Subject(s)
Bone Marrow , Fluorodeoxyglucose F18 , Liver , Positron Emission Tomography Computed Tomography , Spleen , HumansABSTRACT
An extragastrointestinal stromal tumor (EGIST) refers to the gastrointestinal stromal tumor in any location outside the gastrointestinal tract originates from mesenchymal tumors. The majority of the EGIST appeared as isolated mass, and multiple primary EGIST is quite rare. Here, we report a 36-year-old man of multiple EGIST in the abdominopelvic cavity, which was misdiagnosed as lymphoma on fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging. The patient received adjuvant drug treatment (imatinib, 400mg/day) for three months, and then further resection of all lesions was performed. No recurrence was found in CT follow-up one year after the operation.
Subject(s)
Fluorodeoxyglucose F18 , Gastrointestinal Stromal Tumors/drug therapy , Neoplasms, Multiple Primary/diagnostic imaging , Positron Emission Tomography Computed Tomography , Adult , Gastrointestinal Stromal Tumors/pathology , Humans , Imatinib Mesylate/therapeutic use , Male , Neoplasms, Multiple Primary/drug therapy , Neoplasms, Multiple Primary/pathologyABSTRACT
OBJECTIVE: To predict the early identification of recurrence based on magnetic resonance imaging (MRI) in nasopharyngeal cancer (NPC) patients. METHODS: The clinical and MRI data of 215 patients with local recurrent NPC were retrospectively reviewed. Logistic regression analysis was performed to distinguish the independent risk factors for the short-term (less than 24 months) local recurrence of NPC. The predictive score model was based on the regression coefficients of significant independent variables. RESULTS: Residual disease in the nasopharyngeal cavity (NC), masticator space invasion (MSI), skull base bone erosion (SBBE), and MRI-detected cranial nerve invasion (MDCNI) were all significant independent risk factors for the short-term recurrence of NPC (p < 0.05). The receiver operating characteristic curve showed that the total score had a maximal AUC (area under the curve) value of 0.897, with a cutoff point of 10.50. The sensitivity and specificity were 79.4% and 80.5%, respectively. CONCLUSION: Residual lesions in NC, MSI, SBBE, and MDCNI are independent risk factors in predicting the short-term recurrence of NPC. The authors' findings suggest that patients with a score of more than 10.50 points should be hypervigilant regarding the possibility of short-term recurrence.
