Quality Review of Prone Patient Transport Protocol.

OBJECTIVE: This is a retrospective quality review of LifeFlight Nova Scotia's prone patient transport protocol. METHODS: Electronic patient care records were queried for acute respiratory distress syndrome, prone position, proning, supine to prone, and prone to prone between February 2017 and June 2022. Eligible electronic patient care records were reviewed for demographics (sex, age, and weight); method of transports (ambulance, rotor wing, or fixed wing); duration of transports; mechanical ventilation parameters; medication infusions; arterial blood gases; occurrences of mild hypoxemia (any oxygen saturation [SpO2] < 88% or decrease in SpO2 > 5%); hypotension (any episode of MAP < 65 mm Hg); severe hypoxemia (any SpO2 < 80% or decrease in SpO2 > 10%); refractory hypotension (mean arterial pressure < 65 mm Hg not responsive to vasopressor/inotropes); cardiac arrests; and displacement of central lines, arterial lines, and endotracheal tubes. RESULTS: Seventeen prone patients were transported by ambulance, rotor wing, and fixed wing with 4 occurrences of mild hypotension, 4 occurrences of mild hypoxemia, and 1 occurrence of refractory hypotension. CONCLUSION: Interfacility transfer of prone patients by a dedicated critical care team is feasible with minimal adverse occurrences while ensuring patients have access to the specialized lifesaving care they require.

Lung Mechanics Tracking with Forced Oscillation Technique (FOT) Based on CMOS Synchronous Demodulation Principle.

In this paper, an area-efficient CMOS integrated solution for lung impedance extraction is presented. The lock-in principle is leveraged for its high effective bandpass selectivity, to acquire information about the airways, through stimulation by FOT (Forced Oscillation Technique). The modulated pressure and flow signals are down-converted by a quadrature voltage commutating passive mixer-first receiver. In addition to its linearity, and unlike the Gilbert cell, it can be biased at zero dc current to alleviate flicker noise contributions. The proposed solution is designed and fabricated in 0.18µm TSMC technology. The chip occupies an active silicon area of 4.7 mm2 (including buffers and pads) and dissipates 429.63 µW. The proposed approach offers real time tracking of respiratory mechanics and is expected to be a promising solution for portable health monitoring and cost-effective biomedical devices.

Understanding burnout and moral distress to build resilience: a qualitative study of an interprofessional intensive care unit team.

OBJECTIVE: The purpose of this study was to explore personal and organizational factors that contribute to burnout and moral distress in a Canadian academic intensive care unit (ICU) healthcare team. Both of these issues have a significant impact on healthcare providers, their families, and the quality of patient care. These themes will be used to design interventions to build team resilience. METHODS: This is a qualitative study using focus groups to elicit a better understanding of stakeholder perspectives on burnout and moral distress in the ICU team environment. Thematic analysis of transcripts from focus groups with registered intensive care nurses (RNs), respiratory therapists (RTs), and physicians (MDs) considered causes of burnout and moral distress, its impact, coping strategies, as well as suggestions to build resilience. RESULTS: Six focus groups, each with four to eight participants, were conducted. A total of 35 participants (six MDs, 21 RNs, and eight RTs) represented 43% of the MDs, 18.8% of the RNs, and 20.0% of the RTs. Themes were concordant between the professions and included: 1) organizational issues, 2) exposure to high-intensity situations, and 3) poor team experiences. Participants reported negative impacts on emotional and physical well-being, family dynamics, and patient care. Suggestions to build resilience were categorized into the three main themes: organizational issues, exposure to high intensity situations, and poor team experiences. CONCLUSIONS: Intensive care unit team members described their experiences with moral distress and burnout, and suggested ways to build resilience in the workplace. Experiences and suggestions were similar between the interdisciplinary teams.

RéSUMé: OBJECTIF: L'objectif de cette étude était d'explorer les facteurs personnels et organisationnels contribuant à l'épuisement professionnel et à la détresse morale dans une équipe de soins de santé d'une unité de soins intensifs (USI) universitaire canadienne. Ces deux problèmes ont un impact significatif sur les fournisseurs de soins de santé, sur leurs familles, et sur la qualité des soins aux patients. Ces thèmes seront utilisés pour concevoir des interventions afin de développer la résilience d'équipe. MéTHODE: Nous avons réalisé une étude qualitative utilisant des groupes de réflexion afin de mieux comprendre les perspectives des personnes concernées par l'épuisement professionnel et la détresse morale dans l'environnement des équipes d'USI. L'analyse thématique des transcriptions des groupes de réflexion, composés d'infirmières et infirmiers, d'inhalothérapeutes et de médecins intensivistes, prenait en considération les causes d'épuisement professionnel et de détresse morale, leur impact, les stratégies d'adaptation, ainsi que les suggestions pour développer la résilience. RéSULTATS: Six groupes de réflexion, chacun comptant quatre à huit participants, ont été créés. Au total, 35 participants (six médecins, 21 infirmières et infirmiers, et huit inhalothérapeutes), représentant 43 % des médecins, 18,8 % des infirmières et infirmiers, et 20,0 % des inhalothérapeutes, ont pris part à nos groupes de réflexion. Les thèmes concordaient entre les professions et comprenaient : 1) les problèmes organisationnels, 2) l'exposition à des situations de stress élevé, et 3) les mauvaises expériences d'équipe. Les participants ont rapporté des impacts négatifs sur leur bien-être émotionnel et physique, les dynamiques familiales, et les soins aux patients. Les suggestions pour développer la résilience étaient catégorisées en trois thèmes principaux : problèmes organisationnels, exposition à des situations de stress élevé, et mauvaises expériences d'équipe. CONCLUSION: Les membres des équipes de l'unité de soins intensifs ont décrit leurs expériences en ce qui a trait à la détresse morale et à l'épuisement professionnel, et suggéré des façons de développer la résilience sur le lieu de travail. Les expériences et suggestions étaient similaires dans les différentes équipes interdisciplinaires.

Mapping the Expert Mind: Integration Method for Revising the ACES Medical Simulation Curriculum.

PURPOSE: This article shares our experience developing an integrated curriculum for the ACES (Acute Critical Event Simulation) program. The purpose of the ACES program is to ensure that health care providers develop proficiency in the early management of critically ill patients. The program includes multiple different types of educational interventions (mostly simulation-based) and targets both specialty and family physicians practicing in tertiary and community hospitals. METHODS: To facilitate integration between different educational interventions, we developed a knowledge repository consisting of cognitive sequence maps that make explicit the flow of cognitive activities carried out by experts facing different situations - the sequence maps then serving as the foundation upon which multimodal simulation scenarios would be built. To encourage participation of experts, we produced this repository as a peer-reviewed ebook. Five national organizations collaborated with the Royal College of Physicians and Surgeons of Canada to identify and recruit expert authors and reviewers. Foundational chapters, centered on goals/interventions, were first developed to comprehensively address most tasks conducted in the early management of a critically ill patient. Tasks from the foundational chapters were then used to complete the curriculum with situations. The curriculum development consisted of two-phases each followed by a peer-review process. In the first phase, focus groups using web-conferencing were conducted to map clinical practice approaches and in the second, authors completed the body of the chapter (e.g., introduction, definition, concepts, etc.) then provided a more detailed description of each task linked to supporting evidence. RESULTS: Sixty-seven authors and thirty-five peer reviewers from various backgrounds (physicians, pharmacists, nurses, respiratory therapists) were recruited. On average, there were 32 tasks and 15 situations per chapter. The average number of focus group meetings needed to develop a map (one map per chapter) was 6.7 (SD ± 3.6). We found that the method greatly facilitated integration between different chapters especially for situations which are not limited to a single goal or intervention. For example, almost half of the tasks of the Hypercapnic Ventilatory Failure chapter map were borrowed from other maps with some modifications, which significantly reduced the authors' workload and enhanced content integration. This chapter was also linked to 6 other chapters. CONCLUSIONS: To facilitate curriculum integration, we have developed a knowledge repository consisting of cognitive maps which organize time-sensitive tasks in the proper sequence; the repository serving as the foundation upon which other educational interventions are then built. While this methodology is demanding, authors welcomed the challenge given the scholarly value of their work, thus creating an interprofessional network of educators across Canada.

Transport of a Prone Position Acute Respiratory Distress Syndrome Patient.

We report the case of a non-physician based critical care transport team (registered nurse and paramedic) that successfully initiated prone positioning of a severe acute respiratory distress patient prior to transport to an extracorporeal membrane oxygenation capable teaching hospital. With the increasing use of advanced treatments such as extracorporeal membrane oxygenation, prone positioning, and continuous renal replacement therapy for severe acute respiratory distress syndrome (ARDS), the necessity to transport these patients to specialized hospitals will correspondingly increase. Emergency Health Services Life Flight, the primary critical care transport program in Eastern Canada, developed a prone position protocol to meet this clinical need. Since the implementation of the protocol, we have successfully initiated prone positioning of 2 patients with ARDS before transport to an extracorporeal membrane oxygenation- and continuous renal replacement therapy-capable teaching hospital. This represents the first report of a nonphysician (registered nurse and paramedic) critical care team initiating prone positioning before transport. Consent for publication was only obtained in the second case, which we present here.

The effect of simulator fidelity on acquiring non-technical skills: a randomized non-inferiority trial.

INTRODUCTION: As simulator fidelity (i.e., realism) increases from low to high, the simulator more closely resembles the real environment, but it also becomes more expensive. It is generally assumed that the use of high-fidelity simulators results in better learning; however, the effect of fidelity on learning non-technical skills (NTS) is unknown. This was a non-inferiority trial comparing the efficacy of high- vs low-fidelity simulators on learning NTS. METHODS: Thirty-six postgraduate medical trainees were recruited for the trial. During the pre-test phase, the trainees were randomly assigned to manage a scenario using either a high-fidelity simulator (HFS) or a low-fidelity simulator (LFS), followed by expert debriefing. All trainees then underwent a video recorded post-test scenario on a HFS, and the NTS were assessed between the two groups. The primary outcome was the overall post-test Ottawa Global Rating Scale (OGRS), while controlling for overall pre-test OGRS scores. Non-inferiority between the LFS and HFS was based on a non-inferiority margin of greater than 1. RESULTS: For our primary outcome, the mean (SD) post-test overall OGRS score was not significantly different between the HFS and LFS groups after controlling for pre-test overall OGRS scores [3.8 (0.9) vs 4.0 (0.9), respectively; mean difference, 0.2; 95% confidence interval, -0.4 to 0.8; P = 0.48]. For our secondary outcomes, the post-test total OGRS score was not significantly different between the HFS and LFS groups after controlling for pre-test total OGRS scores (P = 0.33). There were significant improvements in mean overall (P = 0.01) and total (P = 0.003) OGRS scores from pre-test to post-test. There were no significant associations between postgraduate year (P = 0.82) and specialty (P = 0.67) on overall OGRS performance. CONCLUSION: This study suggests that low-fidelity simulators are non-inferior to the more costly high-fidelity simulators for teaching NTS to postgraduate medical trainees.

Is Admission to the Intensive Care Unit Associated With Chronic Opioid Use? A 4-Year Follow-Up of Intensive Care Unit Survivors.

PURPOSE: To describe opioid use before and after intensive care unit (ICU) admission and to identify factors associated with chronic opioid use upto 4 years after ICU discharge. METHODS: Retrospective review of adult patients admitted to the ICU at a tertiary care center between January 1, 2005, to December 31, 2008. We defined "nonuser," "intermittent," and "chronic" opioid status by abstinence, use in <70%, and >70% of days for a given time period, respectively. We assessed opioid use at 3 months prior to ICU admission, at discharge, and annually for upto 4 years following ICU discharge. RESULTS: A total of 2595 ICU patients were included for surgical (48.6%), medical (38.4%), and undetermined (13%) indications. The study population included both elective (26.9%) and emergent (73.1%) admissions. Three months prior to ICU admission, 76.9% were nonusers, 16.9% used opioids intermittently, and 6.2% used opioids chronically. We found an increase in nonuser patients from 87.8% in the early post-ICU period to 95.6% at 48-month follow-up. Consequently, intermittent and chronic opioid use dropped to 8.6% and 3.6% at discharge and 2.6% and 1.8% at 48-month follow-up, respectively. Prolonged hospital length of stay was associated with chronic opioid use. CONCLUSION: Admission to ICU and duration of ICU stay were not associated with chronic opioid use.

Intravenous free and dipeptide-bound glutamine maintains intestinal microcirculation in experimental endotoxemia.

OBJECTIVE: The administration of glutamine (Gln), which is depleted in critical illness, is associated with an improvement of gut metabolism, structure, and function. The aim of the present study was to evaluate the effects of intravenous Gln and its galenic formulation, l-alanyl-l-glutamine dipeptide (AlaGln), on the intestinal microcirculation during experimental endotoxemia using intravital fluorescence microscopy. Gln or AlaGln administration was performed as pretreatment or post-treatment, respectively. To identify further the underlying mechanisms, amino acid levels were studied. METHODS: Sixty male Lewis rats were randomly divided into six groups (n = 10/group): control, LPS (lipopolysaccharide 5 mg/kg intravenously), Gln/LPS (LPS animals pretreated with Gln 0.75 g/kg Gln intravenously), AlaGln/LPS (LPS animals pretreated with AlaGln intravenously, 0.75 g/kg Gln content), LPS/Gln (LPS animals post-treated with Gln 0.75 g/kg intravenously), and LPS/AlaGln (LPS animals post-treated with AlaGln intravenously, 0.75 g/kg Gln content). Two hours after the endotoxin challenge, the microcirculation of the terminal ileum was studied using intravital fluorescence microscopy. Blood samples were drawn at the beginning, during, and the end of the experiment to determine the amino acid levels. RESULTS: The Gln and AlaGln pre- and post-treatment, respectively, prevented the LPS-induced decrease in the functional capillary density of the intestinal muscular and mucosal layers (P < 0.05). The number of adherent leukocytes in the submucosal venules was significantly attenuated after the Gln and AlaGln pre- and post-treatment (P < 0.05). CONCLUSION: The Gln and AlaGln administrations improved the intestinal microcirculation by increasing the functional capillary density of the intestinal wall and decreasing the submucosal leukocyte activation.