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1.
Dis Colon Rectum ; 42(11): 1438-48, 1999 Nov.
Article in English | MEDLINE | ID: mdl-10566532

ABSTRACT

PURPOSE: Pelvic recurrence of rectal cancer is an ominous event for the patient and a formidable challenge to the managing surgeon. We reviewed the results of abdominosacral resection to manage these patients and correlated outcome (survival and recurrence) with known prognostic factors. METHODS: An abdominosacral resection was performed on 61 patients with pelvic recurrence (53 with curative intent and 6 for palliation; 2 had extended pelvic resection). Of the 53 patients (32 males; average age, 59 years) previous resection included abdominoperineal resection in 27 patients, abdominoperineal resection plus hepatic lobectomy in 2 patients, low anterior resection in 19 patients, plus trisegmentectomy in 1 patient, and advanced primary cancers in 4 patients. Initial primary stage was Dukes B (64 percent) and Dukes C (36 percent). All had been irradiated (3,000-6,500 in 50 patients, 8,300 and 11,000 in 2 patients, and unknown dose in 3 patients). Preoperative carcinoembryonic antigen was elevated (>5 ng/ml) in 54 percent. Extent of resection: high sacral resection S-1-S2 was done in 32 patients, midsacrum in 14 patients, and low S-4-S-5 in 6 patients. Twenty-eight patients (60 percent) required partial or complete bladder resection with or without adjacent viscera, and all had internal iliac and obturator node dissection. RESULTS: There were four postoperative (within 60 days) deaths, 8 percent in curative groups (5.4 percent overall). Major complications included prolonged intubation (20 percent), sepsis (34 percent), posterior wound infection or flap separation (38 percent). The survival rate in the curative group (49 postoperative survivors) was 31 percent at five years, with 13 patients surviving beyond five years. Seven of these patients survived from 5 to 21 years, whereas six patients recurred again and died within 5.5 to 7.5 years after abdominosacral resection. Disease-free survival rate at five years was 23 percent. Recent reconstruction with large composite myocutaneous gluteal flaps in 5 patients permitted complete sacral wound coverage, resulting in earlier ambulation and reduced hospital stay. CONCLUSIONS: Abdominosacral resection permits removal of pelvic recurrence of rectal cancer that is fixed to the sacrum and is associated with long-term survival in 31 percent of patients. Recent technical advances have improved the short-term outcome and have made the procedure more feasible for surgical teams familiar with these techniques.


Subject(s)
Digestive System Surgical Procedures/methods , Neoplasm Recurrence, Local/surgery , Pelvis/surgery , Rectal Neoplasms/surgery , Sacrum/surgery , Abdomen/surgery , Adult , Aged , Angiography , Biopsy, Needle , Disease-Free Survival , Female , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/mortality , Postoperative Complications , Rectal Neoplasms/diagnosis , Rectal Neoplasms/mortality , Retrospective Studies , Survival Rate , Tomography, X-Ray Computed , Treatment Outcome
2.
R I Med ; 78(6): 172-3, 1995 Jun.
Article in English | MEDLINE | ID: mdl-7626817

ABSTRACT

A retrospective review of 384 patients who had undergone rubber band ligation for hemorrhoidal disease by one surgeon from 1988 to 1993 is presented. The primary indications for treatment were rectal bleeding and prolapse. Eighty-nine percent of the patients were improved following treatment. In selected patients, rubber band ligation is an acceptable alternative to surgical hemorrhoidectomy.


Subject(s)
Hemorrhoids/therapy , Humans , Ligation/instrumentation , Ligation/methods , Retrospective Studies , Treatment Outcome
3.
Ann Surg ; 220(4): 586-95; discussion 595-7, 1994 Oct.
Article in English | MEDLINE | ID: mdl-7524455

ABSTRACT

OBJECTIVE: The authors describe their experience with pelvic resection of recurrent rectal cancer with emphasis on patient selection for curative intent based on known tumor risk factors. SUMMARY BACKGROUND DATA: Pelvic recurrence is a formidable problem in 30% of patients who have undergone a curative resection of primary rectal cancer. Although radiation can reduce the development of local recurrence and can provide palliation to many patients with localized disease, it is not curative. The authors and others have used the technique of abdominal sacral resection (ABSR) with or without pelvic exenteration to resect pelvic recurrence and its musculoskeletal extensions in selected patients with satisfactory long-term survival. METHODS: The technique of ABSR with or without pelvic exenteration or resection of pelvic viscera, which the authors have described previously, was used in 53 patients with recurrent rectal cancer--47 patients for curative intent and 6 for palliation. Previous surgeries were abdominal perineal resections (APRs) in 26 patients, anterior resections in 19 patients, and other procedures in 2 patients; original primary Dukes' stage was B in 52% and C in 48%. Almost all patients had been irradiated previously, generally in the 4000 to 5900 cGy range. Preoperative carcinoembryonic antigen (CEA) levels (before ABSR) were elevated (> 5 ng/mL) in 54%. RESULTS: Postoperative morbidity was encountered in most patients. Mortality was 8.5% in the curative group. Long-term survival for 4 years was achieved in 14 of 43 patients (33%), and 10 patients were alive with an acceptable quality of life after 5 years. Patients who had previous anterior resections or whose preoperative CEA levels were less than 10 ng/mL had a survival rate of approximately 45%, whereas patients with previous APRs and preoperative CEA levels greater than 10 ng/mL had a survival rate of only 15% to 18%. Patients with bone marrow invasion, positive margins, or pelvic node metastases had a median survival of only 10 months. CONCLUSIONS: Pelvic recurrence of rectal cancer can be resected safely with expectation of long-term survival of 33%. Patient selection based on known risk factors can identify patients most likely to benefit from resection and eliminate those who should be treated for palliation only.


Subject(s)
Neoplasm Recurrence, Local/surgery , Palliative Care/methods , Pelvic Exenteration , Rectal Neoplasms/surgery , Rectum/surgery , Carcinoembryonic Antigen/blood , Disease-Free Survival , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/mortality , Postoperative Complications/epidemiology , Radiotherapy, Adjuvant , Rectal Neoplasms/mortality , Rectal Neoplasms/radiotherapy , Reoperation , Survival Analysis
4.
Dis Colon Rectum ; 23(7): 478-82, 1980 Oct.
Article in English | MEDLINE | ID: mdl-7438950

ABSTRACT

Records of 266 patients who had undergone rubber ring ligation for hemorrhoidal complaints from 1969 through 1976 were reviewed to evaluate the long-term results. The minimum follow-up period was 36 months, with a mean of 60 months. Of the patients, 80 per cent were improved, with 69 per cent totally free of all symptoms. A subsequent hemorrhoidectomy was required in 7.5 per cent. Results were similar when either bleeding or prolapse was the primary indication for treatment. Patients who had a single band applied fared as well as those with two or more ligations.


Subject(s)
Hemorrhoids/surgery , Adult , Aged , Evaluation Studies as Topic , Female , Follow-Up Studies , Humans , Ligation/instrumentation , Male , Middle Aged , Postoperative Complications , Rubber
5.
Dis Colon Rectum ; 22(8): 569-72, 1979.
Article in English | MEDLINE | ID: mdl-527453

ABSTRACT

Two cases of evisceration of the small intestine through a spontaneous perforation of the distal large bowel are presented, and the literature is reviewed. The condition is associated with a sudden increase in intra-abdominal pressure and a past history of rectal prolapse. The etiology and management of this problem are discussed.


Subject(s)
Anal Canal , Colonic Diseases/complications , Intestine, Small , Aged , Female , Hernia , Humans , Intestinal Diseases/etiology , Intestinal Diseases/surgery , Intestine, Small/surgery , Male , Middle Aged , Prolapse , Rectal Prolapse/etiology , Rupture, Spontaneous
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