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Knockout of the NONO Gene Inhibits Neointima Formation in a Mouse Model of Vascular Injury.

Xu (å¾å´ä¸½), Xingli; Xu (å¾å´å), Xinghua; Mao (æ¯æ´), Yang; Lu (å¢ç³), Lin; Ma (é©¬é), Jing; Zheng (éè¾é£), Tengfei; Zhang (å¼ æ°), Jie; Zhang (ç« è), Meng; Meng (åéé), Linlin; Ma (é©¬è¿è¶), Lianyue; Cheng (ç¨æ¶), Jing; Chen (éæå¼º), Wenqiang; Jiang (å§è¹), Hong; Zhang (å¼ è¿), Yun; Zhang (å¼ æ¾), Cheng.

Arterioscler Thromb Vasc Biol ; 41(4): 1428-1445, 2021 04.

Article in English | MEDLINE | ID: mdl-33626912

ABSTRACT

[Figure: see text].

Subject(s)

Carotid Artery Injuries/metabolism , DNA-Binding Proteins/deficiency , Muscle, Smooth, Vascular/metabolism , Myocytes, Smooth Muscle/metabolism , Neointima , Animals , Carotid Artery Injuries/genetics , Carotid Artery Injuries/pathology , Carotid Artery, Common/metabolism , Carotid Artery, Common/pathology , Case-Control Studies , Cell Movement , Cell Proliferation , Coronary Artery Disease/genetics , Coronary Artery Disease/metabolism , Coronary Stenosis/genetics , Coronary Stenosis/metabolism , DNA-Binding Proteins/genetics , DNA-Binding Proteins/metabolism , Disease Models, Animal , Extracellular Signal-Regulated MAP Kinases/metabolism , Gene Knockout Techniques , Humans , Male , Mice , Mice, Inbred C57BL , Mice, Knockout , Muscle, Smooth, Vascular/pathology , Myocytes, Smooth Muscle/pathology , Phenotype , RAW 264.7 Cells , RNA-Binding Proteins/genetics , RNA-Binding Proteins/metabolism , Signal Transduction

ABSTRACT

Subject(s)

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