Progressive angiomatosis, resembling human skeletal-extraskeletal angiomatosis, arising in multiple digits in two dogs.

Two dogs presented with progressive, expansile and invasive lesions on a hind paw. Case 1, a 10-year-old female Shetland sheepdog had diffusive and aggressive-looking lesions on the middle digits of the left hind paw. Radiographic examination showed invasion into and destruction of the underlying bone. A malignant tumour was suspected initially; however, histological features of atypical vascular proliferations without mitotic activity were consistent with progressive angiomatosis. Case 2, an 11-year-old female English springer spaniel presented with similar lesions in the same toes, also involving bone. Progressive angiomatosis was suspected clinically, as tumour cells were not detected by cytology and screening did not detect metastatic disease. Histopathology confirmed the diagnosis. Progressive angiomatosis is an uncommon non-malignant condition which should be considered as a differential diagnosis for radiographically lytic digital lesions.

Atypical interstitial pneumonia in grazing adult red deer (Cervus elaphus).

A herd of red deer experienced a small outbreak of atypical interstitial pneumonia on two occasions 3 years apart. The first occasion involved the death of two of a group of 70 hinds and the second outbreak involved a single death in a similar sized group. On both occasions a number of the adults exhibited increased respiratory effort, particularly on exercise. Both outbreaks occurred in July, a few days after moving the herd from a close grazed grass paddock to an aftermath paddock, which had regrown to a good sward. The history and pathology is reminiscent of 3-methyl indole toxicity in cattle.

Sarcina-like bacteria associated with bloat in young lambs and calves.

Sarcina species are fastidious Gram-positive anaerobic bacteria that occur in cubical packets of eight or more cells. In 2006 to 2007, they were associated with cases of acute abomasal bloat in young lambs and calves. Two incidents were in lambs aged three to six weeks that were found dead, with one or two cases in each of a group of 15 and 100 lambs. Three incidents were recorded in small groups of calves up to 10 days of age, two cases in each incident, with the calves found dead or dying after a short illness characterised by bloat. Their gross lesions included emphysema and oedema of the abomasal wall, mucosal hyperaemia and haemorrhage, and rupture of the abomasum. Histological lesions included abomasitis with congestion, haemorrhage, emphysema and oedema. Bacteria characteristic of Sarcina species were observed in sections associated with the superficial mucosa of these cases, but the bacteria were not detected in cultures.

Panniculitis, polyarthritis and osteomyelitis associated with pancreatic neoplasia in two dogs.

A 12-year-old crossbred dog (case 1) and a 12-year-old Shetland sheepdog (case 2) were presented with a history of lameness and distal limb swelling. Physical examination revealed joint effusions and asymmetrical swellings of the extremities. In case 1, a diagnosis of arthritis and cellulitis was made on fine-needle aspiration biopsy of the synovium and subcutis. In case 2, bone biopsies and synovial aspirates diagnosed osteomyelitis and arthritis. A diagnosis of pancreatic disease was made on the findings of marked elevations of serum lipase concentrations and ultrasonographic identification of pancreatic masses in both cases. Both the cases were non-responsive to symptomatic management and were subsequently euthanased. Postmortem examination confirmed the diagnosis of panniculitis, arthritis and osteomyelitis in both cases. A pancreatic exocrine adenoma was identified in case 1 and a pancreatic adenocarcinoma with widespread metastases in case 2. To the authors' knowledge the association of panniculitis, polyarthritis and osteomyelitis with pancreatic disorders has not been reported previously in canine clinical cases.

Acute B cell lymphoblastic leukaemia in a 12-week-old greyhound.

A 12-week-old greyhound had a two-day history of lethargy, inappetence and shifting lameness. Clinical examination revealed pyrexia and hepatosplenomegaly. Haematological examination showed anaemia, thrombocytopenla, neutropenla and large numbers of atypical mononuclear leucocytes. A diagnosis of acute B cell lymphoblastic leukaemia was made following flow cytometric immunophenotyping of the leucocytes. The owner declined further evaluation and the dog was treated symptomatically with antibiotics. After a brief improvement, the dog's condition deteriorated and it was euthanased four days after initial presentation. The case was unusual because acute lymphoid leukaemia in the dog is most frequently reported in mature animals. This is in contrast to humans, where acute leukaemia is one of the most common childhood cancers.

Magnetic resonance imaging and neuropathology findings in the goat nervous system following hyperbaric exposures.

Divers may be at risk of long-term CNS damage from non-symptomatic hyperbaric exposure. We investigated the effect of severe, controlled hyperbaric exposure on a group of healthy goats with similar histories. Thirty goats were exposed to various dive profiles over a period of 5 years, with 17 experiencing decompression sickness (DCS). Brains were scanned using magnetic resonance (MR) imaging techniques. The animals were then culled and grossly examined, with the brain and spinal cord sent for neuropathological examination. No significant correlation was found between age, years diving, DCS or exposure to pressure with MR-detectable lesions in the brain, or with neuropathological lesions in the brain or spinal cord. However, spinal scarring was noted in 3 animals that had suffered from spinal DCS.

Magnetic resonance imaging in the diagnosis of lymphoma involving the brachial plexus in a cat.

An 11-year-old, neutered, female Domestic Long Hair cat had a 3-week history of left forelimb lameness. Conscious proprioception and postural reflexes were absent on the left thoracic limb. The cat had slightly reduced placing and hopping responses on the left pelvic limb, absent cutaneous trunci muscle reflex on the left side, and left triceps muscle atrophy. Magnetic resonance imaging revealed a 2 x 2 x 2 cm mass in the region of the left brachial plexus. The cat was treated by left forelimb amputation and hemilaminectomy. Histopathology of the brachial plexus revealed lymphoma.

Primary chondrosarcoma in the pulmonary artery of a dog.

A 5-year-old cross-bred dog was examined with an 8-week history of coughing and a 3-week history of collapsing during exercise. Thoracic radiography revealed moderate right-sided cardiomegaly and a partially mineralized area over the dorsocranial heart base. Echocardiography demonstrated moderate eccentric and concentric right ventricular hypertrophy and a hypoechoic mass in the main pulmonary artery. The owners declined further investigations and the dog died at home 4 days later. Postmortem revealed a primary pulmonary artery chondrosarcoma. This is the first case report of a pulmonary artery chondrosarcoma in a dog and presents another differential diagnosis of syncope in the dog.

Anal sac adenocarcinoma in a Siamese cat.

A 12-year-old male neutered Siamese cat presented with a history of inappetance and lethargy and an enlarged left anal sac. The anal sac was surgically excised and histopathology confirmed the diagnosis of anal sac adenocarcinoma. Perianal tumours are rare in the cat and anal sac adenocarcinoma has not been previously reported. This is in contrast to the dog where anal sac adenocarcinoma is a well recognised albeit uncommon tumour.