Headache Disorders/therapy , Adult , Double-Blind Method , Female , Humans , Male , Middle Aged , Pain Measurement , Treatment Outcome
18.
J Behav Med ; 29(6): 511-22, 2006 Dec.
Article in English | MEDLINE | ID: mdl-16960758

ABSTRACT

The primary objective of this study was to examine whether individuals with chronic pain ("participants") and their spouses agree on perceptions of solicitous, distracting, and punishing spouse responses to pain. The second aim was to examine the role of participant catastrophizing (a negative mental set about pain), participant and spouse marital satisfaction, and participant and spouse depression in participant perceptions of spouse responses, spouse perceptions of their responses, and agreement between participants and spouses. Individuals with chronic musculoskeletal pain and their spouses (N=108 couples) completed questionnaire packets. Examination of overall group averages (participants vs. spouses) indicated little or no differences between participant and spouse ratings. Examination of individual agreement in participant and spouse ratings indicated substantial disagreement. The proposed moderators predicted both participant and spouse perceptions and jointly made minor contributions to dyad agreement. Although neither participant nor spouse perceptions of spouse responses are necessarily a reflection of actual behavior, the lack of agreement in this study suggests it may not be valid to use only patient perceptions in research related to spouse responses.


Subject(s)
Depression/psychology , Pain/psychology , Personal Satisfaction , Social Behavior , Spouses/psychology , Chronic Disease , Female , Humans , Male , Michigan , Middle Aged , Multivariate Analysis , Regression Analysis , Social Perception
19.
Psychol Assess ; 18(1): 81-8, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16594815

ABSTRACT

Factor analyses of the Beck Depression Inventory--II (A. T. Beck, R. A. Steer, & G. K. Brown, 1996) have frequently produced 2 different 2-factor oblique structures. The author used confirmatory factor analyses to compare these structures with a general-factor model with 2 orthogonal group factors. The general-factor model fit as well as or better than the 2-factor models when applied to item data from previous studies (3 clinical and 2 college samples). Communalities associated with the General Depression factor ranged from 71% to 82%. Cognitive and Somatic group factors were indicative of intropunitiveness and fatigue. It was concluded that the general-factor model gives an acceptable empirical explanation of item covariance structure and offers a conceptual interpretation that is well suited to clinical practice and research.


Subject(s)
Depressive Disorder, Major/diagnosis , Surveys and Questionnaires , Adult , Factor Analysis, Statistical , Female , Humans , Male , Severity of Illness Index
20.
J Pers Assess ; 86(2): 206-16, 2006 Apr.
Article in English | MEDLINE | ID: mdl-16599795

ABSTRACT

Factor analytic studies of the 24-item Personal Attributes Questionnaire (Spence & Helmreich, 1978) have reported inconsistent results, and a previous confirmatory factor analysis (CFA) indicated inadequate fit for factors corresponding to Masculinity, Femininity, and Masculinity-Femininity scales. In this research, we used CFA in a college sample (N = 382) to evaluate the 3-factor model, and we revised scales by eliminating 6 misspecified items. The revised model fit well in another college sample (N = 230). We renamed the revised scales Agency, Communion, and Emotional Vulnerability. In relation to Five-factor theory, Emotional Vulnerability and Communion correlated well with Neuroticism and Agreeableness, respectively, and Agency had moderate correlations with Neuroticism, Extraversion, and Conscientiousness. Psychometric results in the context of current theory suggest that Agency (Masculinity) may not be a fully adequate measure of the agency construct.


Subject(s)
Emotions , Surveys and Questionnaires , Adolescent , Adult , Extraversion, Psychological , Female , Humans , Interpersonal Relations , Male , Neurotic Disorders , Psychometrics , Sex Factors , Social Identification
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